Tendon reflexes, deep

Neurological symptoms result from demyelination of the spinal cord and are potentially irreversible. The symptoms and signs characteristic of a vitamin B 2 deficiency include paresthesis of the hands and feet, decreased deep-tendon reflexes, unsteadiness, and potential psychiatric problems such as moodiness, hallucinations, delusions, and psychosis. Neuropsychiatric disorders sometimes develop independently of the anemia, particularly in elderly patients. Visual loss may develop as a result of optic atrophy. 

Leg and foot cramps, hypertension, tachycardia, neuromuscular irritability, tremor, hyperactive deep tendon reflexes, confusion, disorientation, visual or auditory hallucinations, painful paresthesias, positive Trousseau s sign, positive Chvostek s sign, convulsions Hypermagnesemia... 

Lethargy, drowsiness, impaired respiration, flushing, sweating, hypotension, weak to absent deep tendon reflexes... 

Anorexia, nausea, vomiting, mental depression, confusion, delayed or impaired thought processes, drowsiness, abdominal distention, decreased bowel sounds, paralytic ileus, muscle weakness or fatigue, flaccid paralysis, absent or diminished deep tendon reflexes, weak irregular pulse, paresthesias, leg cramps, ECG changes Hyperkalemia... 

Hypothyroidism can affect virtually any tissue or organ in the body. However, the most common symptoms, such as fatigue, lethargy, sleepiness, cold intolerance, and dry skin, are nonspecific and are seen with many other disorders. The classic overt signs, such as myxedema and delayed deep tendon reflexes, are seen uncommonly now because more patients are... 

CLL Chronic lymphocytic leukemia DTR Deep-tendon reflex... 

Acute inflammatoiy demyelinating polyneuropathy is a common cause of reversible paralysis. Acute inflammatory demyelinating polyneuropathy (AIDP), the classic form of the Guillain-Barre syndrome, often begins a week or two after recovery from cytomegalovirus, Epstein-Barr virus or Mycoplasma infection. Patients present with rapidly advancing symmetrical weakness, loss of deep tendon reflexes, often with distal numbness, and limb or back pain. Cerebrospinal fluid (CSF) protein concentration is elevated, but in most cases there is little or no increase in number of inflammatory cells in the CSF. This albumino-cytologic dissociation contrasts with the elevation of both... 

Physical signs include coarse skin and hair, cold or dry skin, periorbital puffiness, bradycardia, and slowed or hoarse speech. Objective weakness (with proximal muscles being affected more than distal muscles) and slow relaxation of deep tendon reflexes are common. Reversible neurologic syndromes such as carpal tunnel syndrome, polyneuropathy, and cerebellar dysfunction may also occur. 

Physical symptoms include dizziness, dysarthria, ataxia, nystagmus, lid ptosis, tachycardia, sweating, and increased deep tendon reflexes. Most subjects show some degree of hypertension, associated with increased minute and tidal volumes of respiration, increased formation of urine, and increased muscle tone. The latter may lead to increased serum creatinine phosphokinase concentration. With very large doses, convulsions and respiratory arrest are the terminal events (11). The course of clinical symptoms and signs following various doses of PCP is shown in Table 2. 

Lethal, 3 to 10 days respiratory depression, hypertensive crisis, cerebral bleeding, loss of deep tendon reflexes, decreased renal function, decreased liver function... 

Following the administration of an incapacitating dose of BZ, a typical sequence of events occurs. The onset is more or less insidious, with the first symptoms becoming noticeable at about one hour. Early central nervous system manifestations include heightened deep tendon reflexes, ataxia, incoordination, slurring of speech, dizziness and headache. 

Overdosage may produce extensions of the pharmacologic effects of f he drug. Excessive pressor effect, skeletal muscle hyperactivity tachycardia, and enhanced deep tendon reflexes may be early signs of overdosage. 

Blood pressure, heart rate, deep tendon reflexes... 

Long-term megadoses (2-6g over more than 2 mo) may produce sensory neuropathy (reduced deep tendon reflexes, profound impairment of sense of posifion in disf al limbs, gradual sensory af axia). Toxic sympf oms subside when drug is discon-finued. 

Musculoskeletal system Weakness and muscle fatigue increased deep tendon reflexes hypercalcemia osteoporosis Stiffness and muscle fatigue decreased deep tendon reflexes increased alkaline phosphatase, LDH, AST... 

The exactly opposite effects of drugs and dreams on pupillary aperture and reflex excitability are important examples of informative differences between the two states. REM sleep is off-line—that is, the brain is dissociated from inputs and outputs—precisely because access of afferent stimuli to the CNS is blocked (e.g., pupillary myosis), as is access of internally generated motor commands to the peripheral muscles (e.g., inhibited deep tendon reflexes). Were this not the case, REM sleep would be waking (or a hybrid state even more like drug psychosis). And if the converse were... 

Chlorzoxazone (Paraflex, Parafon Forte DSC, Others) [Skeletal Muscle Relaxant/ANS Drug] Uses Adjunct to rest physical therapy to relieve discomfort associated w/ acute, painful musculoskeletal conditions Action Centrally acting skeletal muscle relaxant Dose Adults. 250-500 mg PO tid-qid Peds. 20 mg/kg/d in 3-4 + doses Caution [C, ] Avoid EtOH CNS depressants Contra Severe liver Dz Disp Tabs SE Drowsiness, tach, dizziness, hepatotox, angioedema Interactions T Effects W/ antihistamines, CNS depressants, MAOIs, TCAs, opiates, EtOH, watercress EMS Use of CNS depressants and concurrent EtOH use can T sedation urine may turn reddish purple or orange OD May cause N/V/D, dizziness, HA, X deep tendon reflexes, hypotension and resp depression symptomatic and supportive, activated charcoal may be effective... 

Problems with memory and concentration Nystagmus Emesis Increased deep tendon reflexes Increased tremor Muscle fasciculations Death... 

Diabetic neuropathy may be associated with neuropathic ulcer, ptosis, diplopia, strabismus, loss of deep tendon reflexes, ankle drop, wrist drop, paresthesia, hyperalgesia, hyperesthesia, and orthostatic hypotension (because of autonomic dysfunction). 

Adverse effects include nausea, vomiting, alopecia, lethargy, neurologic toxicities, loss of deep tendon reflexes, and hallucinations.2 LD50 (i.v., mouse) 6.3+0.6 mg/kg LD50 (i.v., rat) 2.0+ 0.2 mg/kg.1... 

Absence of deep tendon reflexes was observed in a 22-year-old man accidentally exposed by acute inhalation to barium carbonate powder (Shankle and Keane 1988). No studies were located regarding neurological effects in animals after inhalation exposure to barium. 

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