Human microvascular endothelial cell

HMW High molecular weight HMT Histidine methyltransferase HMVEC Human microvascular endothelial cell... 

Salcedo R, Resau JH, Halverson D, et al. Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells. FASEB J 2000 14(13) 2055-2064. 

Haraldsen, G., Kvale, D., Lien, B., Farstad, I.N. and Brandtzaeg, P. (1996) Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (IGAM-1), and vascular cell adhesion molecule-1 (VGAM-1) in human microvascular endothelial cells. Journal of Immunology 156, 2558-2565. 

A. R. Gagliardi, M. F. Taylor, and D. C. Colhns. Uptake of suramin by human microvascular endothelial cells. Cancer Lett. 125 97-102 (1998). 

Gupta, K., Kshirsagar, S., Li, W., Gui, L., Ramakrishnan, S., Gupta, P. etal. (1999) VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp. Cell Res., 247, 495-504. 

Eue I, Sorg C. 2001. Arachidonic acid specifically regulates binding of S100A8/9, a heterodimer complex of the S100 class of calcium binding proteins, to human microvascular endothelial cells. Atherosclerosis 154(2) 505—508. 

R. Hamanaka, K. Kohno, T. Seguchi, K. Okamura, A. Morimoto, M. Ono, J. Ogata and M. Kuwano, Induction of low density lipoprotein receptor and a transcription factor SP-1 by tumor necrosis factor in human microvascular endothelial cells, J. Biol. Chem. 267 (1992) 13160-13165. 

S. M. Sagnella, F. Kligman, E. H. Anderson, J. E. King, G. Murugesan, R. E. Marchant, and K. Kottke-Marchant, Human microvascular endothelial cell growth and migration on biomi-metic surfactant polymers, Biomaterials, 25 (2004) 1249-1259. 

Scott NA, Candal FJ, Robinson KA, et al. Seeding of intracoronary stents with immortalized human microvascular endothelial cells. Am Heart J 1995 129 860-866. 

Bovine capillary endothelial cells, human microvascular endothelial cells [tCP of alkanthiols on gold surface, protein backfill 1997, 1998 [99, 101]... 

McCramick CJ, Craig A, Roberts D, Newbold Cl, Berendt AR Intercellular adhesion molecule-1 and CD36 syner e to mediate adherence of Plasmodium folciparum-infected erythrocytes to cultured human microvascular endothelial cells. J Clin Invest 100 2521-2529,1997... 

Marks, R.M., Roche, W.R., Czemiecki, M., Penny, R, and Nelson, D.S. (1986). Mast cell granules cause proliferation of human microvascular endothelial cells. Lab. Invest. 55, 289-294. 

In addition, tuna triacylglycerol had no effect on the Matrigel-induced capillary-like network formation by human microvascular endothelial cells (HMVECs), while free DHA significantly inhibited Matrigel-induced capillary-like networks at 1 to 1000 pM Fig. (7) . Oleic acid inhibited the capillary-like formations at 10 to 1000 pM Fig. (7) . 

A recent study has provided insight into the association of ambient air pollution with increased cardiovascular morbidity and mortality. In this study, when human microvascular endothelial cells were exposed to a combination of ultrafine diesel exhaust particles and oxidized lipid components, a synergistic effect on the expression profiles of several gene modules that correspond to pathways relevant to inflammatory pathways such as atherosclerosis was observedJ57l The implications of this study include a greatly increased risk of heart disease in those with high cholesterol who breathe polluted air. 

Cemazar, M., Parkins, C.S., Holder, A.L., Chaphn, D.J., Tozer, G.M., and Sersa, G. (2001) Electroporation of human microvascular endothelial cells evidence for an anti-vascular mechanism of electrochemoflierapy. British Journal of Cancer, 84, 565-570. 

Hermanns MI, Unger RE, Kehe K, et al. Lung epithelial cell lines in coculture with human microvascular endothelial cells development of an alveolo-capillary barrier in vitro. Lab Invest 2004 84 736-752. 

Schutyser E., Su Y., Yu Y., et al. (2007) Hypoxia enhances CXCR4 expression in human microvascular endothelial cells and human melanoma cells. Eur Cytokine Netw. 18, 59-70. 

Siano, J. P., Grady, K. K., Millet, P., and Wick, T. M. (1998). Short report Plasmodium falciparum Cytoadherence to alpha(v)beta3 on human microvascular endothelial cells. Am. ]. Trap. Med. Hyg. 59, 77-79. 

Salcedo R, Zhang X, Young HA, Michael N, Wasserman K, Ma WH, Martins-Green M, Murphy WJ, Oppenheim JJ. Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood. 102 (2003) 1966-1977. 

Fig. (7). Effects of DHA on Matrigcl-induced capillary-like network formation by human microvascular endothelial cells (HMVEC) in vitro). A) Light micrographs showing capillary-like network formation by HMVKC in the presence of various concentrations of DHA (x 100 magnification). R) Inhibition of capillary-like network formation by IIMVEC in the presence of various concentration of DI1A. Values are means a- SE of 4 experiments. Significantly different from medium alone, F<0.05.

Fig. (9). Effects of EPA ethylestcr, EPA derivatives (KRAI)), E-l and E-2 on H-thymidine incorporation into the BN A of L1.C cells (a) or human microvascular endothelial cells (IIMVEC) (b). Values are means + SE of 4 experiments. Significantly different front medium alone, P<0.l)5 significantly different from EPAethylester at0.33, 3.3 and 33 pg ml, P<0.05.

Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J. Cell. Physiol. 157 351-358. 

T. Shono, M. Ono, H. Izumi, S. Jimi, K. Matsushima, T. Okamoto, K. Kohno, M. Kuwano (1996). Involvement of the transcription factor NF-/cB in tubular morphogenesis of human microvascular endothelial cells by oxidative stress. Mol. Cell. Biol, 16, 4231 239. 

C.A. Bootle-Wilbraham, S. Tazzyman, W.D. Thompson, C.M. Stirk, C.E. Ixwis, Fibrin fragment E stimulates the proliferation, migration and differentiation of human microvascular endothelial cells in vitro. Angiogenesis 4 (2001) 269-275. 

Fig. 8 Schematic of tumor-vessel co-culture devices and fluorescent images showing the invasion process of Brain cancer cells (U87MG). The cancer cells invaded into the collagen type I gel and was approaching the human microvascular endothelial cells (HMVEC).[76]...

Rod-like, semiflexible, and ring-shaped polymers were claimed to be promising candidates as drug delivery vehicles, showing prolonged in vivo circulation times [70-73] and excellent accumulation in tumor cells [72, 74]. Reports on complexes of stiff polycations with DNA are rare. Besides other reports [75, 76], puUulan modified with spermine groups was reported to transfect T24 cells of a human bladder cancer cell line [77], HepG2 cells of a human hepatoma cell line [78, 79], and human microvascular endothelial cells [80]. 

Human Microvascular Endothelial Cells (HMVEC) (1x10 /ml)... 

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