Hydrogen continued isopropyl

Methylenedioxyphenylisopropanolamine is reacted with chloroacetylcatechol in a 3 1 mol ratio in 60% ethanol at reflux temperature with continuous stirring. Stirring and re-fluising were continued for another five hours after which the reaction mixture was cooled and then acidified with 20 cc of concentrated aqueous HCI. The acid solution was concentrated in vacuo to a viscous consistency and the residue dissolved in acetone. On standing, the aminoketone precipitated and was filtered. The precipitate was dissolved in isopropyl alcohol and permitted to recrystallize. An alcoholic solution of this aminoketone precipitate was reduced with PtOj and hydrogen, clarified by filtration, concentrated to dryness in vacuo and the residue crystallized from acetone giving the desired product. 

A pelleted catalyst sample containing 0.32 g. of copper in 10 g. of catalyst was placed in the reaction chamber. The catalyst was reduced in hydrogen at 400° for 2 hours. The temperature was then lowered and held at 225°. Redistilled isopropyl alcohol was fed over the catalyst at the rate of 32 cc. (liquid) per hour. Tests were continued for 1 hour, and three successive such 1-hour activity runs were made for each catalyst. 

Aroylhydroxamoyl chlorides. General procedure ( ). To 0.025 moles of the acetophenone derivative in 100 ml of anhydrous diethyl ether, dry hydrogen chloride and a solution of 0.0375 moles of isopropyl nitrite in 40 ml of anhydrous diethyl ether is added simultaneously over a period of 30 min at 10-20°C. After addition of hydrogen chloride for an additional 2 hours, the solvent is removed by evaporation, and the residue is dissolved again in 100 ml of diethyl ether and an additional amount of 0.025 mole of isopropyl nitrite is added dropwise and simultaneously with hydrogen chloride at 20°C. Addition of hydrogen chloride was continued for approximately two hours, the solvent was evaporated, and the aroylhydroxamoyl chloride was purified by crystallization from benzene or a mixture of benzene and carbon tetrachloride. 

To a stirred suspension of 0.1 mol anhydrous aluminum chloride in 15 mL isopropyl ether was added dropwise at 20-30°C a solution of 0.05 mol phenol and 0.05 mol benzoylacetonitrile in 60 mL isopropyl ether. The mixture, into which dry hydrogen chloride was continuously passed, was gradually heated at 50-60°C and kept for 5 h. The resulting mixture was chilled and poured over water containing crushed ice and concentrated hydrochloric acid. After it was stirred for 0.5 h, filtration and drying gave the crude intermediate shown. (Substitution of isopropyl ether for an inert solvent such as sym-tetrachloroethane afforded a lower yield of such intermediate.) The formation of such intermediate can also be carried out without any solvent but at a higher temperature (e.g., 70-80°C). 

A patent [60] states that batch polymerizations of 7V-vinylpyrrolidone in aqueous solution with hydrogen peroxide often give rise to gel formation. This difficulty can be overcome by replacing at least part of the water with such substances as isopropyl alcohol, thioglycolic acid, dimethylformamide, ethanolamine, methyl ethyl ketone, trichloroacetic acid or 2-mercaptoethanol. A continuous polymerization procedure is said to be particularly effective. Procedure 3-9 is given here only as an illustration of this patented process. 

As mentioned already, alcohols are compounds that have a hydroxyl group (-OH) attached to a carbon atom. The most common alcohols are alkanes that have an oxygen atom inserted between one of the carbon atoms and a hydrogen atom. There are thousands, if not milUons, of alcohols. However, the alcohols people encounter most frequently are methanol, or methyl alcohol (CH3OH) ethanol, or ethyl alcohol (CHjCHjOH) and isopropyl alcohol (CjH OH). In fact, most people just use the word alcohol for any alcoholic beverage instead of the correct name, ethyl alcohol, but everyone knows what they mean. By the way, be sure to note the continued use of the prefixes meth, or methyl, for one carbon eth, or ethyl, for two carbons and prop, or propyl, for three carbons. 

It is clear that the highest concentrations of the propylene and hydrogen chloride can be obtained under conditions where the reaction product (isopropyl chloride) is discharged continuously from the system as it forms. However, it is impossible to remove the isopropyl chloride continuously under the conditions in which the reaction takes place. To do this the reaction mixture would have to be separated in a separate installation (or system of installations), and the components of the raw niaterial then returned to the reaction. In such a system, removal of the reaction product as it forms, resembles operation with an infinitely large recycling coefficient. 

Hospitals, which are typical end users for this equipment, use potent germicides such as Virex , Cidex , Sanicloth and Betadine solutions to disinfect them regularly. Increased sophistication in healthcare has resulted in introduction of a variety of portable medical devices for personalized medicine at individual households. These devices are usually disinfected by household cleaning chemicals like Isopropyl alcohol (IPA), Bleach and Hydrogen Peroxide. Housings made of available commercial grades of FR PC/ABS blends have been known to crack with continued use of these chemicals. 

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