Diallyl sulphide

Oxidation of di-n-butyl sulphide with activated manganese dioxide in light petroleum gave di-n-butyl sulphoxide exclusively126. However, the reaction was very slow at room temperature. This reagent is also suitable for oxidation of diallyl sulphides although, after 76 h, diallyl sulphoxide was isolated in 13% yield only. 

The essential oil, which is present in the fresh bulb in a concentration of 0.1 to 0.3%, contains diallyl sulphide, diallyl trisulphide and allyl methyl disulphide (derivatives of allicin) as main components. Apart from further allyl polysulphides, the steam distilled oil contains limonene as non-sulphurous component [111]. The high pungency of garlic oil makes it necessary to dilute it, commonly in vegetable oil. One gram of oil is equivalent to 900 g of fresh garlic or 200 g of dehydrated garlic powder [112]. 

Leuchs, Lemcke, Ber., 1914, 47, 2584. Diallyl sulphide (Allyl sulphide)... 

Bu Li at - 30 °C, followed by treatment with Mel. A diallyl sulphide behaves similarly in that one of the two S-substituents is lithiated, and this centre is the point at which the y-carbon of the other S-substituent is attached in the product. Compounds (67)—(69) are formed in approximately equal amounts by the photolysis of the /S-alkylthioalkyl-carbene derived from 3-crotyl-3-methylbutyrophenone tosylhydrazone sodium salt. An a-allylthioalkyl-carbene (70) behaves differently on irradiation at - 70 °C, giving an intermediate (71) which rearranges, without the need for irradiation, to give the violet thione (72) this last step is the first... 

Hexamethyldisilthiane convens ketones to thioketones in the presence of Me3SiOTf, gives diallyl sulphides from the alcohol using 130.BF3, peptide thioacids from the Kaiser s oxime ester resin, and2H-l,2-dithiole-3-thiones from ketones and CS2 using NCS. Ph3SiSH... 

Abhaykumar NK, Prasad MPR, Panpatil W, Prasanna Krishna T, Sesikeran B, Polasa K (2011) Reduction in platelet aggregation (in vitro) by diallyl sulphide in female participants with type 2 diabetes mellitus. J Pharmacol Toxicol 6(4) 381-390... 

Kinetics of the oxidation of diallyl sulphide by singlet oxygen, and its inhibition by rubrene, have been reported. Isomerization studies in which the base-catalysed prop-2-eny 1-prop-1-enyl equilibrium for allyl sulphides, sulphoxides, and sulphones were compared have been undertaken, and isolated reports on this topic have been rationalized in terms of electronic distribution in the functional groups. 

Mercurated derivatives of morpholine, tetrahydro-l,4-thiazine, and hexa-hydropyridazine are readily available from diallyl ethers, diallyl sulphides, or... 

Other miscellaneous additions reported include the photoaddition of thiocarboxylic acid to 3,4-diallyl-1,6-propano-1H,6H-3a-thia (S )-1,3,4,6-tetraazapentalene-2,5(3H,4H)-dithione, the Paterno-BUchi addition of methyl vinyl sulphides to benzophen-... 

The formation of a- and 9-allylated sulphides by the Pummerer-type reaction of vinylic sulphoxides with allylmagnesium bromide has been reported by Iwata et al. Monoallylation and diallylation can take place, depending on the bulkiness of the yS-substituent, and both acyclic and cyclic vinyl sulphoxides undergo the reaction. This method offers applicability to asymmetric synthesis using sulfinyl chirality. 

Thermolysis of allyl 2-thienyl sulphide (224) yields a mixture of the thiol (225), the diallyl compound (226), and the bicyclic heterocycles (227) and (228)." In the base-induced Truce-Smiles rearrangement of 5-mesitylenesulphonyl-2-methylthiophen (229) to yield (230), the thienyl group migrates with a change in... 

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