Lewis lung cancer cells

Rat mammary tumors Lewis lung cancers Mouse mammary tumors Choriocarcinoma cells Anaplastic sarcomas Walker carcinoma cells Rat prostatic carcinomas Rat embryo fibroblasts Different malignant cells... 

Intercedensides A (90), B (91) and C (92) from Mensamaria intercedens collected in South China Sea showed cytotoxicity against 10 human tumor cell lines with ED50 in the range 0.6-4.0 pg/ml (Table 10) [74]. Glycoside 90 exibited antineoplastic activity in vivo against mouse Lewis lung cancer and mouse S 180 sarcoma. 

Lewis Y antigen BC8-F3 Difucosylated tetrasaccharide found on type 2 blood group oligosaccharide SK-LU-3 lung cancer cell line Signet 1 40 HIER... 

O Reilly MS et al. (1994) Angiostatin a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79(2) 315-328 Overgaard J et al. (2005) Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer results from the DAHANCA 5 randomised double-blind placebo-controlled trial. Lancet Oncol 6(10) 757-764... 

Heike Y, Takahashi M, Ohira T, et al. Genetic immunotherapy by intrapleural, intraperitoneal and subcutaneous injection of IL-2 gene-modified lewis lung carcinoma cells. Int J Cancer 1997 73 844-849. 

Gerard [102] was one of (he first investigatoo to use high doses of bromelain alone or in combination with other chemotherapeutic agents on cancer patients. There ant. however, few controlled studies enneerninv the beneficial effect f bromelain an various tumors. In vitro studies on three cell lines—Lewis lung carcinoma, YC lymphoma, and MCA-1 ascitic tumor—allowed that bromelain... 

Within the last 10 years a great number of plants have been screened for antitumour active alkaloids. The two major groups involved in this search were the National Cancer Institute and a group of chemists and biologists at Eli Lilly and Co. Crude extracts and crystalline alkaloids were screened in vitro (cell cultures) and in vivo against sarcoma 180, Walker 256 intramuscular carcinosarcoma, Eagle s K.B. strain of human carcinoma of the nasopharynx, Lewis lung carcinoma, etc. The tests, which were reproducible, were made under standard conditions set up by the C.C.N.S.C. (Cancer Chemotherapy National Service Centre). 

Many reports indicate that malignant cancer cells express carbohydrate antigens other than sLe and sLe antigens. These reports show a correlation between expression of particular cell surface carbohydrate antigens and poor prognosis in cancer patients (104,105). Examples of these are seen in Lewis B (Le ) and Lewis Y (Le ) antigens overexpressed by breast, lung, ovarian, and endometrial cancers (104,106-110). 

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