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Ethylestrenol

Chemical Abstracts Registry No. 548-00-5 Trade Name Manufacturer [Pg.597]

Glyoxylic acid ethyl ester ethyl alcoholate Manufacturing Process [Pg.597]

7 g of benzotetronic acid are dissolved in 750 cc of water at boiling temperature and thereafter 10.5 g of glyoxylic acid ethyl ester ethyl alcoholate are added. After a short while the liquid becomes turbid and gradually a white deposit is separated. The deposit Is filtrated and dried in vacuo. The melting point is 172°C to 174°C after recrystallization from methyl alcohol 153°Cto 154 C. [Pg.597]

The crude product is dissolved in sodium lye, filtrated by means of animal charcoal precipitated by means of hydrochloric acid, and recrystallized from methyl alcohol. The melting point is 153°Cto 154°C. [Pg.597]

Rosicky, J. U.S. Patent 2,482,511 September 20,1949 assigned to Spojene Farmaceuticke Zovody (Czechoslovakia) [Pg.597]

Glyoxylic acid ethyl ester ethyi alcoholate Manufacturing Process [Pg.597]

Therapeutic Function Anabolic Chemical Name 19-nor-17a-pregn-4-en-17-ol Common Name 17a-ethyl-17(3-hydroxy-19-norandrostene Structural Formula  [Pg.597]

Trade Name Manufacturer Country Year Introduced [Pg.598]

5 grams of lithium cut to small pieces are added to 435 ml of dry ethylamine which is cooled in ice. After the solution turns blue 9 grams of 17a-ethyloestradiol-3-ethylether dissolved in 900 ml of dry ether are added. [Pg.598]

Subsequently, the reaction mixture is stirred at a temperature of 0° to 5°C for 20 hours, after which 50 ml of absolute ethanol are added. Then the ethylamine is distilled off at low pressure. To the remaining solution 50 ml of ether and 50 ml of water are added. The water layer is separated and extracted a few times with ether. The collected ether extracts are added to the ethereal layer, after which this ethereal solution is washed with a 2 N hydrochloric acid solution, subsequently with a saturated sodium bicarbonate solution, and then with water. The ethereal solution is then dried on sodium sulfate and finally evaporated to dryness. [Pg.598]

The crude product is distributed between equal parts of petroleum ether and 70% methanol. From the petroleum ether layer 5.6 grams of A -17ai-ethyl-17j3-hydroxy-19-nor-androstene with a melting point of about 50°C are obtained. [Pg.598]

Condensation of the lynestrol intermediate (47) with ethyl-magnesium bromide affords the oral androgen ethylestrenol (72) Animal experiments on the various drugs above have all shown increased anabolic effects relative to androgenicity. [Pg.170]

Bolasterone Ethylestrenol Fluoxymesterone Metenolone Acetate Methandros t enolone Nandrolone... [Pg.434]

Androstanolone Dromostanolone Propionate Ethylestrenol Fluoxymestrone Mesteralone... [Pg.435]

Ethyloestradiol-3-ethyl ether Ethylestrenol Ethyl orthoacetate lazoxide Ethyl orthoformate Formocortal acetate Norethindrone Oxendolone Ethyl oxalate... [Pg.1634]

CijH2fi02 434-22-0) see Allylestrenol Ethylestrenol Lynestrenol Methylestrenolone Nandrolone decanoate Nandrolone hexyloxyphenylpropionate Nandrolone phenylpropionate Nandrolone undecylate naphthalene... [Pg.2425]

Although some steroids have been reported to reduce the toxic effects of some insecticides, the steroid ethylestrenol decreased the rate of recovery of depressed cholinesterase activity in disulfoton- pretreated rats (Robinson et al. 1978). The exact mechanism of this interaction was not determined. Ethylestrenol alone caused a small decrease in cholinesterase activity, and, therefore, resulted in an additive effect. Rats excreted less adrenaline and more noradrenaline when given simultaneous treatments of atropine and disulfoton compared with rats given disulfoton alone (Brzezinski 1973). The mechanism of action of disulfoton on catecholamine levels may depend on acetylcholine accumulation. In the presence of atropine, the acetylcholine effect on these receptors increases the ability of atropine to liberate catecholamines. [Pg.125]

Robinson CP, Smith PW, Endecott BR. 1978. Depression of cholinesterase activity by ethylestrenol in organophosphorus-poisoned and normal rats. Toxicol Appl Pharmacol 44 207-211. [Pg.194]

Ethacrinic acid, 120 Ethambutol, 222 Ether cleavage, 314, 368 Ethionamide, 255 Ethisterone, 163, 172 Ethithiazide, 358 Ethoheptazine, 303 Ethopropazine, 373 Ethosuximide, 228 Ethotoin, 245 Ethoxysolamide, 327 Ethylestrenol, 170 Ethylmorphine, 287 Ethynodiol diacetate, 165, 186 Ethynodrel, 164 Ethynylestradiol, 162 Etonitazine, 325... [Pg.481]

See other pages where Ethylestrenol is mentioned: [Pg.267]    [Pg.237]    [Pg.597]    [Pg.597]    [Pg.1632]    [Pg.1695]    [Pg.1715]    [Pg.1726]    [Pg.1726]    [Pg.1726]    [Pg.804]    [Pg.804]    [Pg.804]    [Pg.2372]    [Pg.2381]    [Pg.2395]    [Pg.2428]    [Pg.2429]    [Pg.374]    [Pg.1585]    [Pg.461]    [Pg.27]    [Pg.568]    [Pg.967]    [Pg.1513]    [Pg.1513]    [Pg.1514]    [Pg.804]    [Pg.804]    [Pg.2372]   
See also in sourсe #XX -- [ Pg.804 ]

See also in sourсe #XX -- [ Pg.93 ]

See also in sourсe #XX -- [ Pg.72 , Pg.257 ]

See also in sourсe #XX -- [ Pg.145 ]

See also in sourсe #XX -- [ Pg.171 , Pg.172 ]

See also in sourсe #XX -- [ Pg.287 ]



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