Need time

By plotting the cumulative resource weighting against time, the planned progress of the project can be illustrated, as shown in Figure 12.8. This type of plot Is often referred to as an S -Curve, as projects often need time to gain momentum and slow down towards completion (unlike the example shown). 

The laboratory may need time to prepare for the unit test. This must be accounted for when the test is scheduled. The analysis of... 

Undoubtedly there will already be several established performance measures some of these may be replaced with new measures. It can be important to continue these established measures, at least for a short time. This is because most people will be familiar with these measures and may need time to become comfortable with any new measures. 

These cascades of reactions need time in the range of seconds synaptic transmission through GPCRs is slow. All further postsynaptic changes depend on the type of postsynaptic cell. For example activation of 32-adrenoceptors causes in the heart an increase of the rate and force of contraction in skeletal muscle glycogenolysis and tremor in smooth muscle relaxation in bronchial glands secretion and in sympathetic nerve terminals an increase in transmitter release. 

Promoting an Optimal Response to Therapy Superficial and deep fungal infections respond slowly to antifungal therapy. Many patients experience anxiety and depression over the fact that therapy must continue for a prolonged time Depending on the method of treatment, patients may be faced with many problems during therapy and therefore need time to talk about problems as they arise Examples of problems are the cost of treatment, hospitalization (when required), the failure of treatment to adequately control the infection, and loss of income. The nurse must help the patient and the family to understand that therapy must be continued until tlie infection is under control. In some cases, therapy may take weeks or months. 

Calciothermic reduction of samarium oxide, in the presence of cobalt powder, yields samarium-cobalt alloys in the powder form. The process is popularly known as reduction diffusion. Samarium oxide, mixed with cobalt powder and calcium hydride powder or calcium particles, is heated at 1200 °C under 1 atm hydrogen pressure to produce the alloys. Cobalt oxide sometimes partly replaces the cobalt metal in the charge for alloy preparation. This presents no difficulty because calcium can easily reduce cobalt oxide. A pelletized mixture of oxides of samarium and cobalt, cobalt and calcium, with the components taken in stoichiometric quantities, is heated at 1100-1200 °C in vacuum for 2 to 3 h. This process is called coreduction. In reduction diffusion as well as in coreduction, the metals samarium and/or cobalt form by reduction rather quickly but they need time to form the alloy by diffusion, which warrants holding the charge at the reaction temperature for 4 to 5 h. The yield of alloy in these processes ranges from 97 to 99%. Reduction diffusion is the method by which most of the 500 to 600 t of the magnetic samarium-cobalt alloy (SmCOs) are produced every year. 

Cells adapt and SGs can disappear within 1 h need time course to determine optimum time... 

Considering the tremendous progress CE and related techniques have made in the last years the behavior of the authorities is difficult to understand because there is still a need of highly selective and sensitive methods for quality assessment of drugs and CE can contribute to the issue on a very high level. As already mentioned above every new technique needed time to find their way into the pharmacopoeias therefore, there is still a chance for CE. 

The first indication of ripeness will be the development of color on the skin and a few windfalls on the ground. Test by gently lifting and twisting individual fruits in the palm of your hand. Fruit of early cultivars can be eaten from the tree later cultivars need time to develop their flavor after picking. 

I just need time to be creative. I have a lot of publishing opportunities which are generated from how I work... If I am this productive with all the responsibilities that I have... imagine what I could do with more time. .. In addition to a heavy teaching load, one year I was on 13 of 15 departmental committees. This doesn t include university committees. This is ridiculous ... 

The mechanistic similarity between olefin and alkane metathesis, even if intuitive, has needed time to become obvious in the laboratory for various reasons olefin formation starting from alkanes is thermodynamically disfavored, especially at low temperature, and, as a consequence, the proposal of olefinic intermediates was not obvious. Several facts lead to the metallocarbenic mechanistic assertion ... 

Under this project, an IPCS Harmonization Project Document on the Principles of Characterizing and Applying Human Exposure has been published (WHO/IPCS 2005). This document sets out the characteristics of exposure assessment models that should be described to aid in model selection by exposure assessors. The document summarizes current practice in exposure modeling and principles for evaluating exposure models, but does not provide a comprehensive list of existing exposure models. The focus of the document is on the discussion of general properties of exposure models and how they should be described. The characteristics of different modeling frameworks are examined, and 10 principles are recommended for characterization, evaluation, and use of exposure models in order to help model users select and apply the most appropriate models. The report also discusses issues such as validation, input data needs, time resolution, and extrapolation of the model results to different populations and scenarios. 

This is an introductory book. The pace is leisurely, and where needed, time is taken to consider why certain assumptions are made, to discuss why an alternative approach is not used, and to indicate the limitations of the treatment when applied to real situations. Although the mathematical level is not particularly difficult (elementary calculus and the linear first-order differential equation is all that is needed), this does not mean that the ideas and concepts being taught are particularly simple. To develop new ways of thinking and new intuitions is not easy. 

The second set of factors is to do with the environment in which the drug finds itself It needs time to cross a membrane barrier. Less dmg may be absorbed from the gut if the patient has diarrhea with intestinal hurry (often in this situation, oral drugs may not even disintegrate fully and release their contents for absorption - visible tablets may be seen in the faeces). 

There may be several reasons for this pattern to be observed. One obvious reason is distribution, i.e. the drug needs time to reach its site of action, and the time lag between the measured drug concentration in plasma and the drug effect is due to distributional delay. In order to describe such a plasma concentration-effect relationship, a PK-PD model that allows for drug distribution to the site of action, e.g. the effect compartment model may be used. 

Finally, others will need time and space too if you are to... 

Self-counselling is an emotional as well as an intellectual process. Looking inside yourself can stir up feelings, not always comfortable ones. You may need time for your feelings to align with your intellectual understanding. 

If a patient has recently undergone surgery, the Qi and blood need time to get strong again, so pungent, very warm or very cold herbs should only be used in low doses. 

The processing procedure of using honey and dry-frying the herbs can moderate the strong functions of the aromatic and pungent herbs because it needs time to reduce heat and eliminate dampness from the Spleen. Alcohol is also used in the processing and enhances the dispersing function of the herbs to eliminate the dampness and constrained Qi. They play the roles of assistants. 

It mainly disturbs the function of the Spleen and Stomach and causes disorders of digestion and water metabolism. It has a lingering course and patients need time to recover. (See Figure... 

You hear a few individuals say, I m going to give retirement a year to see if I am ready. No part-time job. No volunteer involvement. If I discover I can t handle it, I ll come back into the labor market on a full-time basis. I need time to think, play, and gain a new perspective. I have everything to gain and little to lose. ... 

---