Document type 24 -> Original

The document types that may be stored within the system may have a wide variety of file formats and sources, and range from just key documents to the totality of documents generated for a project. Eor each type of document stored in the EDMS, it is important to define the original version (i.e., as paper or electronic). 

The EPO esp cenet (ep.espacenet.com) database contains more than 60 million patents from 85 conntries worldwide (not just European Convention countries). The database is searchable by application number, assignee, inventor, or keywords from the title or abstract. Chemical structure searches are not possible. Patents can be viewed as images of the original document in PDF format one page at a time, or the whole patent can be viewed as a text document. Instantaneous translation from French or German into English is available for the latter document type if required. Equivalent pnblished patents, if any, are also listed and are available in PDF format. The text documents do not show chemical structures or diagrams, but these can be viewed in PDF format if required. 

The arrangement of the abstracts within any one section in Chemical Abstracts is determined by the original document type (first, abstracts of journal articles, including citation of review articles, then abstracts about technical reports, deposited documents and dissertations, followed by announcements of new books and, finally, patent abstracts). The abstracts under the various document headings are arranged according to the content of the original publication (Subsections). 

Throughout the standard, various clauses reference the clause on quality records. To avoid repetition, the common requirements for quality records are assembled under one heading. The requirements, however, are not limited to those clauses in which this requirement is referenced as many other clauses refer to records. However, as all clauses will generate some documentary evidence it should not be assumed that all such documents are quality records. The requirements, however, apply only to original records and not to any copies other than those taken for security reasons or copies of subcontractor records. There are several types of document used in a quality system and only some are classified as quality records. As quality records are documents it might be assumed that the requirements of clause 4.5 on document and data control apply to quality records. As clause 4.16 is not cross referenced in clause 4.5 (except for clause 4.5.2.2), there is clearly no requirement for you to apply the requirements for document control to quality records. (See also Part 2 Chapter 5.) Figure 5.2 illustrates the difference between quality records and documents. 

G6PD deficiency occurs in two common types in different populations. A severe deficiency occurs in people of Mediterranean origin a much less severe deficiency occurs in people of African origin. As this book documents,... 

The documentation of all the available types of data in the archives was done and tabulated to decide which information could be verified. Tournigan incorporated only those holes in the database which could be verified from original documentation. 

The usage of whole rock data has, however, its ambiguities. Estimates of original magmatic 8 0-values is best achieved through analysis of unaltered phenocrysts within rocks. Laser-based extraction methods on small amounts of separated mineral phases have documented subtle, but resolvable differences among different types of basaltic lavas (EUer et al. 1996, 2000 Dorendorf et al. 2000 Cooper et al. 2004 Bindeman et al. 2004, 2005, and others). 

The Sevillian production center is by far the most represented group in Gran Canaria. Moreover, it is very heterogeneous in terms of types of pottery documented. In addition to lusterware, Sevillan white (n = 9), Columbia simple (n = 4), Blue-on-white (n = 4), Ichtuknee blue-on-blue (n = 3), and Isabela polychrome (n = 1) are the other majolica types identified. In addition, one blue tile also has a Sevillan origin. A special case is raised by one sample, MJ0289, classified as Delft. 

Folders. Inside the main folder, you should provide five folders, Administrative (admin), Chemistry, Manufacturing and Controls (cmc), Pharmacology and Toxicology (pharmtox), Clinical (clinical), and Other (other) to organize the documents and data sets provided in the original submission and subsequent amendments to your IND (Fig. 4.1). See Table 4.1 for the types of documents that would reside in each folder. In addition, the main folder should contain an indindex folder (see Folder and File Names ). 

Cloth made from the inner bark (secondary phloem) of various plants is found throughout many of the tropical regions of the world. Although the origins of its production are unknown, they have been chronicled as early as the 6th-century B.C. in China (5). The bark cloth of the Pacific, more commonly referred to by the Polynesian word "tapa", has been produced from the inner bark of various species of trees of the genera Broussonetia R. (paper-mulberry), Artocarous (breadfruit), and Ficus (fig species) (6). While examples of each of these types are well documented, the... 

Transparent documentation of numerical values may depend on how the numbers were originally generated. Numerical values estimated from a population-based measurement study should describe the study design in detail, the basis for the population sample selected for measurement, how measurements were performed, how values were stored, how statistical summaries of the stored values were calculated, and so on. In other cases, a numerical value in an exposure assessment may be a value that is not associated with any particular data set but has been mandated by regulation or science policy or developed from theory. In this case, transparency requires a description of the source of the value, the types of situations or populations for which it was thought to be relevant and appropriate, any limitations of the value, and the degree and type of uncertainties associated with its use in a particular assessment. 

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