Ethanol solubility

Glutelins. Also insoluble in water and in 7% aqueous ethanol. Soluble in acids and alkalis. Also found in cereals. 

To produce highly purified phosphatidylcholine there are two industrial processes batch and continuous. In the batch process for producing phosphatidylcholine fractions with 70—96% PC (Pig. 4) (14,15) deoiled lecithin is blended at 30°C with 30 wt % ethanol, 90 vol %, eventually in the presence of a solubiHzer (for example, mono-, di-, or triglycerides). The ethanol-insoluble fraction is separated and dried. The ethanol-soluble fraction is mixed with aluminum oxide 1 1 and stirred for approximately one hour. After separation, the phosphatidylcholine fraction is concentrated, dried, and packed. 

Pig. 4. Batch process for producing phosphatidylcholine fractions. 1, Ethanol storage tank 2, deoiled lecithin 3, solubiHzer 4, blender 5, film-type evaporator 6, ethanol-insoluble fraction 7, ethanol-soluble fraction 8, aluminum oxide 9, mixer 10, decanter 11, dryer 12, aluminum oxide removal 13, phosphatidylcholine solution 14, circulating evaporator 15, cooler 16, dryer and 17, phosphatidylcholine. 

In the continuous process for producing phosphatidylcholine fractions with 70—96% PC at a capacity of 600 t/yr (Pig. 5) (16), lecithin is continuously extracted with ethanol at 80°C. After separation the ethanol-insoluble fraction is separated. The ethanol-soluble fraction mns into a chromatography column and is eluted with ethanol at 100°C. The phosphatidylcholine solution is concentrated and dried. The pure phosphatidylcholine is separated as dry sticky material. This material can be granulated (17). 

The chromatogram of the commercial soya lecithin as shown in Figure 4 suggests a number of components and all subsequent work was done with the ethanol-soluble fraction, i.e., phosphatidyl choline, or the ethanol-insoluble fraction, comprised primarily of other phosphatides. 

Chromatograms of the ethanol-soluble fraction were obtained in THF on Toyo Soda Oligomer columns over a range of sample masses, as shown in Figure 5 The exclusion limit of these columns is 50,000 and Mp" values above 10,000 are inaccurate because the calibration curve is very steep in this region. Consequently, chromatograms were also obtained on the "Main Column" GPC with the results shown in Figure 6. 

The dependence of Mp" on sample size for the ethanol-soluble fraction is sumnarized by the solid lines in Figure 7. For both column sets, the apparent MW of the principal peak increases by nearly an order of magnitude as the mass of the injected sample is increased from one to four mg. In contrast, the ethanol-insoluble fraction exhibits a rather narrow chromatogram... 

Figure 7. Effect of sample size on apparent molecular weight for soya lecithin phosphatide fractions (conditions same as for Figures 5 and 6 (O) ethanol-soluble fraction (phosphatidyl choline), oligomer GPC (%) ethanol-soluble fraction (phosphatidyl choline), "main column (l ) ethanol-insoluble fraction (other phos-p hat ides), "oligomer GPC (A) ethanol-insoluble fraction (other phosphatides),...

Solubility/miscibility Miscible with water and ethanol. Soluble in water and ether... 

Solubility/miscibility Insoluble in ethanol. Soluble to twice its weight (2 x grams) in water (xml). Soluble in glycerol and propylene glycol Biological considerations Virtually biologically inert Chemical compatibility/Stability considerations None Uses (routes) Orally, as diluent or viscosity increaser in solvents... 

Solubility/miscibility Insoluble in water and ethanol. Soluble in ether and oils Biological considerations Aspiration may cause lipoid pneumonia Chemical compatibility/Stability considerations Flammable Uses (routes) Oral, vaginal, rectal, dermal. Suspending agent... 

Solubility Water Organic solvents) 128 g/100 cc at 0 °C v soluble in hot water3 v soluble in ethanol soluble in acetone and methanol insoluble in ethyl acetate and chloroform11... 

Colorless gas (or fuming hquid) density 5.14 g/L hquefies at 12.6°C solidifies at -107°C vapor pressure 470 torr at 0°C critical temperature 182°C critical pressure 38.2 atm critical molar volume 239 cm /mol reacts with water and ethanol soluble in carbon tetrachloride. 

Pink rhombohedral crystals refractive index 1.855 density 4.13 g/cm decomposes on heating insoluble in water and ethanol soluble in acids. 

Color and form varies from blue crystals to greenish powder slightly soluble in water and ethanol soluble in dilute acids and ammonium hydroxide. 

The dihydrate exists as greenish blue orthorhombic crystals density 2.51 g/cm3 decomposes at 100°C is very soluble in water and ethanol (solubility greater than anhydrous salt in these solvents) also soluble in acetone insoluble in ether. 

Iron pentacarbonyl is a yellow oily hquid flammable density 1.490 g/mL freezes at -20°C boils at 103°C vapor pressure 40 torr at 30°C insoluble in water slightly soluble in ethanol soluble in acetone, ether, and benzene. 

Yellow hexagonal crystals density 6.16 g/cm melts at 402°C vaporizes at 954°C decomposes at 180°C when exposed to green light slightly soluble in water (0.44 g/L at 0°C and 0.63 g/L at 20°C) Ksp 8.49xlCL9 at 25°C partially soluble in boiling water (4.1 g/L at 100°C) insoluble in ethanol soluble in alkalis and alkali metal iodide solutions. 

The oxide exhibits two crystalline modifications, the reddish or orange-red alpha form, known as litharge, and the yellow beta form, massicot. The alpha form constitutes tetragonal crystals while the beta modification is a yellow amorphous powder of orthorhombic crystal structure. The alpha form is stable at ordinary temperatures, converting to the beta form when heated at 489°C density 9.35 g/cm (beta form) Moh s hardness 2 (alpha form) the oxide melts at 888°C vaporizes at 1,472°C with decomposition vapor pressure 1 torr at 943° C and 5 torr at 1,039°C practically insoluble in water (the solubdity of alpha form is 17 mg/L at 20°C and that of beta form 23 mg/L at 22°C) insoluble in ethanol soluble in dilute nitric acid and aUtahes. 

Colorless monoclinic crystals turns pink unstable in air density 2.228 g/cm3 at 17°C melts at 175°C decomposes in cold water and ethanol soluble in chloroform, benzene, nitrobenzene, and hot glacial acetic acid also soluble in concentrated hydrochloric acid. 

Colorless liquid burns with orange flame with green margin refractive index 1.5198 density 1.653 g/mL at 20°C insoluble in water slightly soluble in ethanol soluble in benzene, toluene, gasoline, and petroleum ether. 

Colorless transparent crystals or white granular or crystalline powder rhombohedral structure density 2.11 g/cm at 20°C melts at 334°C decomposes at 400°C evolving oxygen soluble in cold water, 13.3 g/lOOmL at 0°C highly soluble in boiling water, 247 g/lOOmL at 100°C lowers the temperature of water on dissolution very slightly soluble in ethanol soluble in glycerol and liquid ammonia. 

Brownish-black cubic crystals density 7.14 g/cm at 16°C begins to decompose around 200°C, decomposition becoming rapid at 250 to 300°C insoluble in water and ethanol soluble in acids and alkalis sparingly soluble in solutions of caustic alkalis insoluble in alcohol. 

The British Pharmacopoeia specifies the following solubility data for Cortisone acetate practically insoluble in water, soluble in 4 parts of chloroform, and in 300 parts of 96% ethanol, soluble in 1,4-dioxan, sparingly soluble in acetone, and slightly soluble in both ether and methanol [3,4]. 

As shown in Figure 6, proteins of the gluten complex can be separated by solubility differences into saline-soluble albumins and globulins, 70% ethanol-soluble glladlns, acetic acid-soluble glutenln, and an insoluble protein residue. 

Solubility Very soluble in water, benzene, diethyl ether, and ethanol soluble in methanol, tetrahydrofurfuryl alcohol, dimethylformamide, chlorinated hydrocarbons, and petroleum fractions (Budavari, 1996 Lide, 1997)... 

Solubility. Decomposes in water and ethanol soluble in benzene, carbon disulfide and carbon tetrachloride miscible with diethyl ether (Budavari, 1996) Vapour pressure-. 53 Pa at 20°C relative vapour density (air = 1), 4.88 (Verschueren, 1996)... 

The urea herbicides do not inhibit seed-germination to any extent, or the growth of nonphotosynthetic tissue, nor do they interfere with dark-fixation reactions. Monuron-treated bean-leaves which were fed 14C02 in the light, however, decreased in sucrose content (as percent of ethanol-soluble materials) from 70 to 2% in 72 hours.185 Most of the carbon-14 label... 

FR Huebner, JA Bietz. Improved chromatographic separation and characterization of ethanol soluble wheat proteins. Cereal Chem 70 506-511, 1993. 

H Wieser, W Seilmeier, HD Belitz. Reversed-phase high-performance liquid chromatography of ethanol-soluble and ethanol-insoluble reduced glutenin fractions. Cereal Chem 66 38-41, 1989. 

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