N-Butyl methyl carbinol

Methyl n-butyl ketone Methyl n.butyl carbinol... 

Use the apparatus detailed in Section 111,20. Dissolve 100 g. (123 ml.) of methyl n-butyl ketone (2-hexanone) (Section 111,152) in 750 ml. of ether and add 150 ml. of water. Introduce 69 g. of clean sodium in the form of wire (or small pieces) as rapidly as possible the reaction must be kept under control and, if necessary, the flask must be cooled in ice or in running water. When all the sodium has reacted, separate the ethereal layer, wash it with 25 ml. of dilute hydrochloric acid (1 1), then with water, dry with anhydrous potassium carbonate or with anhydrous calcium sulphate, and distil through a fractionating column. Collect the fraction of b.p. 136-138°. The yield of methyl n-butyl carbinol (2-hexanol) is 97 g. 

Methyl n-amyl carbinol from methyl n-amyl ketone) Methyl n-butyl carbinol from methyl n-butyl ketone) Methyl t o-propyl carbinol Di-n-butyl carbinol from n-butyl bromide)... 

Methyl n-amyl carbinol. 247, 254 Methyl n-amyl ketone, 482 Methylaniline (mono), pure, from commercial methylaniline, 562, 570 P-Methylanthraquinone, 728, 740 Methyl benzoate, 780, 781 p-Methyl benzyl alcohol, 811,812 Methyl benzyl ketone, 727, 735 Methyl y-bromocrotonate, 926, 927 2-Methyl-2-butene, 239 Methyl n-butyl carbinol, 247,255 Methyl n-butyl ether, 314 Methyl n-butyl ketone, 475, 481 4-Methylcarbostyril, 855 p-Methylcinnamic acid, 719 4-Methylcoumarin, 853, 854 Methyl crotonate, 926, 927 Methylethylacetic acid, 354, 358 Methylethylethynyl carbinol, 468 Methyl ethyl ketone, 335, 336 purification of, 172 Methyl n-hexyl ether, 314 Methyl n-hexyl ketone, 335, 336 Methyl n-hexyl ketoxime, 348 Methyl hydrogen adipate, 938 Methyl hydrogen sebacate, 938,939 4-Methyl-7-hydroxycoumarin, 834 Methyl iodide, 287 Methyl isopropyl carbinol, 247,255 Methyl 4-keto-octanoate, 936... 

Methyl n-ptopyl carbinol (6) Cetyl alcohol (11) Ethyl celloBOlve (16) Butyl carbitol ... 

Monobasic solutes that have no carbinyl hydrogens may also show nonequivalence. 3-Methyl-2-butanone, 4-methyl-2-pentanone, 2-methylpropanal, methyl 2-methylbutyrate, 2,2,6,6-tetramethyl-piperidine, methyldiisopropylcarbinol, and methylethyl-n-butyl-carbinol in TFAE-saturated benzene all show nonequivalence of sufficient magnitude (0.01-0,03 ppm) to allow nonequivalence sense determination at 220 MHz. An especially striking example is that provided by pyrazolines 26. With only a severalfold excess of (S)-TFAE, 3(5),5(S)-enriched samples of these compounds show nonequivalence in their methyl resonances (downfield sense for the singlets and upfield sense for the triplets) sufficient for enantiomeric purity determination at 90 MHz (52). 

Ethyl sec-amyl ketone, see 5-Methyl-3-heptanone Ethylbenzol, see Ethylbenzene Ethyl butyl ketone, see 3-Heptanone Ethyl n-butyl ketone, see 3-Heptanone Ethyl carbinol, see 1-Propanol Ethyl cellosolve, see 2-Ethoxyethanol Ethyl chloride, see Chloroethane Ethylcyclopentan, see Ethylcyclopentane Ethyldimethylmethane, see 2-Methylbutane Ethylendiamine, see Ethylenediamine Ethylene aldehyde, see Acrolein Ethylene bromide, see Ethylene dibromide Ethylene bromide glycol dibromide, see Ethylene dibromide... 

B.19) (B.19) 2-Hexanol, hexan-2-ol, sec-hexyl alcohol, n-butyl methyl carbinol [626-93-7] ... 

Alkyl and aryl groups have a stabilising effect on the cyclopropenium cation, the former being the more effective, e.g. p g+ values for the tri-n-propyl and triphenyl derivatives are, respectively, 7,2 and 0.5 [5]. Of a series of trialkylcyclopropenium salts the plfg+ values indicated stabilities in the order methyl > n-propyl > isopropyl t-butyl [27]. This order is not that to be expected solely from a consideration of inductive effects. Steric factors may play a role in that vicinal crowding is lessened when the carbinol is formed ... 

Methanol Ethanol Isopropanol n-Propanol n-Butyl alcohol Isobutanol Mixed amyl alcohols 3-Methoxy butanol Pentanol-3 Methyl amyl alcohol 2-Ethylbutanol n-Hexanol Heptanol-3 2-Ethylhexanol Diisobutyl carbinol Trimethyl nonyl alcohol Undecanol Tetrad ecanol Heptadecanol Trimethyl cyclohexanol T etrahy dropy ran-2-methanol... 

Butyl methyl carbinol n-Butyl methyl carbinol. See 2-Hexanol... 

Synonyms Active amyl alcohol Active primary amyl alcohol Amyl alcohol, active dl-s-Butylcarbinol s-Butyl carbinol 2-Methyl butanol 2-Methyl butanol-1 2-Methyl-n-butanol ( )-2-Methyl-1-butanol 2-Methylbutyl alcohol Primary active amyl alcohol Classification Primary aliphatic alcohol Empirical C5H12O Formula CH3CH2CH(CH3)CH20H Properties Colorless liq. sour sharp odor m.w. 88.15 very sol. in acetone sol. in alcohols, ether si. sol. in water m.w. 88.15 dens. 0.816 (20 C) vapor pressure 2.0 mm Hg (20 C) f.p. < -70 C b.p. 128 C flash pt. (TCC) 43 C surf. tens. 25.7 dynes/cm (20 C)... 

The search for opioid analgesics which show reduced addiction liability ha.s centered largely on benzomorphan and morphinan derivatives. Some research has, however, been devoted to derivatives of the structurally simpler meperidine series. The preparation of one such compound, picenadol (59), starts with the reaction of N-methyl-4-piperidone with the lithium derivative from m-methoxybromobenzene. Dehydration of the first formed carbinol 51 gives the intermediate 52. Deprotonation by means of butyl lithium gives an anion which can be depicted in the ambident form 53. In the event, treatment of the anion with propyl bromide gives the product 54 from reaction of the benzylic anion. Treatment of that product, which now contains an eneamine function. 

An interesting case of interproduct competition is that of the four original lacquer solvents—ethyl alcohol, butyl alcohol, ethyl acetate, and butyl acetate. These were once produced mainly by fermentation processes, but today all are also produced by synthesis from petroleum hydrocarbons. Moreover, in the past 30 years solvents have been developed from petroleum sources which are competing successfully with these materials even though the new compounds are not identical in all properties isopropyl alcohol competes with ethyl alcohol methyl isobutyl carbinol and n-propyl alcohol can replace butyl alcohol methyl ethyl ketone to a large extent supplants ethyl acetate and methyl isobutyl ketone can be substituted for butyl acetate. Thus, petroleum aliphatic chemicals have served both by displacement of source and replacement of end product to supplement and to compete with the fermentation solvents. 

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