Applications and Uses

Atorvastatin calcium is used as an adjunct to diet to reduce the elevated total-cholesterol, LDL, apolipoprotein B (apo B), and triglyceride (TG) levels, and to increase the HDL-C level in patients with primary hypercholesterolemia and mixed dyslipidemia. The drug is also used for the treatment of patients with an elevated serum TG levels, and for the patients with primary dysbetaliproteinemia, which do not respond adequately to diet. Atorvastatin calcium is also indicated to reduce the total-cholesterol and LDL-C in patients with homozygous familial hypercholesterolemia (e.g., LDL apheresis) [6]. 

---

H. Walter, D. E. Brooks, and D. Eisher, eds.. Partitioning in Mqueous Tiro-Phase Systems Theory, Methods, Uses and Applications to Biotechnology, Academic Press, Inc., Orlando, 1985. 

Many different test systems have been used to investigate the ability of chemicals to interact with components of the endocrine system. The usefulness and applicability of the available methods has been the subject of much debate. Four key texts are particularly helpful in reviewing and giving guidance on currently available test methods and strategies for testing EDs. ... 

E. Lifshin. Scanning Electron Microscopy and X-Ray Analysis. Plenum Press, New York, 1981. Developed from a short course held aimually at Lehigh University. The book is concerned with the use and applications of SEM. In the latter context a lengthy discussion of EDS is given. The discussion... 

D. B. Williams. Practical Analytical Electron Microscopy in Materials Science. Verlag Chemie International, Weinheim, 1984. A good monograph discussing the use and applications of AEM, especially at intermediate voltages. The discussion on EDS is an excellent primer for using X-ray analysis on a TEM. 

Parts I and II. John Wiley and Sons, New York, 1987. An excellent description of the fundamental concepts, instrumentation, use, and applications of ICP-OES. 

The exterior hoods described here are divided into basic openings, rim exhausts, low-volume high-velocity (LVHV) hoods, receptor hoods (canopy hoods), and downdraft ventilation tables. Many varieties of these types of hoods exist. Some of these have been described and investigated more thoroughly than others because they are used more often or they are of more general use and applicability than the more specialized hoods. 

Having thus outlined tiie fcnmal theoretical structure of one-dimensional LST, we now turn to a more pragmatic discussion of its use and applications. 

New types of ion exchange resins have also been developed to meet the specific needs of high-performance liquid chromatography (HPLC) (Chapter 8). These include pellicular resins and microparticle packings (e.g. the Aminex-type resins produced by Bio-Rad). A review of the care, use and application of the various ion exchange packings available for HPLC is given in Ref. 19. 

The use of initiators such as 68 has been promoted for achieving higher molecular weights or higher conversions in conventional polymerization and for the production of block and graft copolymers. The use and applications of multifunctional initiators in the synthesis of block and graft copolymers is briefly described in Section 7.6.1. 

For the most part, DCA chemistries are researched by large international chemical corporations, but the various in-field uses and applications generally are developed by service companies, often in cooperation with friendly end-user customers. 

The patient or family member demonstrates an understanding of the use and application of the prescribed or recommended drug. 

The widespread use and applicability, however, can be directly attributed to the deep understanding of the fundamental properties associated with these elements and their attendant compounds. The fundamental research conducted with these elements forms the foundation upon which all applications and utility are built. The present Structure and Bonding volume is part of a three-part series focused on fundamental, biological, and applied aspects of the group 13 elements. It will showcase four new areas of fundamental work that will either grow in importance in the coming years, or provide new insight into potentially new areas. 

Simply producing reference materials is not enough they have to be used properly. Chapter 7 reviewed the proper use of RMs, but unless RMs and CRMs can be easily obtained and moved from one country to another without delays, duty or unnecessary controls, their use will be inhibited. Likewise, information about the materials that are available, their use, and their application should be freely available if analysts are to make informed decisions about the selection and use of a RM or CRM. It has already been made clear in previous Chapters that the correct choice of reference material for a particular application requires not only information about the RM, which is relatively easily available, but also information about the uses and applications of the reference material. Unfortunately, neither the availability of information about the reference materials and their uses nor their free movement across national borders are at all satisfactory. 

Gas and liquid chromatography directly coupled with atomic spectrometry have been reviewed [178,179], as well as the determination of trace elements by chromatographic methods employing atomic plasma emission spectrometric detection [180]. Sutton et al. [181] have reviewed the use and applications of ICP-MS as a chromatographic and capillary electrophoretic detector, whereas Niessen [182] has briefly reviewed the applications of mass spectrometry to hyphenated techniques. 

Moisture converts it to highly shock-sensitive xenon oxides [1], Precautions necessary for various aspects of its use and application are detailed [2,1,1,5],... 

There are many reference sources that expand the knowledge of polymer composition, uses and applications. These include scientific encyclopaedias (often arranged in an alphabetic manner), together with speciality books — especially on how additives improve and extend the uses of polymers. 

---