Non-Domestic Substances List NDSL

The Canadian new chemicals program uses two chemical inventories, the Domestic Substances List (DSL) and the Non-Domestic Substances List (NDSL). The DSL includes substances that were, between January 1, 1984, and December 31, 1986, in Canadian commerce, used for manufacturing purposes, or manufactured in or imported into Canada.17 It contains about 23,000 substances. One of the initiatives in the Canadian Environmental Protection Act, 1999 (CEPA, 1999) requires the Minister of the Environment and the Minister of Health to categorize (Section 73, CEPA 1999) and then if necessary, conduct screening assessments (Section 74, CEPA 1999) of substances listed on the DSL to determine whether they are toxic or capable of becoming toxic as defined in the Act. The NDSL is a list of substances not on DSL but in commerce elsewhere in the world.18 The NDSL contains more than 58,000 entries. 

New chemical substances are all those not on the Domestic Substances List (DSL), which is a list of substances in commerce in Canada at >100 kg a from 1 January 1984 to 31 December 1986. If a new substance is on the Non-Domestic Substances List (NDSL), the information required for the notification is considerably less than for a standard notification. The NDSL, which is the 1985 US TSCA Inventory (as amended) minus the substances on the DSL, attempts to take account of established substances which did not happen to be sold in Canada during the period for inclusion in the DSL. The first DSL [33] and NDSL [34] were both publish in the Canada Gazette on 26 January 1991, and these inventories will be updated and corrected periodically when necessary. Most polymers are represented on the inventories in terms of the starting materials from which they are manufactured, and products of biotechnology will be included subsequently if necessary when their regulatory controls have been finalised. The DSL and NDSL contain confidential sections, which can be searched by Environment Canada if a bona fide intent to manufacture or import is established by submitting specified data. 

CAS Registry Numbers are also widely used as standard identifiers for chemical substances in many of the commercial chemical inventories of governmental regulatory agencies, such as the Toxic Substances Control Act (TSCA) Inventory in the United States, the European Inventory of Existing Commercial Chemical Substances (EINECS), and the Canadian Domestic and Non-Domestic Substance Lists (DSL/NDSL). 

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