Idiosyncrasy

That the rate profiles are close to parallel shows that the variations in rates reflect the changing concentration of nitronium ions, rather than idiosyncrasies in the behaviour of the activity coefficients of the aromatic compounds. The acidity-dependences of the activity coefficients of / -nitrotoluene, o- and -chloronitrobenzene (fig. 2.2, 2.3.2), are fairly shallow in concentrations up to about 75 %, and seem to be parallel. In more concentrated solutions the coefficients change more rapidly and it... 

This monograph could not have been produced without the expert assistance of Mr David Clarke who has spent many hours to load the necessary fonts in the computer, and for advising one of the authors (W.L.F.A.) on how to use them together with the idiosyncrasies of Microsoft Word. 

Of the other cinchona bases, the dextrorotatory forms cinchonine and quinidine have been used as anti-malarial drugs in cases of idiosyncrasy to quinine, a subject to which Dawson has given much attention. Quinidine is used to eontrol auricular fibrillation, and its value for this purpose in comparison with dihydroquinidine has been investigated by several workers. Dawes has recently devised a method of testing... 

During these past few decades, the bicycle itself has vastly improved. The bicycles of the early 1970s usually had mechanical idiosyncrasies. Competition among manufacturers, led by the Japanese companies that entered the U.S. market, resulted in vastly improved quality control. The mountain bike, first made available on a widespread basis m 1983, offered a delightful alternative that mushroomed in popularity, and a decade later, traditional road bicycles had all but disappeared from stores. The mountain bike has become most people s vehicle of choice for city riding as well as recreational trail riding. 

Attempting to modify structure or services to accommodate structural idiosyncrasies later is always problematic. Protection and isolation of existing facilities from the disruption of construction should be resolved early in the design. The reconciliation of building and production activities is never easy, but early planning for construction traffic, personnel, site screening, security, site access and site communications can minimize these adverse effects. 

Define drug tolerance, cumulative drug effect, and drug idiosyncrasy. 

The cause of drug idiosyncrasy is not clear. It is believed to be due to a genetic deficiency that makes the patient unable to tolerate certain chemicals, including drugs. 

Drug reactions are potentially serious. The nurse should observe all patients for adverse drug reactions, drug idiosyncrasy, and evidence of drug tolerance (when applicable). It is important to report all drug reactions or any unusual drug effect to the primary health care provider. 

This drug is used for complete or partial reversal of narcotic depression, including respiratory depression. Narcotic depression may be due to intentional or accidental overdose (self-administration by an individual), accidental overdose by medical personnel, and drug idiosyncrasy Naloxone also may be used for diagnosis of a suspected acute opioid overdosage. 

D Ineffective Airway Clearance related to administration of a narcotic (specify overdose, drug idiosyncrasy, or other cause)... 

However, responses to administration of a cholinergic blocking drug vary and often depend on the drug and the dose used. For example, scopolamine may occasionally cause excitement, delirium, and restlessness. This reaction is thought to be a drug idiosyncrasy (an unexpected or unusual drug effect). 

Placing a list of known or suspected drug allergies or idiosyncrasies on the front of the chart. 

Type B not related to dose, not generally predictable, likely to have an immunological basis or related to a metabolic idiosyncrasy. 

Recent investigations have reduced some disease states from an idiosyncrasy of unknown etiology to a well-defined metabolic disorder due to enzymatic deficiencies with appropriate therapeutic conclusions. 

Palladium chemistry of heterocycles has its idiosyncrasies stemming from their different structural properties from the corresponding carbocyclic aryl compounds. Even activated chloroheterocycles are sufficiently reactive to undergo Pd-catalyzed reactions. As a consequence of a and y activation of heteroaryl halides, Pd-catalyzed chemistry may take place regioselectively at the activated positions, a phenomenon rarely seen in carbocyclic aryl halides. In addition, another salient peculiarity in palladium chemistry of heterocycles is the so-called heteroaryl Heck reaction . For instance, while intermolecular palladium-catalyzed arylations of carbocyclic arenes are rare, palladium-catalyzed arylations of azoles and many other heterocycles readily take place. Therefore, the principal aim of this book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. 

Legacy adapter This thin layer shields business objects from idiosyncrasies of the legacy system and its representations. 

Variability in responses to drugs has been observed as long as drugs have been tested systematically. These variations have been designated as "biological" and have been considered a necessary evil by those who have sought to develop a systematic science of pharmacology. Much attention has been paid to the mathematical treatment of the data obtained from such tests, but little to the basic reasons for the variability. Krantz and Carrl state frankly "The mechanism of idiosyncrasy is not understood."... 

Avoid the reactions observed in the past Till all at length are free From vexing idiosyncrasy. 

Taste idiosyncrasies (for example, the dislike of butter) are related no doubt to taste sensitivities, and according to Davenport47 there is evidence that such dislikes are inherited. 

Our sample began with the top 1,000 economic-value-added (EVA) companies for 2002 based upon Stern Stewart s MVA database and methodology. We then eliminated banks, diversified financials, REITs, and insurance companies because of accounting and industry idiosyncrasies. 

Within any computerised system the physicians involved are a fixed group with its own idiosyncrasies and limitations in number. 

Hypersensitivity or idiosyncrasy to quinidine or other cinchona derivatives manifested by thrombocytopenia, skin eruption or febrile reactions myasthenia gravis history of thrombocytopenic purpura associated with quinidine administration digitalis intoxication manifested by arrhythmias or AV conduction disorders complete heart block left bundle branch block or other severe intraventricular conduction defects exhibiting marked QRS widening or bizarre complexes complete AV block with an AV nodal or idioventricular pacemaker aberrant ectopic impulses and abnormal rhythms due to escape mechanisms history of drug-induced torsade de pointes history of long QT syndrome. 

Advanced arteriosclerosis symptomatic cardiovascular disease moderate to severe hypertension hyperthyroidism hypersensitivity or idiosyncrasy to the sympathomimetic amines glaucoma agitated states history of drug abuse during or within 14 days following administration of monoamine oxidase (MAO) inhibitors (hypertensive crises may result). 

Injection - Heart failure secondary to chronic lung disease cardiac arrhythmias brain tumor acute alcoholism delirium tremens idiosyncrasy to the drug increased intracranial or CSF pressure head injuries acute bronchial asthma upper airway obstruction. Because of its stimulating effect on the spinal cord, morphine should not be used in convulsive states (eg, status epilepticus, tetanus, strychnine poisoning) concomitantly with MAOIs or in those who have received such agents within 14 days. 

Concomitant conditions Use with caution in the following patients exposed to extreme heat or phosphorus insecticides atropine or related drugs because of additive anticholinergic effects those in a state of alcohol withdrawal those with dermatoses or other allergic reactions to phenothiazine derivatives because of the possibility of cross-sensitivity those who have exhibited idiosyncrasy to other centrally acting drugs. 

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