Formocortal Acetate

Chemical Name 3-(2-chloroethoxy)-9-fluoro-11, 16a,17,21-tetrahydroxy-20-oxopregna-3,5-diene-6-carboxaldehyde, cyclic 16,17-acetal-21-acetate 

1 gram of this 9a-fluoro-5-pregnene-11)3,16a,17a,21-tetrol-3,20-dione-21-acetate-3-ethylene-ketal-16o,17a-acetonide in 2 cc of dimethylformamide and 2 cc of trichloroethylene was heated for 3 hours on an oil bath at 70°C with the reagent obtained from 0.5 cc of dimethylformamide in 4 cc of trichloroethylene with 0.5 cc phosphorus oxychloride. After cooling to 0°C, 1 gram of sodium acetate dissolved in 3 cc of water were slowly added with stirring. The mixture was extracted with ethyl acetate and the extracts were washed with 

Camerino,B., Patelli, B.and Sciaky, R. U.S. Patent 3,314,945 April 18,1967 assigned to Societa Farmaceutici Italia, Italy 

9a-Fluoro-4-pregnene-11/3,16a, 17a,21-tetrol-3.20-dione-21-acetate-16a, 17a-acetonide Ethylene glycol Ethyl orthoformate Trichloroethylene Phosphorus oxychloride 

3-ethyleneketal-16a,17a-acetonide, melting at 145° to 147°C, were collected from the fractions eluted with benzene-ether 9 1. 

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Ethyloestradiol-3-ethyl ether Ethylestrenol Ethyl orthoacetate lazoxide Ethyl orthoformate Formocortal acetate Norethindrone Oxendolone Ethyl oxalate... 

Fontego - Bumetanide Fonzylane - Buflomedil Forane Isoflurane Fordex - Tolbutamide Fordiuran Bumetanide Foreart Inosine Forenol -Niflumic acid Forhistal Dimethindene maleata Foristal - Dimethindene maleate Formaftil - Formocortal acetate Formulex Dicyclomine HCI Fortabol -Methenolona acetate Fortabolin - Nandrolone decanoate Fortapen - Ampicillin Fortasec - Loperamide HCI Fortecortin Dexamethasone acetate Fortesul Sulfameter... 

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