Brain disease and

A 75-year-old white man, without a history of psychiatric disorders, took cortisone 50 mg/day for 6 weeks for pulmonary fibrosis and developed severe obsessive-compulsive behavior without affective or psychotic symptoms. He was given risperidone without any beneficial effect. The dose of cortisone was tapered over 18 days. An MRI scan showed no signs of organic brain disease and an electroencephalogram was normal. His symptoms improved 16 days after withdrawal and resolved completely after 24 days. Risperidone was withdrawn without recurrence. 

Loscher W, Potsclika H (2005a) Drug resistance in brain diseases and tlie role of drag efflux ri ansporters. Nat Rev Neurosci 6 591-602. 

The Standard American Diet truly is SAD when it comes to preventing disease and maintaining great health. Our excessive consumption of fast food, sugar, trans fats, meat, and food additives is the fast track to disease. We need to make simple changes to break free of the Standard American Diet or risk suffering one or more of the many diseases finked to it, including obesity, heart disease, brain disease, and many forms of cancer. 

Loscher. W. and Potschka, H. (2005) Drug resistance in brain diseases and the role of drug efflux transporters. Nature Reviews. Neuroscience, 6 (8), 591-602. 

Addiction is a brain disease, and it matters . A series of articles in Science 1997 278 45-70 Altman J, Everitt B J, Glautier S et al. The biological, social and cUnical bases of drug addiction commentary and debate. Psychopharmacology 1996 125 285-345 Ashton CH. Pharmacology and effects of cannabis a brief review. Br J Psychiatry 2000 178 101-... 

Theodor Meynert (1833-1892), one of the founders of modern neuropsychiatry, began his textbook Psychiatry (1884), with this statement The reader will find no other definition of Psychiatry in this book but the one given on the title page Clinical Treatise on Diseases of the Forebrain. The historical term for psychiatry, i.e., treatment of the soul, implies more than we can accomplish, and transcends the bounds of accurate scientific investigation. Meynert postulated that mental diseases are brain diseases and predicted that psychiatry would merge into the study of the lesions of the frontal lobe and its connections. 

Today, psychiatrists are divided between those who endorse the scientific definition of disease and claim that mental illnesses are brain diseases, and those who reject or ignore that definition and instead boldly embrace criteria for what counts as illness completely unrelated to it. The views of Lawrie Reznek, author o( A Philosophical Defence of Psychiatry, exemplify the latter approach. He writes Whether we ought to punish serial killers or treat them is not something that depends on the facts Ifwe feel we ought to treat psychopaths, then they are ill. Ifwe feel they should be punished, they are not-It is... 

Baby LW was given a dose of morphine which was 100 times stronger than it should have been. The death certificate said Baby LW died from a brain disease and breathing difficulties. 

Thiamine deficiency results in an impairment of oxidative metabolism. The consequences of this include a series of events that set the stage for cerebral vulnerability. While thiamine deficiency and Wernicke s encephalopathy involve a variety of functional impairments at several different levels, understanding the mechanisms that underlie the characteristic focal vulnerability associated with this disorder remains a major challenge and is expected to continue to yield important new insight into how metabolic brain disease and neurodegeneration are interrelated. 

D. E. K. Sutherland and M. J. Stillman, Mammalian MetaUothioneins, in Brain Diseases and Metalloproteins, ed. D. R. Brown, CRC Press, 2012, p. 81. A. Suzuki and T. Oku, Electronic Stmcture and Magnetic Properties of NdJCgo - SWCNT, in Electronic Properties of Carbon Nanotubes, ed. 

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