Drug delivery materials

However, it has to be realized that biological templates remain inserted in the final nanoparticles and this is not acceptable for many applications. Nevertheless, some recent examples indicate that such biomimetic materials may be suitable for the design of biotechnological and medical devices [32]. For instance, it was shown that silica gels formed in the presence of p-R5 were excellent host matrices for enzyme encapsulation [33]. In parallel, biopolymer/silica hybrid macro-, micro- and nanocapsules were recently obtained via biomimetic routes and these exhibit promising properties for the design of drug delivery materials (see Section 3.1.1) [34,35],... 

Potential applications of peptide-polymer conjugates include drug delivery materials, optoelectronics, biosensors, tissue scaffolds, tissue replacement materials, hydrogels, adhesives, biomimetic polymers, lithographic masks, and templates for metallic or silica nanostructures. 

Several comprehensive reviews on polymerizable lipids and supramolecular structures derived from them appeared between 1985 and 2002 [3,25-31], Consequently, this review focuses on developments in this field during 2000-2008. These include synthesis of new types of polymerizable lipids, creation and characterization of novel poly(lipid) membrane systems, and applications of polymerized vesicles and membranes in chemical sensing, separations science, drug delivery, materials biocompatibility, and other fields. 

Alginate is widely used in separation, food, textile, and paper applications. Moreover, due to its biocompatibility, alginate has been extensively used in the biomedical field as a drug delivery material [34, 35], a wound dressing [36], a scaffold [37, 38] and for cell encapsulation [39]. Therefore, the BC-alginate composite has been extensively studied in many fields. Comparative characteristics of BC-alginate composites prepared from various methods are shown in Table 14.1. 

The ability of some organic compounds to gel in organic and aqueous solutions has been a phenomenon that has received significant attention because of its application in separation science, drug delivery, materials science, sensing, and biomimetics. Gels are a well-known colloidal... 

Rutgers University has developed a new series of highly branched water-soluble polymers for use as controlled-release drug delivery materials. A series of polymers has been prepared that behave like unimolecular micelles. The polymers maintain the good characteristics of conventional micelles, but they are not sensitive to concentration changes in the body which can affect micelle integrity. The polymers are assembled from mucic acid, fatty acids and polyethylene glycol. 

This chapter discusses tile application of boronic adds as potential enzyme inhibitors, artificial lectins (boronolectins), feed-back controlled drug delivery materials, boron neutron capture therapy agents, and other biologically active agents. The discussion focuses on the underlying chemical principles important for the various applications using selected examples. It does not strive to be comprehensive in terms of covering all the literature reports in this area, for which one can consult various reviews already [9, 38-40]. Boronic acids have also been used for the transport of various compounds such as ribonudeosides [41], amino acids [42], catecholamine [43], and saccharides across membranes [44-47]. However, such applications are more aimed for purification and separation and, therefore, will not be addressed in detail in this chapter. 

Prior to any marine material can be used as a graft or drug delivery material, it must first undergo a rigorous process to test the composition, purity, morphology, and... 

The chapters Synthesis.. Properties... and Application.of aminothiophenes are well documented and written in clear language. The article is well structured to provide guidelines for mechanism, specific applications in drug delivery, material science or recent theories. The reader interested in the latter aspects can find further detailed information in the list of references. 

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