Hazard identification report

This module is divided into two sections. First one is related to hazard analysis and uses HAZOP methodology. It gives the possibility to make hazard identification reports as well as storing external sources used in the analysis, e.g. P ID (piping installation diagrams), documentation, etc. 

Lucic, 2003b) ATKINS RAIL REPORT- Lucic I. (2003) Axle Counter Modelling Enhancements, High Level Hazard Identification Report (Reference 1956710-L-HA-001, version 00.04, dated 09-01-2003). London. 

The project constructor shall develop a project hazard identification report. The report shall include, at a... 

The project constructor s project hazard identification report. 

Each contractor shall review the project constructor s project hazard identification report. Potentially hazardous tasks identified by a contractor that are not addressed in the report shall be reported by that contractor to the project constructor. 

Generate a project hazard identification report to share with all contractors and other affected project personnel by listing the tasks that meet the criteria established in the preceding two major bullets above. Provide a detailed, written description of each of them including the anticipated hazards. 

Figure 7.2 Sample written statement on hazard identification reporting.

In this study detailed fault trees with probability and failure rate calculations were generated for the events (1) Fatality due to Explosion, Fire, Toxic Release or Asphyxiation at the Process Development Unit (PDU) Coal Gasification Process and (2) Loss of Availability of the PDU. The fault trees for the PDU were synthesized by Design Sciences, Inc., and then subjected to multiple reviews by Combustion Engineering. The steps involved in hazard identification and evaluation, fault tree generation, probability assessment, and design alteration are presented in the main body of this report. The fault trees, cut sets, failure rate data and unavailability calculations are included as attachments to this report. Although both safety and reliability trees have been constructed for the PDU, the verification and analysis of these trees were not completed as a result of the curtailment of the demonstration plant project. Certain items not completed for the PDU risk and reliability assessment are listed. 

FIGURE 7.1.3 Process of hazard identification, Source SSC, First report on the harmonisation of risk assessment procedures, Part 1, October 2000. )... 

There are significant differences in the laws authorizing the OSHA PSM Standard and the EPA RMP regulation. Because EPA specifically lists substances covered under RMP and does not establish classes of substances, this report separately discusses alternatives for OSHA (Section 8.1) and EPA (Section 8.2). (Section 8.3 briefly discusses regulatory relief absent catastrophic consequences, and Section 8.4 suggests improvements within the requirements of the existing PSM Standard and RMP regulation to enhance hazard identification and hazard evaluation.)... 

As mentioned previously, there are no test guideline methods for respiratory irritation. Good data, often clearly related to exposure levels, can be obtained on respiratory and mucous membrane irritation, from well-designed and well-reported inhalation studies in animals. Also the Alarie test (Alarie 1973, 1981), an experimental animal test assessing the concentration that results in a 50% reduction of the breathing frequency, may provide useful information on sensory irritation of the upper respiratory tract and the results may be used for hazard identification. 

Rovida, C. and van de Sandt, J. (2007) Skin sensitisation and epidermal disposition the relevance of epidermal disposition for sensitisation hazard identification and risk assessment. The report and recommendations of ECVAM workshop 59. Alternatives to Laboratory Animals, 35, 137-154. 

J.P., Meade, B.J., Pallardy, M., Rougier, N., Rousset, F., Rubinstenn, G., Sallusto, F., Verheyen, G.R. and Zuang, V. (2005) Dendritic cells as a tool for the predictive identification of skin sensitisation hazard. The Report and Recommendations of ECVAM Workshop 51. Alternatives to Laboratory Animals, 33, 47-62. 

In the chemical safety report, the hazard assessment of a particular substance is based on the data set provided in the technical dossier. This contains substance-specific information on physicochemical properties as well as on toxicological and ecotoxicological hazards. One objective of the hazard assessment is the substance s hazard identification, which comprises the determination of its physicochemical and hazardous properties for the purpose of classification. Concerning human health hazards, both human and nonhuman information is taken into consideration and evaluated with respect to the classification criteria laid down in the Dangerous Substances Directive and in the CLP Regulation, respectively. However, in most cases human data do not exist, so the hazard identification has to be based on data from animal experiments. With respect to teratogenicity, this hazardous property may in principle be detected in the following toxicity studies ... 

Although dose-response assessments for deterministic and stochastic effects are discussed separately in this Report, it should be appreciated that many of the concepts discussed in Section 3.2.1.2 for substances that cause deterministic effects apply to substances that cause stochastic effects as well. The processes of hazard identification, including identification of the critical response, and development of data on dose-response based on studies in humans or animals are common to both types of substances. Based on the dose-response data, a NOAEL or a LOAEL can be established based on the limited ability of any study to detect statistically significant increases in responses in exposed populations compared with controls, even though the dose-response relationship is assumed not to have a threshold. Because of the assumed form of the dose-response relationship, however, NOAEL or LOAEL is not normally used as a point of departure to establish safe levels of exposure to substances causing stochastic effects. This is in contrast to the common practice for substances causing deterministic effects of establishing safe levels of exposure, such as RfDs, based on NOAEL or LOAEL (or the benchmark dose) and the use of safety and uncertainty factors. 

Hazard Identification. The first step is to determine whether a substance is mutagenic. For this purpose, inexpensive and sensitive short-term tests have been developed and are extensively used, nils report discusses the general features of these tests and proposes a specific mutagenicity screening program to detect potential mammalian mutagens. 

Jim Skeaff and Pierrette King, Development of Data on the Reaction Kinetics of Nickel Metal and Nickel Oxide in Aqueous Media for Hazard Identification, Final Report, January 1998. Mining and Mineral Sciences Laboratories Division Report 97-089(CR)/Contract No. 51605... 

In 1983, the National Research Council of the (US) National Academy of Sciences published a report titled Risk Assessment in the Federal Government Managing the Process this work has had a marked influence on the risk assessment process used by regulatory agencies worldwide. The risk assessment process, in this report, consists of four components hazard identification, dose-response assessment, exposure assessment, and risk characterization. 

Hazard identification in the context of the report is concerned with evaluating the potential adverse health effects of a chemical, mixture of chemicals, or process thus, it is very similar to the traditional term toxicity used by toxicologists. 

Several animal models have been developed to study mechanisms of respiratory allergic responses to proteins and chemicals. However, only a few of these have been used as predictive tests in hazard identification and risk assessment. These models have employed guinea pigs, mice or rats. This report describes guinea pig models developed as predictive tests for risk assessment of proteins and LMW chemicals as respiratory allergens. 

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