Microdevices

Yoo JY (2006) Recent studies on fluid flow and heat transfer in thermal microdevices. Nanoscale Microscale Thermophys Eng 10 67-81... 

Gad-el-Hak M (1999) The fluid mechanics of microdevices. The Freeman Scholar Lecture. J Fluid Eng 121 5-33... 

Gas flows are encountered in many microsystems like micro-motors, micro-turbines, micro-sensors, and microfluidic systems in the presence of air or gas environment. Since the ratio of surface area to volume increases in such microsystems, surface forces become dominant over the body forces, and gas flows have great affects on the performance and reliability of many microdevices. 

Titles K, Bund A, Plieth W, Bentien A, Paschen S, Pldttner M, Grafe H, Fischer WJ (2003) Electrochemical deposition of Bi2Te3 for thermoelectric microdevices. J Solid State Electrochem 7 714-723... 

Hessel, V., Hardt, S., Lowe, H., Chemical processing with microdevices Device/plant concepts, selected applications and state of scientific/commerdad implementation, Chem. Eng. Comm., Special edition - 6th Italian Conference on Chemical and Process Engineering, ICheaP-6 3 (2003) pp. 479-484. 

Lamouille, T., Grenouillet, P., High-throughput kinetic investigations of asymmetric hydrogenations with microdevices, Adv. Synth. Catal. 345, l-t2 (2003) 190-193. 

DE Belleeon, C., Application of microdevices for the fast investigation of catalysis, in Proceedings of the Micro Chemical Plant - International Workshop, pp. L3 (9-17) (4 Eebruary 2003), Kyoto, Japan. 

Tu, J. K., Huen, T., Szema, R., Ferrari, M., Filtration of sub-100 nm particles using a bulk-micromachined, direct-bonded silicon filter, J. Biomed. Microdevices 1 (1999) 113-119. 

BesserJI.S.BortJ.Burangalikar, H.,Ouyang3., Microdevice-basedsystem forrapidcatalystdevelopment, in MatloszM.BhreeldWBaseltJ.P. 

High-throughput screening of molecular catalysts using automated liquid handling, injection and microdevices, Ghimia 56, 11 (2002) 621-626. 

Flytzanis, C., Hache, F, Ricard, D., Roussignol, Ph. in The Physics and Fabrication of Microstructures and Microdevices (eds. Kelly, M. J., Weisbuch, C.) Springer-Verlag Berlin 1986... 

Schmalzing, D., Koutny, L., Chisholm, D., Adourian, A., Matsudaira, P, and Ehrlich, D., Two-color multiplexed analysis of eight short tandem repeat loci with an electrophoretic microdevice, Anal. Biochem., 270, 148, 1999. 

H. Dong, C.M. Li, Q. Zhou, J.B. Sun, and J.M. Miao, Sensitive electrochemical enzyme immunoassay microdevice based on architecture of dual ring electrodes with a sensing cavity chamber. Biosen. Bioelectron. 22, 621-626 (2006). 

L. Nihlen and H. Capps, Nanolaser/microfluidic biochip for realtime tumor pathology. Biomedical Microdevices 2, 111-122 (1999). 

Recent trends are focused on the use of micromaching techniques to form miniaturized capillary geometries in planar microdevices. These superminiaturized sys-... 

In the context of this paper, only the microdevices and the micropro-cess engineering for uses in tine chemistry and pharmacy are considered. The view will be process-based and deduced from a rough economic calculation of how mature the technology is and what needs to be done to promote it further. 

The latest advancement in femtosecond (fs)-based micromachining technology has opened a new window of opportunity for fabrication of microdevices. Direct exposure of most solid materials (including fused silica glass) to high power fs laser pulses may lead to the ablation of a thin layer of materials at the laser focal point13. Due to the multiphoton nature of the laser-material interaction, the ablation process can be conducted on the material surface as well as within its... 

Ilic, B. Craighead, H. G., Topographical patterning of chemically sensitive biological materi als using a polymer based dry lift off, Biomed. Microdevices 2000, 2, 317 322... 

Stoltenberg RM, Woolley AT (2004) DNA-templated nanowire fabrication. Biomed Microdevices 6 105-111... 

Chip-based microdevices are finally discussed, regarding fabrication methods, designs, MS interfacing, and applications. Current capabilities and limitations for future use are emphasized considering improvements in methodology and instrumentation. 

Microchips fabrication with integrated tips can result in improved spray repeatability and efficiency since alignment and dead volume are not a critical issue anymore. However, production of fine and robust nanospray emitters as an integral part of a microdevice is not trivial, and highly specialized microfabrication procedures are required. Microfluidic devices with integrated ESI tips have been produced for infusion experiments, but to date, no microchips with such a design was fabricated for CE separation prior to MS detection. 

Zhang, B., Foret, F, and Karger, B. L. (2000). A microdevice with integrated liquid junction for facile peptide and protein analysis by capillary electrophoresis/electrospray mass spectrometry. Anal. Chem. 72, 1015-1022. 

Three-dimensional batteries offer a different approach to the portable power field. In this paper we have presented 3-D designs that emphasize power sources with small areal footprints but do not compromise power and energy density. While this approach may not help solve the power needs for cell phones and laptop computers, it will have a significant impact on current and future generations of microdevices. In particular, distributed sensor networks and wireless communication systems are representative areas where 3-D batteries would be welcomed enthusiastically because the power supplies currently in use are many times the size of the device. 

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