Ehrlich’s ascites tumor

Outline of purification scheme for UMP synthase from Ehrlich s ascites tumor cells of mice. 

Fig. 11. Changes in the body weight of Ehrlich s ascites tumor-bearing mice after treatment with antitumor drugs...

Table 10. Antitumor activity of 5-FU and vinyl-type polymeric drugs against Ehrlich s ascites tumor bearing mice"...

Okada, Y., and Tadokoro, J. (1962) Analysis of giant polynuclear cell formarion caused by HVJ virus from Ehrlich s ascites tumor cells. Exp. Cell Res. 26, 98-128. 

Osterreich, S., Schunck, H., Benndorf, R., Bielka, H. (1991). Cisplatin induces the small heat shock protein hsp25 and thermotolerance in Ehrlich ascites tumor cells. Biochem. Biophys. Res. Comm. 180,243-248. 

Agranofl, B. W., Hajra, A. K. The acyl dihydroxyacetone phosphate pathway for glycerolipid biosynthesis in mouse liver and Ehrlich ascites tumor cells. Proc. Natl. Acad. Sci. U.S. 68, 411-415 (1971). 

The carcinostatic action of 8-azaguanine against the Ehrlich ascites tumor in mice was potentiated by 4-aminoimidazole-5-carboxamide, which exerted a synergistic effect by preventing deamination. The toxicity exerted by 8-azaadenosine in mice was traced to its 5 -triphosphate, which replaced adenosine triphosphate in the host s hepatocytes. Phosphatidylcholine liposomes were studied as a suitable vehicle for conveying 8-azaguanine to leukemic cells. ... 

Tri phosph ate, C, 0H, 3 N sO, 2 P3, cordycepi ii 5 triph osphate 3 deoxy ATP. 3 deoxyadeltosine 5, dtetrahydrogen triphosphate) Inhibits the final step of RNA biosynthesis by termination of the ribonucleotide chain due to the absence of the 3 -hydroxyl group. Formation by conversion of 3 -de-oxyadeno ine in Ehrlich ascites tumor H. Klenow, Biochim. Biophys, Acta 76, 347 (1963), Metabolism in K.B cells H, Shigeura, S. Sampson, ibid, 138, 26 (1967). Synthesis J, J, Novak, F. Sorm. Coll Czech. Chem. Common, 38, 113 (1973) M, Blandin. / Carbahyd. Nuch, Nucl 3(5/6), 341 (1976). 

Hertz L., Schousboe A., Boechler N, Mukerji S., and Fedoroff S (1978) Kinetic characteristics of the glutamate uptake into normal astrocytes in culture Neurochem Res 3, 1-14 Hertz L., Yu A, Svenneby G, Kvamme E., Fosmark H., and Schousboe A. (1980) Absence of preferential glutamine uptake into neurons. An indication of a net transfer of TCA constituents from nerve endings to astrocytes Neurosct Lett 16, 103-109 Hoffman E K., Simonsen L O, and Lambert I H (1984) Volume-induced increase of K" and Cr permeabilities in Ehrlich ascites tumor cells Role of internal calcium / Membrane Biol 78, 211-222 Holloway P. W (1973) A simple procedure for removal of triton X-100 from protein samples Anal Biochem 53, 30 308 Hosli E. and Hosli L. (1976) Autoradiographic studies on the uptake of [ H] noradrenaline and [ H] GABA in cultured rat cerebellum Exp Brain Res 26, 319-324... 

Hornsey, S., and A. Howard. 1956. Autoradiograph studies with moxisQ Ehrlich Ascites tumor. Ann. N. Y. Acad. ScL, 63 915-928. 

Bredehorst R, Goebel M, Renzi F, Kittler M, Klapproth K, Hilz H (1979) Intrinsic ADP-ribose transferase activity versus levels of mono(ADP-ribose) protein conjugates in proliferating Ehrlich ascites tumor cells. Hoppe-Seyler s Z Physiol Chem 360 1737-1743... 

ABREU, S. and LUCAS-LENAEU, J. Cellulax protein synthesis shut-off by mengovirus Translation of nonviral and viral mRNAs in extracts from uninfected and infected Ehrlich ascites tumor cells. J. Virol. (1976), 18, 184-192. 

Agrawal SS, Saraswati S, Mathur R, Pandey M (2011) Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line. Life Sci 89(5-6) 147-158. doi 10.1016/j.lfs.2011.05.020... 

Isolated polypeptides, viscotoxins II, III, and IVb, have been associated with cardio-toxicity but have also been found to exhibit cytotoxic activity against human tumor cells of the KB and HeLa lines in tissue culture. A peptide with a molecular weight of 5000 was found to be cytotoxic to Dalton s lymphoma ascites tumor cells in vitro in mice, without affecting normal lymphocjfies, indicating a cell-dependent specificity also cyctotoxic to Ehrlich ascites cells, both prophylacticaUy and after tumor development. Commercial mistletoe products have been used to treat various cancers in Europe with clinical success. A group of 50 cases of carcinomatous pleural effusions were treated with a topical preparation for an average of 3.3 application over 18 days exudation disappeared in 92% of the patients. In postoperative ovarian cancer patients, a mistletoe preparation statistically increased survival. ... 

Xanthan gum has been reported to be active against Ehrlich ascites tumor and S-180 in mice, being synergistic with 5-fluorouracil or bleomycin in S-180. ... 

Gupta, S. L., Sopori, M. L., and Lengyel, P., 1974, Release of the inhibition of mRNA translation in extracts of interferon-treated Ehrlich ascites tumor cells by added tRNA, Biochem. Biophys. Res. Commun. 57 763. 

Characterization of amino acid transport in eukaryotic cells has received a great deal of attention during the last decade and, for the reasons already mentioned, the liver has been a popular choice as a model tissue. As a result, more information has been obtained for amino acid transport in rat hepatocytes than for any other cell type with the possible exception of the Ehrlich ascites tumor cell. Furthermore, although nine separate systems have been shown to mediate amino acid transport in isolated hepatocytes. System A has been studied in greater detail than any of the others. Despite the large number of descriptive investigations that have focused on hepatic System A, there are several areas of characterization that remain to be explored. Some of these must wait until isolation of the protein(s) responsible for System A activity makes them feasible, but several interesting studies can be undertaken at the cellular level as well. 

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