Alternative Strategies

The synthesis of bicyclic y-lactam-piperazinone derivatives has been reported by Hulme et al. [8b] as an extension of the UDC strategy. Alternatively, the formation of y-lactams by reacting y-keto acids, amines, and isocyanides [89] has been ex-... 

Flint, O.P. In Vitro toxicity testing - purpose, validation and strategy. Altern. LabAnim. 18 11-18, 1990. 

For the process shown in Figure 10.3, what control strategy alternatives may be used to maintain a specified purity for product B if the feed composition changes ... 

Use Top-Down/Bottom- Up Design Strategies Alternately. Approaches [hat scopa ont options in light of ovaraII process design objectives should be used alternately with eppionches that evaluate these objectives at the local level for feasibility. 

Target markets Value proposition Operations activities and processes Value delivery system (customer profiles) // (strategy) // // alternatives /... 

The installation of amino-functional groups, in practice, was most easily accomplished at the C-4 position (Scheme 1.9). For instance, the a-D-pyranone ring on methymycin analog 45 could be converted into a 4-aminosugar 41 with a-o-rhodino-stereochemistry in four steps, via a reduction, activation of the resulting alcohol, azide inversion, and reduction strategy. Alternatively, this approach is... 

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