I Propionic acid

Dextro- 3-(4-hydroxyphenyl)-0 -pheny I propionic acid Iodine... 

A mixture of 100 g of ethyl 2-cyano-2-(5H-[ 1 ] benzopyrano [2,3-b] -py rid in-7-y I [propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate Is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1] benzopyrano [2,3-b] -pyridin-7-y I [propionic acid as white crystals melting at 183°Cto 183.5°C. 

Iso-leucine, (CHr-CH2)—CH—CH(NH2)—COOH, a-Amino /3-Efhyl /3-Methyl I Propionic Acid... 

The main conclusions to be drawn from these investigations are that d(-I-) propionic acids have a stronger auxin activity than the corresponding acetic acids, while l(-) propionic acids have a marked antiauxin action. 

Reagents and conditions i) propionic acid, A ii) continuous extraction iii) K2CO3, MeOH. 

Adsorption from the four-component mixture acetic acid-I-propionic acid + butyric acid-I-cyclohexane by ASK silica gel is reported on by Gryazev et G.l.c. was used for the analysis of the equilibrium solutions and the experiments were based on a simplex-grid design. 

Lactisole [13794-15-5] the sodium salt of racemic 2(4-methoxyphenoxy)propionic acid, is a sweet-taste inhibitor marketed by Domino Sugar. It was affirmed as a GRAS flavor (FEMA no. 3773). At a concentration of 100 to 150 ppm, lactisole strongly reduces or eliminates the sweet taste of a 10% sugar solution. This inhibition appears to be receptor-related because lactisole also inhibits the sweet taste of aspartame. The 5 -( —)-enantiomer [4276-74-8] (38), isolated from roasted coffee beans, is the active isomer the i -(+)-enantiomer is inert (127). 

A large number of thyroid hormone analogues have been tested for this effect (6). Among others, i-T (3) and 3,3 -T2 (5) and their propionic acid side-chain analogues decrease oxygen consumption at molar ratios of 50—200 1 of T. Nevertheless, no potent or clinically usehil peripheral antagonists have been found. 

Chloro-2,2,3-trifluoropropionic acid has been prepared by permanganate oxidation of 3-chloro-2,2,3-trifluoropropanol which is one of the telomerization products of chlorotrifluoroethylene with methanol. The present procedure is a modification of one reported earlier and is undoubtedly the method of choice for making propionic acids containing 2 fluorine atoms, i.e., 2,2,3,3-tetrafluoropropionic acid, 3,3-dichloro-2,2-difluoropropionic acid, and 3-bromo-2,2,3-trifluoropropionic acid. When preparing 2,2,3,3-tetrafluoropropionic acid from tetrafluoroethylene, it is desirable to use an additional 50 ml. of acetonitrile and externally applied heat to initiate the reaction. 

The tetramerization of suitable monopyrroles is one of the simplest and most effective approaches to prepare porphyrins (see Section 1.1.1.1.). This approach, which is best carried out with a-(hydroxymethyl)- or ot-(aminomethyl)pyrroles, can be designated as a biomimetic synthesis because nature also uses the x-(aminomethyl)pyrrole porphobilinogen to produce uroporphyrinogen III. the key intermediate in the biosynthesis of all kinds of naturally occurring porphyrins, hydroporphyrins and corrins. The only restriction of this tetramerization method is the fact that tnonopyrroles with different -substituents form a mixture of four constitutionally isomeric porphyrins named as porphyrins I, II, III, and IV. In the porphyrin biosynthesis starting from porphobilinogen, which has an acetic acid and a propionic acid side chain in the y6-positions, this tetramerization is enzymatically controlled so that only the type III constitutional isomer is formed. 

Papageorgiou and Benezra204 treated chiral r-butyl (-)-(S)- and ( + )-(R)-2-(p-tolylsulfinyl)propionate with an aldehyde, then pyrolyzed the mixture and obtained chiral a-(hydroxyalkyl)acrylate in 75% e.e. Similarly, condensation of the anion of ( + )-(R)-3-(p-tolylsulfinyl)propionic acid 159 with aldehydes was found to give the diastereomeric [i-sulfinyl-y-lactones, (+)-(Sc4,Rc5,Ps)-160a and ( + )-( c4,Sc5,l s)-160b in an approximate ratio of 60 40205. 

C25H27CIO3 /O/Oy-i -J) see Trenbolone acetate ( )-2-chioro-3-[4-[(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)incthoxy]phenyl]propionic acid (C23H27C10 97322-69-5) sec Troglitazone 4 -chloro-2 (24midazoUn-2-yl)benzophenone (Ci HjiClNjO 22590-J7-6) see Mazindo ... 

Naidook S. Separation of Acetic and Propionic Acid Analogs of I Thyroxine and l ltiiodotKynHiine by Thin-Layer Ctoomatography , AnaL Biochem. 1978,91, 543-547. 

Purification of 2-(4 -[ I]iodo-biphenyl-4-sulfonylamino)-3-(l//-indol-3-yl)-propionic acid and 2-(4 -[ I]iodo-biphenyl-4-sulfonylamino)-3-(lff-indol-3-yl)-propionamide... 

H. Ihre, A. Hult, J. M. J. Frechet, and I. Gitsov, Double-stage convergent approach for the synthesis of functionalized dendritic aliphatic polyesters based on 2,2-bis(hydroxymethyl)propionic acid, Macromolecules, 31 (1998) 4061 1068. 

Reaction of acetic acid solutions of Ru3(CO)i2 with mixtures of CO and R2 under pressure produces substantial amounts of methyl acetate and smaller quantities of ethylene glycol diacetate/ as shown in Table I. Other products observed in these reactions are traces of glycerine triacetate and small amounts of ethyl acetate. (The ethanol is apparently derived largely from acetic acid by catalytic hydrogenation, since reactions in propionic acid solvent yield similar quantities of propyl propionate and only traces of ethyl propionate.)... 

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