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Focus of responsibilities

A protocol provides a focus of responsibilities for all members of the study team. The combination of a clearly stated objective, along with a clear definition of the methods and materials, will avoid confusion during the study when often there 1s not time for extensive consultation among the study team. [Pg.56]

Indeed, in this nuclear age, a new corporate scenario (Scenario 3) has emerged. This scenario places the focus of responsibility within the team. [Pg.351]

In this scenario, key drug development operations are focused under one banner. Peer groups, with similar report structure and supervisors, administer responsibility for corrective and preventative actions. Indeed, in this age, a new corporate scenario (Scenario 3) has emerged. This scenario places the focus of responsibility within the... [Pg.440]

With these kinds of concerns in mind, the Organization of Economic Cooperation and Development (OECD, 2004) recommends that educational efforts be tailored to the child s stage of development, and that the focus of responsibility for child road safety be shifted more... [Pg.643]

Incident or site-level coordination tends to occur close to the area of impact and focus of response, from what is usually referred to as an incident command post, incident control point, or similar. Incident management at this level is usually populated by low-level managers of the agencies contributing to the response and may include supervisors of field components of critical infrastructure providers. Despite this use of the term incident, the same term is often applied to all levels of emergency and disaster. [Pg.964]

The focus of the present chapter is the application of second-order nonlinear optics to probe surfaces and interfaces. In this section, we outline the phenomenological or macroscopic theory of SHG and SFG at the interface of centrosymmetric media. This situation corresponds, as discussed previously, to one in which the relevant nonlinear response is forbidden in the bulk media, but allowed at the interface. [Pg.1275]

Among vertebrate species, the neuro-endocrine-immime system is responsible for many complex, inter-related physiological processes including neuronal, homeostatic, reproductive and immune functions. There are four main types of hormone polypeptides, eicosanoids, steroids and thyroid hormones. Reflecting the inter-dependency of the neiiro-endocrine and immune systems, hormones, neuropeptides and other neiirotransmitters are known to be produced by some immune cells and play a role in the regulation of the immune system, while endocrine and nervous tissues express receptors for many substances produced by the immune system. The major focus of interest in endocrine disruption has... [Pg.62]

It appears that chromium(III) is an essential trace element in mammalian metabolism and, together with insulin, is responsible for the clearance of glucose from the blood-stream. Tungsten too has been found to have a role in some enzymes converting CO2 into formic acid but, from the point of view of biological activity, the focus of interest in this group is unquestionably on molybdenum. [Pg.1035]

When a temperate phage is mixed with sensitive indicator bacteria and plated as described above, the reaction at each focus of infection is generally a combination of lytic and lysogenic responses. Some bacteria will be lysed and produce phage, others will survive as lysogenic cells, and the plaque becomes visible as a partial area of clearing in the bacterial lawn. It is possible to pick off cells from the central areas of these plaques and demonstrate that they carry prophage. [Pg.60]

Since early in this century the concept of the active site in catalysis [1] has been a focus of attention in this area of chemistry. This was proposed to be that ensemble of surface atoms/reactants which is responsible for the crucial surface reaction step involved in a catalytic conversion. Since those days much work has been done in the area, which cites the concept of the active site. However, no such ensemble has been positively identified due to the lack of availability of techniques which could image such a structure, which is of atomic dimensions. [Pg.287]

Under conditions of copper deficiency, some methanotrophs can express a cytosolic, soluble form of MMO (sMMO) (20-23), the properties of which form the focus of the present review. The sMMO system comprises three separate protein components which have all been purified to homogeneity (24,25). The hydroxylase component, a 251 kD protein, contains two copies each of three subunits in an a 82y2 configuration. The a subunit of the hydroxylase houses the dinuclear iron center (26) responsible for dioxygen activation and for substrate hydroxylation (27). The 38.6 kD reductase contains flavin adenine dinucleotide (FAD) and Fe2S2 cofactors (28), which enable it to relay electrons from reduced nicotinamide adenine dinucleotide (NADH) to the diiron center in the... [Pg.267]

Nowadays most trials of psychotropic drugs are multicentric, and an increasing number of them are carried out in different regions of the world. However, ethnic variations in response to the tested drugs are rarely a focus of attention in these trials. Moreover, treatment guidelines produced in North America and Europe are often regarded as universally valid, and rarely adapted to other regional contexts. This is still partly due to some reluctance to accept the concept of ethnic variability,... [Pg.198]

EPCRA22 is intended to help communities prepare to respond in the event of a chemical emergency, and to increase the public s knowledge of the presence and threat of hazardous chemicals. To this end, EPCRA requires the establishment of state and local committees to prepare communities for potential chemical emergencies. The focus of the preparation is a community emergency response plan that must... [Pg.473]

The autonomic nervous system (ANS), also known as the visceral or involuntary nervous system, functions below the level of consciousness. Because it innervates cardiac muscle, smooth muscle, and various endocrine and exocrine glands, this nervous system influences the activity of most of the organ systems in the body. Therefore, it is evident that the ANS makes an important contribution to the maintenance of homeostasis. Regulation of blood pressure gastrointestinal responses to food contraction of the urinary bladder focusing of the eyes and thermoregulation are just a few of the many... [Pg.91]

Robert Richards. So when you have those traits, which do not seem to have any purchase on success and reproduction, then I think you re perfectly right to be very sceptical about that, but take some other kinds of traits, something that is almost as ambiguous as rape. Because rape occurs under a lot of different conditions and in some cases you re not quite sure how to evaluate the behaviour and so on. But, as we were talking at coffee, what about maternal attachment Now that s a fairly vague concept as well. It is the kind of response a mother will have for an infant. That attachment, and again, very often vaguely described, but one can focus on particular aspects of it. Let me just ask you - do you think this is ripe for evolutionary analysis So that s the basic question. [Pg.244]


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See also in sourсe #XX -- [ Pg.56 ]




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