2- ethylhexyl lactate

CAS 186817-80-1 EINECS/ELINCS 228-503-2 Synonyms (S)-2-Ethylhexyl lactate L-Lactic acid, 2-ethylhexyl ester Propanoic acid, 2-hydroxy-, 2-ethylhexyl ester... 

Ethyl caproate Ethyl cinnamate Ethyl, crotonate Ethylcyclohexane Ethyl decanoate N-Ethyidiethanolamine Ethylenediamine Ethylene glycol dibutyl ether Ethylene glycol isobutyl ether Ethylene oxide 2-Ethylhexyl lactate 2-Ethylhexyl-S-lactate Ethyl octanoate Ethyl oleate Ethylsulfonylethyl alcohol Ethyl toluene Fenchyl alcohol Formaldehyde Fusel oil refined Glyceryl ricinoleate Heptane Heptyl alcohol n-Hexadecane Hexamethyidisilazane Hexamethylene diisocyanate... 

Lactates 2-Ethylhexyl Lactate 186817-80-1 235.4 Combustible Class IIIB or NOS ... 

Williams J, Foster PM. 1989. The effects of 1,3-dinitrobenzene and mono-(2-ethylhexyl) phthalate on hormonally stimulated lactate and pyruvate production by rat Sertoli cell cultures. Toxicol Lett 47 249-257. 

Di(2-ethylhexyl) phthalate (0, 0.5, 1, 2.5 or 5 g/kg per day) was administered to Fischer 344 rats by oral gavage from birth through lactation day 21 and the activity of several peroxisomal enzymes was determined in the livers, kidneys and brains of the females and their offspring (Cimini et al., 1994). No pups survived exposure to doses of 2.5 g/kg per day. Pup growth was impaired at the two lowest doses. In the liver, cyanide-insensitive palmitoyl-CoA oxidase activity showed similar increases in pups and adult females. 

Oral administration of di(2-ethylhexyl) phthalate at levels of 0, 250, 500 or 1000 mg/kg bw to adult albino rats for 15 days resulted in a significant decrease in sperm count in the epididymus and increased activity of P-glucuronidase, y-GT and lactate dehydrogenase and a decrease in the activity of acid phosphatase in the testes. The authors interpreted these findings as indicating germ-cell depletion and deterioration of the germinal epithelium in the testes (Parmar et al, 1986). 

Adult male albino rats received 0, 500 or 1000 mg/kg di(2-ethylhexyl) phthalate by gavage for 15 days and were killed 24 h later (Siddiqui Srivastava, 1992). Relative testis weight and epididymal sperm counts were reduced at the highest dose, as was the activity of several enzymes relevant to spermatogenesis (aldose reductase and sorbitol dehydrogenase). The activity of testicular lactate dehydrogenase was increased at this dose. 

The involvement of testosterone in the testicular atrophy caused by di(2-ethyl-hexyl) phthalate was examined by co-administration of testosterone (1 mg/kg bw) subcutaneously with 2000 mg/kg bw di(2-ethylhexyl) phthalate [purity not specified] in groundnut oil to adult male Wistar rats for 15 days (Parmar et al., 1987). Administration of di(2-ethylhexyl) phthalate reduced the sperm count and also significantly increased the activity of y-GT, lactate dehydrogenase and P-glucuronidase and decreased the activity of sorbitol dehydrogenase and acid phosphatase. Co-adminis-tration of testosterone seemed to normalize the sperm count and the activity of testicular enz5mies. The role of testosterone in the testicular toxicity of di(2-ethylhexyl) phthalate has not been fully elucidated. Several reports refer to increased or decreased testosterone levels in plasma and testicular tissue. 

Cittiini, A M., Sulli, A., Stefanini, S., Serafini, B., Moreno, S., Rossi, L., Gioigi, M. Cera, M R (1994) Effects of di-(2-ethylhexyl)phthalate on peroxisomes of liver, kidney and brain of lactating rats and their pups. Cell. mol. Biol., 40, 1063-1076 Cocchieri, R.A. (1986) Occurrence of phthalate esters in Italian packaged foods. J. Food Protect., 49, 265-266... 

Tan, G.H. (1995) Residue levels of phthalate esters in water and sediment samples from the Klang River Basin. Bull, environ. Contam. Toxicol., 54, 171-176 Tandon, R., Chowdhary, S.R., Seth, P.K. Srivastava, S.P. (1990) Altered development of testis of rat exposed to di(2-ethylhexyl) phthalate (DEHP) during lactation. J. environ. Biol, 11, 345-354... 

In a multigeneration study, rats were given 100 mg/kg di(2-ethylhexyl) adipate per day via the feed. For four sueeessive generations, no substanee-specific influence on reproduction rate, lactation or growth was reported [no further details supplied] (Le Breton, 1962, cited in BUA, 1996). 

Moss EJ, Cook MW, Thomas LV, et al. 1988. The effect of mono-(2-ethylhexyl) phthalate and other phthalate esters on lactate production by Sertoli cells in vitro. Toxicol Lett 40 77-84. 

EINECS 269-358-5 Toluene-2,4-dioarbamic acid, 2-(N,N-dimethylamlnoethyl) 4-(2-ethylhexyl) ester, lactate Lactic xid, compound with 3-(2-(dimethylamino)ethyl) 1-(2-ethylhexyl) toluene-... 

Ethyl formate average 2 -Ethyh 1 -hexanol 2-Ethylhexyl acetate Ethyl lactate... 

Classification Lactate ester Definition 2-Ethylhexyl ester of lactic acid Uses Solvent... 

Purasolv BL. See Butyl-(S)-lactate Purasol / EHL. See 2-Ethylhexyl-S-lactate Purasolv EL Purasolv ELECT Purasolv ELS. See Ethyl-(S)-lactate Purasolv IPL. See Isopropyl-S-lactate Purasolv ML. See Methyl-(S)-lactate Pure-BInd B910-, Pure-BInd B923. See Food starch, modified... 

Stearic acid, dodecyl ester. See Lauryl stearate Stearic acid ester with lactate of lactic acid calcium salt. See Calcium stearoyl lactylate Stearic acid, ester with lactic acid bimol. ester, sodium salt. See Sodium stearoyl lactylate Stearic acid, ethylenediamine diamide. See Ethylene distearamide Stearic acid, ethyl ester. See Ethyl stearate Stearic acid, 2-ethylhexyl ester. See Octyl stearate... 

Ethylhexyl methacrylate Ethyl lactate Ethyl methacrylate Ethyl triglycol methacrylate Feldspar... 

N,N,N, N -Tetramethyl-1,3-butanediamine Titanium acetylacetonate Triethylamine Zinc acetylacetonate catalyst, esterification Acetyl acetone Acetyl chloride Ammonium lactate Calcium acetate Cobalt diacetate Cumene sulfonic acid Ethylacetoacetate 2-Ethylhexyl titanate Fluoboric acid Lead acetate... 

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