Neuropsychiatrically disordered

Neurological symptoms result from demyelination of the spinal cord and are potentially irreversible. The symptoms and signs characteristic of a vitamin B 2 deficiency include paresthesis of the hands and feet, decreased deep-tendon reflexes, unsteadiness, and potential psychiatric problems such as moodiness, hallucinations, delusions, and psychosis. Neuropsychiatric disorders sometimes develop independently of the anemia, particularly in elderly patients. Visual loss may develop as a result of optic atrophy. 

Salomon, RM, Miller, HL, Delgado, PL and Charney, D (1993) The use of tryptophan depletion to evaluate central serotonin function in depression and other neuropsychiatric disorders. Int. J. Clin. Psychopharmacol. 8 41-46. 

Howard, J.L., and Pollard, G.T. Are primate models of neuropsychiatric disorders useful to the pharmaceutical industry In Miczek, K.A., ed. Ethopharmacology Primate Models of Neuropsychiatric Disorders. New York Alan R. Liss, 1983. pp. 307-312. 

Lawson, W. B. (1990). Biological markers in neuropsychiatric disorders racial and ethnic factors. In E. Sorel, ed., Family, Culture, and Psychobiology. New York Levas. 

Hayashi, T., Su, T.P. Sigma-1 receptor ligands potential in the treatment of neuropsychiatric disorders. CNS Drugs. 18 269, 2004. 

Tsai G. N-acetylaspartate in Neuropsychiatric Disorders. Prog Neurobiol 1995 46 531-540. 

The SSRIs, which were initially developed as antidepressants, are now the most widely used agents in the treatment of many additional neuropsychiatric disorders... 

Thiamine deficiency results in early decreases in activity of the mitochondrial enzyme a-ketoglutarate dehydrogenase in brain. Wernicke s encephalopathy, also known as the Wernicke-Korsakoff syndrome is a neuropsychiatric disorder characterized by ophthalmoplegia, ataxia and memory loss. Wernicke s encephalopathy is encountered in chronic alcoholism, in patients with HIV-AIDS and in other disorders associated with grossly impaired nutritional status. The condition results from thiamine deficiency. 

Sapolsky, R. M. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch. Gen. Psych. 57 925-935,... 

Volumetric and morphological brain measurements are made with MRI. Modern MRI can produce detailed, high-contrast images of the entire brain in relatively short scan times with no invasive procedures or radioactivity. Thus, it is the modality of choice for detailed neuroanatomic studies in various neuropsychiatric disorders. Many groups have addressed the challenge of how to quantify subtle structural characteristics in the brain that appear to differ consistently between comparison groups. Methods such... 

Sullivan, E. V. and Pfefferbaum, A. diffusion tensor imaging in normal aging and neuropsychiatric disorders. Eur. J. Radiol. 45 244-255, 2003. 

Stanley, J. A. In vivo magnetic resonance spectroscopy and its application to neuropsychiatric disorders. Can. J. Psychiat. 47 315-326,2002. 

Screening for neuropsychiatric disorders is also important. Clinical response is more important than serum drug concentrations. 

Mercury (soft, Hg +, Hg2+) Damage to central nervous system, neuropsychiatric disorders CH3Hg+ compounds are lipid-soluble. 

C. Rohlff and K. Hollis. Modem Proteomic Strategies in the Study of Complex Neuropsychiatric Disorders. Biol. Psychiatr., 53(2003) 847-853. 

Kaye and Fainstat 1987 Wooten et al. 1983). The risk of cerebral hemorrhage is even greater when combining ephedrine with other catecholamine stimulants such as the over-the-counter stimulant phenyl-propanolamine (StoessI et al. 1985). Pseudoephedrine may be safer than ephedrine in some respects (Porta et al. 1986). In a large sample (n > 100,000) of pseudoephedrine users, there were no reports of cerebrovascular disorders within 15 days after administration. The incidence of myocardial infarction, seizures, and neuropsychiatric disorders were no greater than base rates in the general population. 

Ginsberg SD, Elarova I, Ruben M, Tan F, Counts SE, et al. 2004. Single-cell gene e3q>ression analysis implications for neurodegenerative and neuropsychiatric disorders. Neuro-... 

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