DNA double-strand break repair

Hopfner, K. P., Karcher, A., Shin, D. S., Craig, L., Arthur, L. M., Carney, J. P. and Tainer, J. A. (2000). Structural biology of Rad50 ATPase ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily, Cell, 101, 789-800. 

Hendrickson, E.A., 1997, CeU-cycle regulation ofmammalian DNA double-strand-break repair, Am.J.Hum.Genet. 61 795-800. 

Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J (2005) gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell 20 801-809. 

Wiltshire TD, Lovejoy CA, WangT et al (2010) Sensitivity to polyADP-ribose polymerase PARP inhibition identifies ubiquitin-specific peptidase 11 USPll as a regulator of DNA double-strand break repair. J Biol Chem 285 14565-14571... 

Bruso CE, Shewach DS, Lawrence TS. Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells. Int J Radiat Oncol Biol Phys 1990 19 1411-1417. 

Nlbrln, a novel DNA double-strand break repair protein, Is mutated In Nijmegen breakage syndrome... 

Rashid R, Langfinger D, Wagner R, Schuchmann H-P, von Sonntag C (1999) Bleomycin vs. OH-radi-cal-induced malonaldehydic-product formation in DNA. Int J Radiat Biol 75 110-109 Rothkamm K, Lobrich M (2003) Evidence for the lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc Nat Acad Sci USA 100 5057-5082 Sapora O, Fielden EM, LoverockPS (1975) The application of rapid lysis techniques in radiobiology. I. The effect of oxygen and radiosensitizers on DNA strand break production and repair in E. coli B/r. Radiat Res 64 431-442... 

Kanaar R, Hoeijmakers JH, van Gent DC. (1998) Molecular mechanisms of DNA double strand break repair. Trends Cell Biol 8 483-489. 

Hopfner KP, Karcher A, Craig L, Woo TT, Carney JP, Tainer JA. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mrell nuclease and Rad50-ATPase. 37. Cell 2001 105(4) 473-485. 

Cahill D, Connor B, Carney JP. Mechanisms of eukaryotic DNA double strand break repair. Front Biosci. 2006 11 1958-1976. 

Takata M, Sasaki MS, Sonoda E, Morrison C, Hashimoto M, Utsumi H, Yamaguchi-Iwai Y, Shinohara A, Takeda S. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 1998 17 5497-5508. 

Riha K, Heacock ML, Shippen DE. The role of the nonhomologous end-joining DNA double-strand break repair pathway in telomere biology. Annu. Rev. Genet. 2006 40 237-277. 

Verkaik NS, Esveldt-van Lange RE, van Heemst D, Bruggenwirth HT, Hoeijmakers JH, Zdzienicka MZ, van Gent DC. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells. Eur. J. Immunol. 2002 32 701-709. 

BRCA1 interacts specifically with the Rad51 protein which catalyzes strand exchange during recombination processes. By this property, BRCA1 is assumed to participate in DNA double-strand break repair. Furthermore, BRCA1 shows a DNA-binding activity specific for branched DNAs. 

Gorbunova, V., Levy, A.A. 1999. How plants make ends meet DNA double strand break repair. Trends Plant Sci 4 263-269. 

Shrivastav, M., De Haro, L.P., Nickoloff, J.A. 2008. Regulation of DNA double-strand break repair pathway choice. Cell Res 18(1) 134—147. 

Grawunder, U., Zimmer, D., Fugmann, S., Scharz, K., and Lieber, M. (1998). DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol. Cell 2, 477-484. 

Li, Z., Otevrel, T., Gao, Y., Gheng, H., and Seed, B. (1995). The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell 83, 1079-1089. 

Moshous, D., Callebaut, I., de Chasseval, R., Comeo, B., Cavazzana-Calvo, M., Le Deist, F., Tezcan, L, Sanal, O., Bertrand, Y., Philippe, N., Fischer, A., and de Villartay, J. (2001). Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. CeU 105, 177-186. 

Visualization of DNA Double-Strand Break Repair at the Single-Molecule Level... 

Gene expression in benzene-exposed workers by microarray analysis of peripheral mononuclear blood cells induction and silencing of CY-P4F3A and regulation of DNA-dependent protein kinase catalytic subunit in DNA double strand break repair. Chem Biol Interact 184 207-211... 

Chen L, Nievera CJ, Lee AY et al (2008) Cell cycle-depen-dent complex formation of BRCAl.CtlP.MRN is important for DNA double-strand break repair. J Biol Chem 283 7713-7720... 

Wyman C, Kanaar R (2006) DNA double-strand break repair all s well that ends well. Annu Rev Genet 40 363-383... 

Werbrouck J, De Ruyck K, Duprez F, Van Eijkeren M, Rietzschel E, Bekaert S, Vral A, De Neve W, Thierens H. Singlenucleotide polymorphism in DNA double-strand break repair genes association with head and neck cancer and interaction with tobacco use and alcohol consumption. Mutat Res 2008 656(1) 74-81. 

Kadhim, M.A., Lorimore, S.A., Hepburn, M.D., et al., 1994. a-Particle-induced chromosomal instability in human bone marrow cells. Lancet 344, 987-988. Kavanagh, J.N., Redmond, K.M., Schettino, G., et al., 2013. DNA double strand break repair a radiation perspective. Antioxid. Redox Signal. 18 (18), 2458-2472. 

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