Neural precursor cells

Soen Y, Mori A, Palmer TD, Brown PO (2006) Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol, doi 10.1038/msb4100076... 

On the other hand excessive synaptic release of zinc followed by entry into vulnerable neurons contributes to severe neuronal cell death. This is caused by the sequential activation of Akt and GSK-3beta, which play an important role in directing hippocampal neural precursor cell death. 

Retinoblastoma produces childhood neoplasms arising from neural precursor cells of the retina (retinoblasts) at an incidence of 1 in 20,000 live births. 

Another level of cellular adaptation to psychotropic drug exposure involves the change in neuronal number through neurogenesis. Recent research has demonstrated that in the adult hippocampus, new cells constantly arise from immature neural precursor cells in the subgranular zone of the dendate gyrus, migrate into... 

Craig, C.G., Tropepe, V., Morshead, C.M., Reynolds, B.A., Weiss, S., van der Kooy, D. (1996). In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. JNeurosci, 16, 2649-58. 

Akiyama, Y., Honmou, 0., Kato, T., Uede, T., Hashi, K., Kocsis, J.D. (2001). Transplantation of clonal neural precursor cells derived from adult human brain establishes functional peripheral myelin in the rat spinal cord. Exp Neurol, 167, 27-39. 

Armstrong, R.J., Tyers, P., Jain, M, Richards, A., Dunnett, S.B., Rosser, A.E., Barker, R.A. (2003). Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson s disease. Exp Brain Res, 151, 204-17. 

Lepore, A.C., Bakshi, A., Swanger, S.A., Rao, M.S., Fischer, I. (2005). Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Res, 1045, 206-16. 

Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression. Ann Neurol, 57, 34-41. 

Hirabayashi, Y., and Gotoh, Y. (2005). Stage-dependent fate determination of neural precursor cells in mouse forebrain. Neurosci. Res. 51, 331-336. 

Seki, T., Namba, T., Mochizuki, H., and Onodera, M. (2007). Clustering, migration, and neurite formation of neural precursor cells in the adult rat hippocampus.. Comp. Neurol. 502, 275-290. 

Retroviral Vectors for Gene Delivery to Neural Precursor Cells... 

Yanagisawa M, Ariga T, Yu RK. Cholera toxin B subunit binding does not correlate with GMl expression a study using mouse embryonic neural precursor cells. Glycobiology 2006 16 19G-22G. Yanagisawa M, Ariga T, Yu RK. Fucosyl-GMl expression and amyloid-beta protein accumulation in PC 12 cells. J. Neurosci. Res. 2006 84 1343-1349. 

Ni HT, Hu S, Sheng WS, Olson JM, ClieeranMC, Clian AS, Lokensgai d JR, Peterson PK (2004) High-level expression of functional che-mokine receptor CXCR4 on human neural precursor cells. Brain Res Dev Brain Res 152 159—169. 

Panchision DM, Pickel JM, Studer L, Lee SH, Turner PA, Hazel TG, Mckay RD (2001) Sequential actions of BMP receptors control neural precursor cell production and fate. Genes Dev 15 2094— 2110. 

The olfactory bulb and the hippocampal dentate gyms are the only structures that display generation of neurons well into adult life. It is, however, possible to isolate neural precursor cells from the adult brain using in vitro culture systems and... 

Bartlett PF, Reid HH, Bailey KA, Bernard O (1988) Immortalization of mouse neural precursor cells by the c-myc oncogene. Proc Natl Acad Sci U S A 85 3255-3259... 

Svendsen CN, ter Borg MG, Armstrong RJ, Rosser AE, Chandran S, Ostenfeld T, Caldwell MA (1998) A new method for the rapid and long term growth of human neural precursor cells. J Neurosci Methods 85(2) 141-152... 

In Drosophila, newly formed neural precursor cells (neuroblasts and sensory organ precursors) express high levels of Delta and use Notch signaling to prevent their neighbors from becoming neural precursors (see Figure 15-38). Similar Notch-mediated lateral inhibition controls the balance between neural and non-neural cells in the development of Xenopus laevis. 

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