Gallamine triethiodide

Chemical Name 2,2 ,2 -[1,2,3-benzenetriyltris(oxv)]tris[N,N,N-triethylethanaminium] triiodide 

Common Name Benzcurine iodide Structural Formula  

The mixture is then heated for 1 hour, the toluene being refluxed, whereafter it is left to cool, 50 cc of water are added and, after decanting, the solution Is again washed with two quantities of 50 cc of water. The toluene solution is dried over potassium carbonate and distilled in vacuo. There is thus obtained 28 grams of 1.2.3-tri-(P-diethylaminoethoxy)-benzene, boiling at 206°C under 1 mm pressure. 

20 grams of 1.2.3-tri-(0-diethylaminoethoxy)-benzene is heated for 5 hours under reflux on the water bath with 30 grams of ethyl iodide. The hot mixture is dissolved in 50 cc of 

The triethiodide of 1.2.3-tri-((3-diethylaminoethoxy)-benzene is thus obtained as white crystals which, after drying, have a rather indefinite melting point at about 152° to 153°C, (Maquenne block). 

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Gallamine triethiodide Ibuprofen Nalidixic acid Oxetorone fumarate Oxolinic acid Piroheptine Rosoxacin Tridihexethyl iodide Ethyl 4-iodobutyrate Meptazinol... 

C2H5I 75-03-6) see Butibufen Cinoxacin Diethylstilbestrol Enoxacin Ethotoin Gallamine triethiodide Imiquimod Lomefloxacin Mosapride citrate Nalidixic acid Oxolinic acid Pefloxacin Pipemidic acid Tridihexethyl chloride Zaleplon... 

Many patents have been issued on the use of pyrogallol derivatives as pharmaceuticals. Pyrogallol has been used externally in the form of an ointment or a solution in the treatment of skin diseases, eg, psoriasis, ringworm, and lupus erythematosus. Gallamine triethiodide (16) is an important muscle relaxant in surgery it also is used in convulsive-shock therapy. Trimethoprim (2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine) is an antimicrobial and is a component of Bactrin and Septra. Trimetazidine (l(2,3,4-trimethoxybenzyl)piperazine (Vastarel, Yosimilon) is used as a coronary vasodilator. l,2,3,4-Tetrahydro-6-methoxy-l-(3,4,5-trimethoxyphenyl)-9.H-pyrido[3,4- ]indole hydrochloride is useful as a tranquilizer (52) (see HYPNOTICS, SEDATIVES, anticonvulsants, and anxiolytics). Substituted indanones made from pyrogallol trimethyl ether depress the central nervous system (CNS) (53). Tyrosine-and glycine(2,3,4-trihydroxybenzyl)hydrazides are characterized by antidepressant and anti-Parkinson activity (54). 

Trimetaphan camsylate is incompatible with alkaline preparations, bromides, iodides, gallamine triethiodide, and thiopentone sodium. Loss of urokinase is reported when diluted with glucose solutions in PVC intravenous infusion sets.127... 

Diquat Dibromide Distigmine Bromide Ethyl Nicotinate Gallamine Triethiodide Hexamethonium Bromide Hydrastinine Mebezonium Iodide Neomycin Noradrenaline Paraquat Dichloride Pentolinium Tartrate Quinuronium Sulphate Streptomycin Tubocurarine Chloride... 

Harrison JF, Bird AG. Anaphylaxis to precurarising doses of gallamine triethiodide. Anaesthesia 1986 41(6) 600. ... 

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