Domains transcription factor

Rosenfeld, M.G. POU-domain transcription factors pou-er-ful developmental regulators. Genes Dev. 5 897-907, 1991. 

Both MOZ and MORF have also been linked to control of transcription. In initial analyses, these MYST HATs were found to contain potent trans-activation domains in their C-termini (Champagne et al, 1999 2001). Follow-up studies demonstrated that the two proteins can indeed function as transcriptional co-activators for two Runt-domain transcription factors - Runxl and 2 (also referred to as AMLl 3) (Kitabayashi et al., 2001a Pelletier et al., 2002). Furthermore, MORF has been found in the co-activator complex associated with the peroxisome proliferator-activated receptor alpha in rat liver (Surapureddi et al., 2002). 

AC VIII, adenylyl cyclase type VIII BDNF, brain-derived neurotrophic factor CamKII, calcium-calmodulin kinase II GIRK2, G protein-activated inward rectifying potassium 2 MAOA, monoamine oxidase A n.d., not determined NCAM, neural cell adhesion molecule nNOS, neuronal nitric oxide synthase Petl, ETS domain transcription factor tPA, serine protease tissue-plasminogen activator (tPA). t/ > Increase/decrease in anxiety-related behavior. No effect. 

Pfaar H, von Holst A, Vogt Weisenhorn DM, Brodski C, Guimera J, Wurst W (2002) mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons. Dev Genes Evol 212 43-46... 

Clyne P. J., Certel S., de Bruyne M., Zaslavsky L., Johnson W., Carlson J. R. (1999) The odor-specificities of a subset of olfactory receptor neurons are governed by acj6, a POU domain transcription factor. Neuron 22, 339-347. 

Pet-1 is an ETS-domain transcription factor that was first discovered in adrenal chromaffin-derivd PC 12 cells, where it was found to induce transcription of the nicotinic acetylcholine 34 receptor (175). Pet-1 is expressed in the adrenal medulla as well as the eye and the brain (175) within the brain, it is expressed exclusively in serotonin neurons (176,177). Pet-1 expression appears... 

Overexpression of the jasmonate-responsive AP2/ERF-domain transcription factor ORCA3 resulted in elevated levels of tryptophan and tryptamine, and, upon feeding of a terpenoid precursor, elevated levels of certain TIAs [91]. 

Fig. 8. Models showing the involvement of AP2/ERF-domain transcription factors in regulation of stress and defense gene expression in plants. The stress signal is perceived by interaction with a receptor (-kinase). Induction of de novo synthesis and/or modulation of the preexisting AP2/ERF-domain transcription factor activate gene expression. Unidentified signal transduction components are indicated with a question mark. Dashed arrows indicate the possible involvement of multiple signalling steps...

MENKE, F.L., CHAMPION, A., KUNE, J.W., MEMELINK, J., A novel jasmonate- and elicitor-responsive element in the periwinkle secondary metabolite biosynthetic gene Str interacts with a jasmonate- and elicitor-inducible AP2-domain transcription factor, ORCA2. EMBOJ., 1999,18, 4455-4463. 

VAN DER FITS, L., MEMELINK, J., The jasmonate-inducible AP2/ERF-domain transcription factor ORCA3 activates gene expression via interaction with a jasmonate-responsive promoter element. Plant J., 2001,25,43-53. 

Gonzalez, M. M. and Carlberg, C. (2002) Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors. J. Biol. Chem. 277, 18501-18509. 

The PAS domain transcriptional factor AhR is a nonnuclear receptor xenobiotic receptor. In the early 1990s, the AhR and its partner Ah receptor nuclear translocator (Arnt) protein were identified as a transcriptional sensor mediating the induction of CYP1A and 1B1 genes by dioxin and related polycyclic aromatic hydrocarbons [62, 63],... 

Millane RC, Kanska J, Dufiy DJ, Seoighe C, Cunningham S, Plickert G, Prank U. Induced stem cell neoplasia in a cnidaria by ectopic expression of a POU domain transcription factor. Development. 2011 138 2429-39. 

An early study on differential gene expression between 4 day heat stressed embryogenic and non-embryogenic microspores of rap>eseed identified five different cDNAs that were up regulated in the induced microspores (BoutiUer et al. 2002). Two of these encoded BURP domain proteins with unknown function (Hattori et al. 1998), the third encoded an AP2/EREBP domain transcription factor which has since been named BABY BOOM (BBM), the fourth cDNA encoded the orthologue of the Arabidopsis AKTl K+ channel protein (Sentenac et al. 1992), while the last sequence was one to which no ofjen reading frame had... 

JJ (2001) LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development. Proc Natl Acad Sci USA 98 11806-11811. 

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