Garlic bulb Allicin

Allium chinense Max. A. odorum L. A. sativum L. A. tuberosum Roxb. A. uliginosum G. Don Da Suan (Garlic) (bulb) Allicin, allistatin, glucominol, neo-allicin, steroidal saponins, polysaccharides, furostanol saponins, proto-isoerubosides, diallyl sulfide.33 49 438 490-510 Antibacterial, antimutagenic, anticarcinogenesis, carminative, antiarrhythmic, lower plasma cholesterol and low-density lipoproteins, prevent thrombosis, hypotensive and vessel protective effect. 

Garlic supplements - powder tablets or capsules, steam-distilled oil, vegetable oil macerate extract, or extract aged in dilute alcohol - are widely available and are taken by millions. Since the active principle, allicin, is not present in garlic bulb, the supplements rely on the presence of precursor alliin and enzyme alliinase. In tests on 24 commercial brands of enteric-coated tablets, all except one gave low dissolution allicin release 83% of the brands released less than 15% of their potential allicin.78,79 Relevant factors were impaired enzyme activity caused by excipients and slow tablet disintegration. Caveat emptor ... 

Garlic has been a valued commodity throughout history. It has been used in Chinese herbal medicine for more than 4000 years, as a form of currency in Siberia, and as a repellent for witches by the Saxons. Today it is used as a dietary supplement because of its reported health benefits. Allicin, the molecule responsible for garlic s odor, is a rather unstable molecule that is not stored in the garlic bulb, but rather is produced by the action of enzymes when the bulb is crushed or bruised. 

Garlic HP — Physiologies, 400-mg garlic bulb (1000 pg allicin/g yield)... 

Nature s Resource Garlic Cloves, 400-mg capsules garlic bulb (0.8 mg allicin)... 

Early in vivo experiments (1913) showed that garlic and its compounds acted against mmors in mice, with similar results obtained by others (Reuter, Koch, and Lawson, in Garlic, pp. 178-186). Not only could mmor growth be inhibited, but alliin as freshly obtained from garlic bulbs and directly injected into rat sarcomas, resulted in reduction and dissipation. Similar results were obtained for intramuscular injections. Others, however, reported otherwise. On the other hand, allicin deactivated ehrlich ascites mmor cells, and also deactivated cells of Yoshida sarcoma (a mammary tumor). Other examples are described in the reference, with the note that fresh garlic neutralizes cancer cell virulence without compromising the immune response, whereby atumals at least become immune to untreated mmor cells. 

Nature Garlic iAllium sativum) contains organic thiosulfinates that can form allicin (responsible for the characteristic odorj via enzymes that are activated by disruption of the garlic bulb. 

Allium sativum L. Garlic Bulb, oil Hypa cholesterolemia, diabetes, hypertension, respiratory infections Alliins, allicin, ajoens, oligosulfides... 

Allicin (= S-Oxodiallyl Allium sativum (bulb, garlic oil) (Liliaceae) OD-R (garlic) main garlic... 

From crushed Allium cepa, A. sativum (garlic) (Liliaceae) bulbs via allinase from Allicin... 

Garlic HP 650 — Physiologies, bulb powder (allicin yield 6500 pg, total thiosulfinates 6500 pg, alliin yield 14,500 pg, y-glutamylcysteines 5200 pg)... 

The essential oil, which is present in the fresh bulb in a concentration of 0.1 to 0.3%, contains diallyl sulphide, diallyl trisulphide and allyl methyl disulphide (derivatives of allicin) as main components. Apart from further allyl polysulphides, the steam distilled oil contains limonene as non-sulphurous component [111]. The high pungency of garlic oil makes it necessary to dilute it, commonly in vegetable oil. One gram of oil is equivalent to 900 g of fresh garlic or 200 g of dehydrated garlic powder [112]. 

Allicin is one of the major allergens in garlic (Allium sativum L.). It is responsible of the characteristical flavour of the bulbs. 

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