Drug delivery systems biomedical materials

Vegetable oil-based hyperbranched polymers have considerable potential in biomedical applications. This is due to their unique structural characteristics along with their biodegradability and biocompatibiUty. Preliminary studies show that vegetable oil-based hyperbranched polyurethanes have the potential to be used as biomaterials in biomedical applications such as drug delivery systems, biomedical smart materials and catheters. ... 

Phosphazene polymers can act as biomaterials in several different ways [401, 402,407]. What is important in the consideration of skeletal properties is that the -P=N- backbone can be considered as an extremely stable substrate when fluorinated alcohols [399,457] or phenoxy [172] substituents are used in the substitution process of the chlorine atoms of (NPCl2)n> but it becomes highly hydrolytically unstable when simple amino acid [464] or imidazole [405-407] derivatives are attached to the phosphorus. In this case, an extraordinary demolition reaction of the polymer chain takes place under mild hydrolytic conditions transforming skeletal nitrogen and phosphorus into ammonium salts and phosphates, respectively [405-407,464]. This opens wide perspectives in biomedical sciences for the utilization of these materials, for instance, as drug delivery systems [213,401,405,406,464] and bioerodible substrates [403,404]. 

NeubergerT, Schopf B, Hofmann H, Hofmann M, von Rechenberg B (2005) Superparamagnetic nanoparticles for biomedical applications possibilities and limitations of a new drug delivery system. Journal of Magnetism and Magnetic Materials 293 483 196. 

Significant developments have occurred in recent years in the fields of biopolymers and biomaterials. New synthetic materials have been synthesized and tested for a variety of biomedical and related applications from linings for artifical hearts to artifical pancreas devices and from intraocular lenses to drug delivery systems. Of particular interest in the future is the development of intelligent polymers or materials with special functional groups that can be used either for specialty medical applications or as templates or scaffolds for tissue regeneration. 

Chasin, M. andLanger,R. (eds) (1990) Biodegradable Polymers as Drug Delivery Systems. Marcel Dekker, New York. Tsirita, T., Hayashi, T., Ishihara, K., Kataoka, K. and Kimura, Y. (eds) (1993) Biomedical Applications of Polymeric Materials. CRC Press, Boca Raton, Florida. 

Business Communications Company, Inc. (BCC). 25 Van Zant St., Norwalk, CT 06855, U.S.A. Phone +1 203-853-4266, Fax +1 203-853-0348. E-mail editor buscom.com. URL http // www.buscom.com. Provides industry research and technical market analysis in many industries, including advanced materials, biotechnology/life sciences, nanotechnology, and plastics/polymers. All reports are available online. Recent report titles include Biocompatible Materials for the Human Body, Patient Monitoring Devices, Biomedical Applications of Nanoscale Devices, and Advanced Drug Delivery Systems New Development, New Technologies. 

The increasing strong interest in biodegradable materials for drug delivery systems and other biomedical uses, as well as for environmental applications, prompted us to evaluate their enzymatic degradation. 

Allcock, H.R., Polyphosphazenes as new biomedical and bioactive materials, in M. Chasin and R. Langer, Biodegradable Polymers as Drug Delivery Systems, New York Marcel Dekker, 1990 pp. 163-193. 

Drug delivery systems 2. Biomedical materials. I. Title. II. Topics in chemical engineering (Oxford University Press)... 

Stimuli-responsive polymers have gained increasing interest and served in a vast number of medical and/or pharmaceutical applications such as implants, medical devices or controlled drug delivery systems, enzyme immobilization, immune-diagnosis, sensors, sutures, adhesives, adsorbents, coatings, contact lenses, renal dialyzers, concentration and extraction of metals, for enhanced oil recovery, and other specialized systems (Chen and Hsu 1997 Chen et al. 1997 Wu and Zhou 1997 Yuk et al. 1997 Bayhan and Tuncel 1998 Tuncel 1999 Tuncel and Ozdemir 2000 Hoffman 2002 en and Sari 2005 Fong et al. 2009). Some novel applications in the biomedical field using stimuli-responsive materials in bulk or just at the surface are shape-memory (i.e., devices that can adapt shape to facilitate the implantation and recover their conformation within the body to... 

Bajpai P.K. 1994. Ceramic drug delivery systems. In Biomedical Materials Research in The Far East (I). Xingdong Zhang and Yoshito Ikada (Eds.), pp. 41 2. Kobunshi Kankokai Inc., Kyoto, Japan. 

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