Hodgkin lymphoma types

These investigations have shown significant associations with several types of cancer, but the most consistent findings have been for soft-tissue sarcoma and non-Hodgkin lymphoma. Although the odds ratios in some case-control studies may have been inflated by recall bias, this cannot explain all of the findings. Nor are they likely to have arisen by chance. It is not possible, however, to exclude a confounding effect of polychlorinated dibenzo-para-dioxins which occur as contaminants in chlorophenols. 

Xylene was mentioned as an exposure in four studies. Two were community-based case-control studies, one of which involved brain cancer and one involved several types of cancer. The two industry-based studies were configured as nested case-control studies, one of central nervous system tumours and one of several sites. In none of these studies was xylene the sole or predominant exposure. Cancers at most sites were not significantly associated with xylene exposure in any study. Incidence of colorectal cancer was significantly elevated in the Canadian case-control study, but no other study reported colorectal cancer results. Hodgkin s disease was elevated in one study non-Hodgkin lymphoma was elevated in one study, but not in another. Most results were based on small numbers. In... 

The liver is the most frequently affected non-lymphatic organ in Hodgkin lymphoma (30-50% of cases). Liver involvement is highest in the lymphocytopenic type... 

Interferon alfa-2b Intron A (Schering-Plough) Hairy cell leukemia AIDS-related Kaposi s sarcoma chronic hepatitis, types B and C condylomata acuminata malignant melanoma follicular lymphoma non-Hodgkins lymphoma... 

Hodgkin lymphoma (HL) is widely accepted to be a malignant clonal proliferation of B lymphocytes or, less often, T lymphocytes surrounded by variable numbers of inflammatory cells and fibrosis. The two major histologic types are classical Hodgkin lymphoma (CHL) and nodular lymphocyte predominance Hodgkin lymphoma (NLPHL). Classical Hodgkin lymphoma is further subdivided into four subtypes ... 

CD74 functions as an MHC class II chaperone and is normally expressed by a variety of cell types including B cells, activated T cells, macrophages, activated endothelial cells, and epithelial cells. Although expressed by the H/RSCs of CHL, CD74 is not specific for this lymphoma expression has been reported in a variety of non-Hodgkin lymphomas as well as in non-lymphoid epithelial malignancies. 

Type Lymphoma Hodgkin Lymphoma Lymphoma Lymphoma Lymphoma... 

The immunoprofile of MNHL separates it from other malignant mixed-cell neoplasms of the mediastinum. It includes reactivity for CD45 in all lesional cells, as well as positivity for CD20 in B-cell tumors or CD3, CD43, or CD45R0 in T-cell neoplasms.Keratin is universally absent, but some p63 isoforms are variably expressed by non-Hodgkin lymphomas of various types. 

Recently few interesting observations show that clonality analyses may be also useful to analyze some types of classical Hodgkin s lymphoma, namely nodular sclerosis and lymphocyte predominance type, as the vast majority of the neoplastic L H cells (about 95%) proved to be of B-cell origin, i.e. from germinal center B-lymphocytes. The rest ( 5%) of L H cells seems to be of T- or null-cell origin. The IgH rearrangement is found in up to 20% of Hodgkin s lymphoma types. 

Post-transplant B-cell disorders include lymphoid hyperplasia, PTLD, and malignant lymphoma (mostly non-Hodgkin in type) (Figs. 2.2.10, 2.2.11). They occur in 2%-6% of cardiac transplant recipients and PTLD is associated with Epstein-Barr virus infection and immunosuppression (Armitage et al. 1991 Higgins et al. 2003 Knisely et al. 1999 ... 

Lymphoma types Hodgkin s (14), non-Hodgkin s (20), follicular (lO), mantle cell (5), B-cell (4), small lymphocytic (l) excluded Burkitt s and CNS lymphoma. 

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