Neural precursors

Brustle O, Spiro AC, Karram K, Choudhary K, Okabe S, McKay RD (1997) In vitro-generated neural precursors participate in mammalian brain development. Proc Natl Acad Sci USA 94 14809-14814... 

GaUi R, Binda E, OrfaneUi U, CipeUetti B, Gritti A, De Vitis S, Eiocco R, Foroni C, Dimeco F Vescovi A (2004) Isolation and characterization of tumorigenic, stem-hke neural precursors from human glioblastoma. Cancer Res 64 7011-7021... 

Soen Y, Mori A, Palmer TD, Brown PO (2006) Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol, doi 10.1038/msb4100076... 

Infusion of growth factors following an injury has been suggested to greatly enhance the replacement of lost cells. For example, infusion of EGF, the major mitogen for neural precursors, was reported to enhance the... 

On the other hand excessive synaptic release of zinc followed by entry into vulnerable neurons contributes to severe neuronal cell death. This is caused by the sequential activation of Akt and GSK-3beta, which play an important role in directing hippocampal neural precursor cell death. 

Retinoblastoma produces childhood neoplasms arising from neural precursor cells of the retina (retinoblasts) at an incidence of 1 in 20,000 live births. 

Another level of cellular adaptation to psychotropic drug exposure involves the change in neuronal number through neurogenesis. Recent research has demonstrated that in the adult hippocampus, new cells constantly arise from immature neural precursor cells in the subgranular zone of the dendate gyrus, migrate into... 

Craig, C.G., Tropepe, V., Morshead, C.M., Reynolds, B.A., Weiss, S., van der Kooy, D. (1996). In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. JNeurosci, 16, 2649-58. 

Akiyama, Y., Honmou, 0., Kato, T., Uede, T., Hashi, K., Kocsis, J.D. (2001). Transplantation of clonal neural precursor cells derived from adult human brain establishes functional peripheral myelin in the rat spinal cord. Exp Neurol, 167, 27-39. 

Armstrong, R.J., Tyers, P., Jain, M, Richards, A., Dunnett, S.B., Rosser, A.E., Barker, R.A. (2003). Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson s disease. Exp Brain Res, 151, 204-17. 

Lepore, A.C., Bakshi, A., Swanger, S.A., Rao, M.S., Fischer, I. (2005). Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Res, 1045, 206-16. 

Yan, J., Welsh, A.M., Bora, S.H., Snyder, E.Y., Koliatsos, V.E. (2004). Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord. J Comp Neurol, 480, 101-14. 

Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression. Ann Neurol, 57, 34-41. 

Hirabayashi, Y., and Gotoh, Y. (2005). Stage-dependent fate determination of neural precursor cells in mouse forebrain. Neurosci. Res. 51, 331-336. 

Seki, T., Namba, T., Mochizuki, H., and Onodera, M. (2007). Clustering, migration, and neurite formation of neural precursor cells in the adult rat hippocampus.. Comp. Neurol. 502, 275-290. 

Retroviral Vectors for Gene Delivery to Neural Precursor Cells... 

DOPAMINERGIC INNERVATION OF THE HIPPOCAMPUS AND OF THE SUBEPENDYMAL ZONE AND ROLE OF DOPAMINERGIC PROJECTIONS IN NEURAL PRECURSOR PROLIFERATION... 

Baker SA, Baker KA, Hagg T (2004) Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone. Eur J Neurosci 20 575-579. 

Bieberich E, Silva J, Wang G, Krishnamurthy K, Condie BG. Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants. J. Cell Biol. 2004 167 723-734. 

Yanagisawa M, Ariga T, Yu RK. Cholera toxin B subunit binding does not correlate with GMl expression a study using mouse embryonic neural precursor cells. Glycobiology 2006 16 19G-22G. Yanagisawa M, Ariga T, Yu RK. Fucosyl-GMl expression and amyloid-beta protein accumulation in PC 12 cells. J. Neurosci. Res. 2006 84 1343-1349. 

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