Oxygen atom insertion

Strong oxidizing agents such as m-chloroperbenzoic (MCPBA) acid also react with polysilanes, to insert oxygen atoms between the silicons (17)... 

Numerous bacterial and fungal genera have species able lo degrade hydrocarbons aerobically and the pathways of degradation of representative aliphatic, naphthenic and aromatic, molecules have, been well characterized in at least some species. It is a truism that the hallmark of an oil-degrading organism is its ability to insert oxygen atoms into the hydrocarbon, and... 

Polysilanes are chemically inert to air and water at ordinary temperature, but their reactivity increases in solvent. In a solvent such as tetrahydrofuran, degradation of the Si—Si backbone by strong bases is quite rapid. Strong oxidizing agents like /77-chloroperbenzoic acid insert oxygen atoms between the silicons to produce Si—O—Si linkages in the backbone (120). 

Nature has always been a source of inspiration for scientists. While most of research developments are centered on simulating nature, it would be worthwhile to challenge nature s ingenuity to mimic the synthetic reactions. To this end, catalytic C—H bond amination is an excellent platform for the development of a non-natural enzymatic reaction. Whereas enzymes are capable of inserting oxygen atoms into even inactivated C—H bonds, the sites into... 

The product (6 hexanohde) is a cyclic ester or lactone (Section 19 15) Like the Baeyer-Vilhger oxidation an oxygen atom is inserted between the carbonyl group and a carbon attached to it But peroxy acids are not involved m any way the oxidation of cyclohexanone is catalyzed by an enzyme called cyclohexanone monooxygenase with the aid of certain coenzymes... 

It has been thought that when an oxygen atom is inserted between the phenyl group and the furanone moiety, the activity may be enhanced. A series of alkoxy-lactones 101 were synthesized according to the procedure described by Scheme 30 (99BMC2207). Alcohols are condensed with sodium chloracetate to provide the... 

Note from Figure 21.7 (p. 566) that in both oxides, as in P4 itself, the four phosphorus atoms are at the corners of a tetrahedron. The P406 molecule can be visualized as derived from P4 by inserting an oxygen atom between each pair of phosphorus atoms. In P4O10, an extra oxygen atom is bonded to each phosphorus. 

The overall hydroxylation or epoxidation reaction catalyzed by cytochrome P450s involves the insertion of one oxygen atom, derived from molecular oxygen, into a C-H bond or into the Jt-system of an olefin, with the concomitant reduction of the... 

To summarize, squalene epoxidase is a flavoprotein capable of catalyzing the insertion of oxygen into the 2,3-double bond of squalene to give 2,3-oxidosqualene, with the second oxygen atom from 02 being reduced to water. The reducing equivalents necessary for this transformation are relayed from NADPH through NADPH-cytochrome c reductase to the flavin cofactor of the epoxidase. 

Zollinger and coworkers (Nakazumi et al., 1983) therefore supposed that the diazonium ion and the crown ether are in a rapid equilibrium with two complexes as in Scheme 11-2. One of these is the charge-transfer complex (CT), whose stability is based on the interaction between the acceptor (ArNj) and donor components (Crown). The acceptor center of the diazonium ion is either the (3-nitrogen atom or the combined 7r-electron system of the aryl part and the diazonio group, while the donor centers are one or more of the ether oxygen atoms. The other partner in the equilibrium is the insertion complex (IC), as shown in structure 11.5. Scheme 11-2 is intended to leave the question open as to whether the CT and IC complexes are formed competitively or consecutively from the components. ... 

Phosphorus(V) oxide, P4 Oio, contains the same triangular arrangement of phosphorus atoms as in P4, but an oxygen atom is inserted into each P—P bond. An additional terminal O atom is double-bonded to each P atom. 

The partial oxidation of propylene occurs via a similar mechanism, although the surface structure of the bismuth-molybdenum oxide is much more complicated than in Fig. 9.17. As Fig. 9.18 shows, crystallographically different oxygen atoms play different roles. Bridging O atoms between Bi and Mo are believed to be responsible for C-H activation and H abstraction from the methyl group, after which the propylene adsorbs in the form of an allyl group (H2C=CH-CH2). This is most likely the rate-determining step of the mechanism. Terminal O atoms bound to Mo are considered to be those that insert in the hydrocarbon. Sites located on bismuth activate and dissociate the O2 which fills the vacancies left in the coordination of molybdenum after acrolein desorption. 

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