Hydronephrosis 46

Suprapubic pain and cramping, urinary urgency and frequency, dysuria and burning, hematuria Urinary retention leading to hydronephrosis and renal failure may occur if large blood clots obstruct the ureters or bladder outlet. 

Hydronephrosis Distention of the pelvis and kidney with urine resulting from obstruction of the ureter. 

CAU gross abnormalities were nanoids one high-dose fetus also had exencephaly, shortened mandible, and agenesis of the tail. dAnophthalmia and/or severe microophthalmia. eOne fetus had hydronephrosis. 

Whether or not the kidneys are sliced transversely to examine the renal pelvis varies among laboratories. Hydronephrosis, delayed papillary development, and distended renal pelvis are most readily detected in this manner. However, it is not necessary to slice the kidneys to detect the urinary retention that can lead to distended renal pelvis and hydronephrosis. This point was demonstrated in a study in which 200,000 IU kg 1 day-1 of vitamin A administered orally on Days 8 to 10 of... 

When administered into the newly developed chicken embryo, 6-methyluracil was found to possess strong teratogenic activity. The compound produces abnormalities in 85 per cent of the embryos at 4 mg/kg [270]. In pregnant rats this pyrimidine causes damage to 10-day-old embiyos. Microanatomical examination reveals urogenital system abnormalities (e.g. hydronephrosis, uretal oedema) [271]. 

Administered by injection or inhalation during gestation nickel carbonyl caused fetal mortality, reduced pup weights, and fetal malformations including anophthalmia, microphthalmia, cystic lungs, and hydronephrosis in rats and hamsters. ... 

Gil - Dysuria, oliguria, renal tubular necrosis (5% or more) hydronephrosis, renal damage, renal insufficiency, urinary retention, urinary tract bleeding, urinary tract disorder (2% to less than 5%). 

Urologists may also have selected other patients to receive radiotherapy, namely, those with known poor prognostic factors, including those with hydronephrosis at presentation, higher grade tumors, the presence of anemia, and patients with multifocal tumors. 

On the basis of susceptibility tests of the isolate cultured from the initial urine (or blood), therapy should be streamlined, preferably within 48 hours. In an uncomplicated course a switch to oral therapy should be made after a few days. If defervescence takes longer than a few days repeated physical examination and radiological examination should be performed to exclude hydronephrosis, urinary stones or perinephric abscess. 

Comments/notes/any other findings Hydronephrosis, hydrocephaly same fetuses... 

Mechanism of Action A hormone that influences proliferative endometrium and transforms into secretory endometrium. Secretion of pituitary gonadotropins is inhibited which prevents follicular maturation and ovulation, TircrapeuticEffect Facilitates ureteral dilatation associated with hydronephrosis of pregnancy. 

About 26% of the inhaled nickel was excreted in urine within 4 days absorption estimated at 50% Increased fetal mortality reduced body weight in live pups 16% incidence of fetal malformations (anophthalmia, microphthalmia, cystic lungs, hydronephrosis)... 

Dose-dependent increase in incidence of malformed fetuses — especially cleft palate and hydronephrosis — at 4 mg/kg BW daily and higher. At 16 mg/kg BW and higher, dams had dose-dependent increase in weight loss, frequency ot vaginal bleeding, and other evidence of abortion... 

Dietary administration of 50 mg/kg/day FireMaster BP-6 to mice from gestation days 7 through 18 produced decreased fetal body weight and fetal abnormalities including exencephaly, cleft palate, and hydronephrosis 5 mg/kg/day did not produce significant developmental effects in this study (Corbett et al. 

Hydronephrosis—fluid-filled kidney, often grossly enlarged may be accompanied by a hydroureter (enlarged, fluid-filled ureter)... 

Rat (Han/Wistar) Gd 8 1 x/d (GO) 1 10 (hydronephrosis, thymic atrophy, gastrointestinal hemorrhage, decreased number of live fetuses) Huuskonen et al. 1994... 

The above data suggest that the observed renal effects in mature animals may be secondary to the general response to 2,3,7,8-TCDD toxicity with the exception of the epithelial hyperplasia reported in monkeys. However, developmental studies clearly show that the ureteral epithelium is altered by in utero exposure to CDDs as manifested by hyperplasia of ureteral lining epithelial cells leading to hydronephrosis (see Section 2.2.2.6). 

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