Matrix-assisted laser desorption-ionization MALDI mass spectroscopy

Mass spectroscopy is a useful technique for the characterization of dendrimers because it can be used to determine relative molar mass. Also, from the fragmentation pattern, the details of the monomer assembly in the branches can be confirmed. A variety of mass spectroscopic techniques have been used for this, including electron impact, fast atom bombardment and matrix-assisted laser desorption ionization (MALDI) mass spectroscopy. [Pg.138]

By using matrix-assisted laser desorption/ionization (MALDI) mass spectroscopy, Yokozawa and coworkers were able to investigate in detail the polymer... [Pg.165]

Abbreviation MALDI, matrix-assisted laser desorption-ionization MS, mass spectroscopy LC, liquid chromatography POMC, proopiomelanocortin... [Pg.25]

Three techniques have been mainly utilized to characterize gold clusters, namely mass spectroscopy, high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), and extended X-ray absorption fine structure spectroscopy (EXAFS). For unsupported gold clusters, electrospray ionization (ESI) mass spectrometry and matrix-assisted laser desorption ionization (MALDI) mass... [Pg.405]

Mass spectra are used to determine molecular weights and molecular composition (from the parent or molecular ion) and to obtain structural information from the fragmentation of the molecular ion into daughter ions. Electrospray ionization (ESI-MS) and matrix-assisted laser desorption ionization (MALDI-MS) mass spectroscopy can be used to obtain structural information about macromolecules, including proteins, polymers, and drug-DNA complexes. [Pg.233]

Moreover, the typical tools of supramolecular chemistry, such as NMR spectrometry, require concentrations usually in excess of 10 " mol/1. and other favorite methods such as mass spectroscopy [fast-atom bombardment (FAB), electrospray ionization (ESI), matrix-assisted laser desorption ionization (MALDI)], and vapor-pressure os-moinetry do not directly provide information about supramolecular behavior in solution. The most favorite method, x-ray analysis, suffers from the limitation posed by the ultimate requirement of being able to grow single crystals. While this is. in numerous instances, possible in the case of pure molecular entities, supramolecules, being mixed molecular objects by nature, are usually difficult to grow in the form of a single crystal. [Pg.1060]

The molecular weights and molecular weight distributions (MWD) of phenolic oligomers have been evaluated using gel permeation chromatography (GPC),23,24 NMR spectroscopy,25 vapor pressure osmometry (VPO),26 intrinsic viscosity,27 and more recently matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).28... [Pg.385]

Considering these situations, the observation of molecular weights, particularly by matrix-assisted laser desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF MASS), is essential [33]. The operation is simple and enables us to observe the molecular ion peaks of CPOs with molecular weights exceeding 10,000. The quahty of the measurement is strongly dependent on the choice of the matrix. Therefore, the search for the best matrix for each CPO should be pursued. [Pg.80]

MALDI MCM-41 MCR MD ME MEM MI MPM MRI MS MVA Matrix-assisted Laser Desorption/Ionization Mobile Crystalline Material-41 Multivariate Curve Resolution Molecular Dynamics Matrix-enhanced Magnetic Force Micrscopy Multivariate Image Multiphoton Microscopy Magnetic Resonance Imaging Mass Spectroscopy Multivariate Analysis... [Pg.219]

The low volatility of ILs makes them useful as solvents working under high vacuum, and together with their more amorphous solid analogs they are convenient in matrix-assisted laser-desorption/ ionization-mass spectroscopy (MALDI-MS) analysis.103104... [Pg.361]

Dendrimer characterization was accomplished by 13C, NMR and FT-IR spectroscopy as well as mass spectrometry using fast atom bombardment (FAB) and matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) techniques. Molecular ion base peaks were observed in the MALDI-TOF MS of polyester 168 (mlz 18900 (calcd. 19044)) along with minor peaks at 37000 and 54000 mlz corresponding to ionic gasphase dimer and trimer complexes. [Pg.94]

MALDI-MS refers to matrix-assisted laser desorption-ionization mass spectroscopy, It is also called MALFI-TOF, because the mass spectrometer is a time-of-flight version. In this technique, the polymer is mixed with a molar excess of a salt, for cationization, and deposited on a probe surface. A UV laser is pulsed... [Pg.113]

Matrix-assisted laser-desorption ionization time-of-fiight (MALDI-TOF) mass spectrometry can be used to detect sequence polymorphisms. With mass spectroscopy, no label is necessary because the alleles differ in mass. After... [Pg.1429]

SEC, size exclusion chromatography. MALDI-TOF-MS, matrix-assisted laser desorption/ ionization time-of-flight mass spectroscopy. [Pg.26]

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