Macrophylla

Alstonia macrophylla Wall. Villalstonine, macralstonine, macral-... 

Ba e M. This substance, which is present in traces in A. macrophylla, has only been obtained as a crystalline sulphate, m.p. about 257°, [ajo - 71-9° (H2O). 

M. stipulosa Kuntze (M. macrophylla Hiern). Rhyncophylline. Ourouparia formosana Mats. Formosanine. ... 

Hydrangea Hydrangea macrophylla. Michigan State University Extension, http //www.msue.msu.edu/msue/imp/mod10/10000171. html... 

AKIYAMA, T SHIBUYA, M., LIU, H.M., EBIZUKA, Y. p-Coumaroyltriacetic acid synthase, a new homologue of chalcone synthase, from Hydrangea macrophylla var. thunbergii, Eur. J. Biochem., 1999, 263, 834-839. 

Five isobutylamides were isolated as insect growth inhibitors and toxicants from Fagara macrophylla and identified from their spectroscopic and chemical data. Synthesis and bioassay of the five natural products plus four analogs showed pellitorine to be the most active against a variety of insects, but not against a species of snail. 

Biologically active isobutylamides have been isolated from plants of the Compositae and the Rutaceae. Some of the isohutyla-mides were found to have paralytic and toxic activities against insects, especially when applied topically to several species of Coleopterans and Dipterans.The present work describes the isolation, spectral identification, synthesis, and insect and snail bioassays of five isobutylamides from the Rutaceae plant, Fagara macrophylla. In addition, the synthesis and bioassay of four analogs of the isbbutylamide natural products are described. 

F. macrophylla is an East African medicinal tree known to be relatively free from insect attack. In order to test for chemical factors involved in this observed resistance, pieces of root bark were extracted with methanol, followed by evaporation of the methanol and suspension of the extract in water. A chloroform extraction of the suspension was chromatographed on silica gel 60 (30-70 mesh ASTM) in methylenechloride-methanol. 

Therefore, we conducted additional bioassays of four of the F. macrophylla isobutylamides with the house mosquito, Culex pipiens and the freshwater snail, Biomphalaria glabratus (Tables II, III). Both species are of medical importance. 

While the F. macrophylla isobutylamides, especially pellitorine, are active against several species of pest organisms of medical and agricultural importance, their activity must be enhanced before they can be used on a commercial basis. Hopefully, the results of the present work will direct future studies leading to synthetic isobutylamides of sufficient activity to warrant their practical use in insect and snail control. 

Apocynaceae Alstonia macrophylla Talcarpine Pleiocarp amine Alstoumerine 2-O-epiantirhine Alstonerine Alstophyline Macralstonine Alstomacrophyline Villalstonine Alstomacroline Macrocarpamine... 

Keawpradub, N., Eno-Amooquaye, E., Burke, P. J. and Houghton, P. J. 1999. Cytotoxic activity of indole alkaloids from Alstonia macrophylla. Planta Medica, 65 311-315. 

Most recently a series of piperidinyl-flavonoid alkaloids have been isolated from two Buchenavia spp. (Combretaceae) (6). The leaves of B. macrophylla Eichl. yielded buchenavianine (8) and iV-demethylbuchenavianine (9). The fruits... 

CS103 Chaboud, A., J. Rayaud, L. Debourcieu and J. Reynaud. The presence of apigenin-2 -0-glucosyl-6-C-glucosylapigenin or 2 -)-glucosylisovi-texin in the leaves of Thea sinensis Sims. var. macrophylla. Pharmazie 1986 41(10) 745-746. 

CS156 Chaboud, A., ]. Raynaud and L. Debourcieu. 6,8-Di-C-beta-D-arabino-pyranosyl apigenin from Thea sinensis var. macrophylla. J Nat Prod 1986 49(6) 1145. 

Sesquiterp. dimers elemane/eudesmane macrophyilidimer A and dimeric elemane Inula macrophylla from Uzbekistan Su 2000). 

Kondo, T. et al.. Cause of flower color variation of hydrangea, Hydrangea macrophylla, Tennen Yuki Kagobutsu Toronkai Koen Yoshishu, 41, 265, 1999. 

Six new flavanones having one or more C-benzyl groups attached to C-6 or C-8, or both, have been reported from members of the Annonaceae, a family from which many C-benzylated flavanones and dihydrochalcones had previously been described. The new compounds (212-217) are presented in Table 15.6. Macrophyllol (212) and macrophyllol A (213, Figure 15.6) have been isolated from the roots of Uvaria macrophylla. These consist of 5-hydroxy-6,7-dimethoxyflavanone with one 2-hydroxy-5-methoxybenzyl unit attached to C-8 and C-6, respectively. The roots of Xylopia africana yielded isouvarinol (214, Figure 15.6), in which one 2-hydroxybenzyl unit is attached to C-6 and two units to C-8. Its... 

Macrophyllol A (Figure 15.6) Uvaria macrophylla Annonaceae Root 164... 

Tan, R.X. et al.. Acyl secoiridoids and antifungal constituents from Gentiana macrophylla. Phytochemistry, 42, 1305, 1996. 

Zhang, FI.L. and Chen, R.Y., A new flavanone from the roots of Uvaria macrophylla. Chin. Chem. Lett., 12, 791, 2001. 

Lin, L.J. et al.. Traditional medicinal plants of Thailand. Part 18. 6-Deoxyclitoriacetal from Clitoria macrophylla. Phytochemistry, 31, 4329, 1992. 

Alstonia macrophylla Wall, ex G. Don / stem EtOH/ Maceration Sweroside, naresuanoside [128]... 

Preparative chromatography was performed with thin layer chromatography (TLC) aluminum sheets and 8 2 chloroform/ methanol as mobile phase of a fraction from the 95% EtOH extract of stems of Alstonia macrophylla. This procedure led to the isolation of the compounds sweroside (2 mg) and naresuanoside (3 mg) [128]... 

Changwichit K, Khorana N, Suwanborirux K, Waranuch N, Limpeanchob N, Wisui-tiprot W, Suphrom N, Ingkaninan K. Bisindole alkaloids and secoiridoids from Alsto-nia macrophylla Wall, ex G. Don. Fitoterapia 2011 82(6) 798-804. 

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