Human umbilical vein endothelial HUVEC

Shi et al. reported on the synthesis and antiangiogenic activities of lino-mide and its analogs (compounds 11-16) [32], Three of the analogs are 3.3-69 times more potent than linomide at inhibiting blood vessel formation in the chicken chorioallantoic membrane (CAM) [41,42] angiogenesis assay. These compounds possessed considerable antiproliferative activities against isolated human umbilical vein endothelial (HUVEC) cells along with with no... 

In another study, neuroblastoma, human cortical neuronal cells, 3T3, and human umbilical vein endothelial (HUVEC) cells were cultured onto two types of mesoporous silicon with average pore... 

Human umbilical vein endothelial cells (HUVEC) express the isoforms ECE-la, -lb, -Id and ECE-2. In these cells, ET-1 is secreted via both a constitutive and a regulated pathway. The ratio of released ET-1 big-ET-1 is 4 1. About 80% of the ET-1 is secreted at the abluminal cell surface of endothelial cells. ECE-isoforms are abundantly expressed on the cell surface of endothelial cells and to a lower level also on vascular smooth muscle cells. In atherosclerotic lesions of vessels, however, ECE expression in smooth muscle cells is upregulated. ECE isoforms expressed in smooth muscle cells contribute significantly to the generation of mature ET in normal and in particular atherosclerotic vessels. 

The adherence and proliferation of human umbilical vein endothelial cells (HUVECs) were evaluated on the fabricated PCLA scaffold. Results showed that the HUVECs were adhered and proliferated well on the small-diameter-fiber fabrics (0.3 and 1.2 mm in diameter), whereas markedly reduced cell adhesion, restricted cell spreading, and no signs of proliferation were observed on the large-diameter-fiber fabric (7 mm in diameter). That may be due to the high-surface-density fibers provide an extremely high surface/volume ratio, which favors cell attachment and proliferation. 

HUVEC Human umbilical vein endothelial cell... 

MDCK (Madin-Darby canine kidney) cells are derived from distal tubules, whereas LLC-PKi are from proximal tubes. b BMEC (brain microvessel endothelial cells) are isolated from capillaries. BPAEC (bovine pulmonary artery endothelial cells), BAEC (bovine aortic endothelial cells), and HUVEC (human umbilical vein endothelial cells) are large vessel endothelia. 

TIRFM was used for time-lapse observations of initial cell adhesion to SAMs with different surface functionalities (Fig. 2). After 10 min of plating a suspension of human umbilical vein endothelial cells (HUVECs), a few bright spots were observed on SAMs with COOH and NH2 functionalities this indicated cell adherence. The number of bright spots increased and the spot areas enlarged with incubation time, indicating that HUVECs adhered and spread well on COOH-SAM and NH2-SAM surfaces. Quantitative analysis of the number of adherent cells and cell adhesion areas... 

HUVEC, human umbilical-vein endothelial cells... 

Fig. 12. Inhibition of l25I-lys-plasminogen binding to human umbilical vein endothelial cells (HUVECs) by Lp(a) and apo(a). Confluent HUVEC monolayers were washed, treated with -aminocaproic acid, rewashed and incubated with 125I-lys-plasminogen (4.95 nM, specific activity 415.000cpm-pmo -1), for 30 min at 4°C in the presence of various excess amounts of unlabeled Lys-PLG (A) Lp(a) (0,0) apo(a) (x) LDL ( , ) or Lp(-) (V). [With permission of Hajjar el at. (HI 1).]...

Human umbilical vein endothelial cells (HUVEC), used to exemplify tumor spheroid-based migration on a cell monolayer. 

In a more recent paper [160], Urry et al. reported that x20-poly (GGAP) was nonadhesive to both bovine ligamentum nuchae fibroblast and human umbilical vein endothelial cells (HUVECs), even in the presence of serum. Urry et al. interpreted this behavior in terms of their hydrophobicity scale. They suggested that x20-poly[50(GGAP), (GRGDSP)], for example, could provide the inner lamina for a vascular prosthesis. 

For target selection, adhesion molecules are expressed on the surface of endothelial cells. For this purpose, sialyl Lewis X is used as the guide molecule in the case of expression of P- and E-selectins for TNFa-activated HUVEC (human umbilical vein endothelial cells). Thus, targeting membrane-bound antigens in situ is also possible with this technique. 

Figure 6.2 Immunocytochemical detection of catechol-O-methyl transferase (COMT) in human umbilical vein endothelial cells (HUVEC). Polyclonal COMT antibody from Chemicon Millipore, USA. (From Kravets E. [2008].)...

HSMCs) and human umbilical vein endothelial cells (HUVECs) were microinjected in the nucleus (top) and cytoplasm with CMV-driven, GFP-expressing plasmids containing either... 

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