Gastrointestinal problem

COX-2 selective drugs comprise an alternative strategy for reducing the risk of gastric irritation. As indicated earlier, the COX-1 enzyme is responsible for synthesizing prostaglandins that help protect the 

---

The daily dose of allopurinol is 300-600 mg. In combination with benzbromarone, the daily allopurinol dose is reduced to 100 mg. In general, allopurinol is well tolerated. The incidence of side effects is 2-3%. Exanthems, pruritus, gastrointestinal problems, and dty mouth have been observed. In rare cases, hair loss, fever, leukopenia, toxic epidermolysis (Lyell syndrome), and hqDatic dysfunction have been reported. Allopurinol inhibits the metabolic inactivation of the cytostatic dtugs azathioprine and 6-mercaptopurine. Accordingly, the administered doses of azathioprine and 6-mercaptopurine must be reduced if allopurinol is given simultaneously. 

The daily dose of benzbromarone is 50-200 mg. In combination with allopurinol, the benzbromarone dose is reduced to 20 mg. Benzbromarone is well tolerated. Rare side effects are headaches, gastrointestinal problems, and exanthems. 

Antithyroid drags have several side effects. The most frequent side effects are maculopapular rashes, pruritus, urticaria, fever, arthralgia and swelling of the joints. They occur in 1-5% of patients [1, 2]. Loss of scalp hair, gastrointestinal problems, elevations of bone isoenzyme of alkaline phosphatase and abnormalities of taste and smell are less common. The incidence of all these untoward reactions is similar with MMI and PTU. Side effects of MMI are dose-related, whereas those of PTU are less clearly related to dose [1]. PTU may cause slight transient increases of serum aminotransferase and y-glutamyl transpeptidase concentrations but also severe hq atotoxicity whereas methimazole or carbimazole can be associated with cholestasis. The side... 

In patients having Parkinson s disease, both entacapone and tolcapone potentiate the therapeutic effect of L-dopa and prolong the daily ON time by 1-2 h. In the clinic, COMT inhibitors have been well tolerated, and the number of premature terminations has been low. In general, the incidence of adverse events has been higher in tolcapone-treated patients than in entacapone-treated patients. The main events have comprised of dopaminergic and gastrointestinal problems [2,3]. 

Clarithromycin 500 mg twice daily or 1 g once daily (XL only) 1 5 mg/kg per day in 2 doses XL tablets reported to have fewer gastrointestinal problems and taste disturbances than twice-daily preparation... 

Doxycycline 100 mg twice daily Avoid in children under 8 years Can cause photosensitivity, gastrointestinal problems, tooth staining in young children many drug-drug interactions (antacids, iron, calcium)... 

Looking back on it, I was a classic case. Chronic bladder infections, panic attacks, gastrointestinal problems, brain fog, weakness, skin rashes. I was a mass of panic and fatigue. I went to every olo-gist and specialist that there was. None of them was taking a holistic approach. I don t remember any of them ever doing any kind of occupational or environmental assessment, and it never occurred to me. I was just as puzzled as puzzled could be. I m embarrassed to say it took me fifteen years to find the cause. 

There is a disease known as beriberi that causes weakness, fatigue, psychosis, gastrointestinal problems, peripheral nerve damage, brain damage, and ultimately death. Many years ago, this disease was particularly prevalent in rice-eating Asian societies that polished their rice. The polishings contain an essential human nutrient... 

Very large doses of vitamins can be harmful an excess of vitamin A can cause foetal malformations and can be fatal (a risk which is reduced if the vitamin is taken in the form of P-carotene) massive amounts of vitamin C can cause gastrointestinal problems. 

Adverse reactions to carbamazepine include nystagmus, ataxia, diplopia, particularly if the dosage is raised too fast. Gastrointestinal problems and skin rashes are frequent It exerts an antidiuretic effect (sensitization of collecting ducts to vasopressin water intoxication). 

N.A. Limonene, terpineol, linalool, tannins, flavonoids, terpenes." For gastrointestinal problems such as diarrhea and dysentery. Treat bleeding hemorrhoids, bladder problems, gonorrhea. 

Not recommended for patients with renal insufficiencies Should be used with caution in patients with gastrointestinal problems Hypocalcemia should be corrected before initiating therapy Pregnancy Category C... 

Is there any risk in trying this supplement It would appear to be minimal. Although ginkgo may cause such side effects as mild gastrointestinal problems, headaches, and allergic reactions. 

Unfortunately, cancerous cells are not the only cells in the body that divide. Normal cells divide periodically, and some types of cells, such as those in the gastrointestinal tract and in hair follicles, are always in a state of cellular division. As a consequence, cancer chemotherapeutics are noted for their toxicity, with patients undergoing treatments often experiencing gastrointestinal problems and hair loss. 

Pharmacokinetics attd Pharmacology. Older macrolides such as erythromycin exhibit relatively low serum concentrations, short in vivo half-hves, highly variable oral absorption, and low oral bioavailability. Improvements in these pharmacokinetic parameters have been accomplished for newer derivatives. The principal side effects of macrolides aie gastrointestinal problems, such as pain, indigestion, diarrhea, nausea, and vomiting. 

Gastrointestinal effects are common when flutamide is used to treat advanced cases of prostate cancer. At doses of 250 mg every 8 hours or 500 mg/day, 23 of 106 men had gastrointestinal problems, irrespective of the dosage regimen (45). There was no difference in the incidence of these effects in the 56 men who had previously received external beam radiation and 50 others who had undergone radical prostatectomy. This suggests that the gastrointestinal adverse effects of flutamide are not due to a local toxic effect. 

In 120 patients with type 1 diabetes, acarbose lowered postprandial glucose but did not reduce HbAlc (22). Four patients taking acarbose withdrew because of gastrointestinal effects, which improved after withdrawal. One of the placebo group withdrew because of gastrointestinal problems and one other patient taking acarbose withdrew with a Bell s palsy, which was not considered to be related to acarbose. 

---