Dimethyl methyl phosphate

Feng et al. [112] reported the nse of dimethyl methyl phosphate (DMMP) as a nonflammable solvent. The basic properties of DMMP are between those of TMP... 

Dimethyl sulfide, CH3SO3H. Methyl phosphates are selectively cleaved in the presence of other alkyl phosphates. ... 

Plant. Metabolites identified in cotton leaves include dimethyl phosphate, phosphoric acid, methyl phosphate, and CTdimethyl dichlorvos (Bull and Ridgway, 1969). The estimated half-life of dichlorvos applied to selected ornamental flower crops is 4.8 h (Brouwer et al, 1997). 

Plant. In cotton leaves, the metabolites identified included dichlorvos, phosphoric acid, 0-demethyl dichlorvos, 0-demethyl trichlorfon, methyl phosphate, and dimethyl phosphate (Bull and Ridgway, 1969). Chloral hydrate and trichloroethanol were reported as possible breakdown products of trichlorfon in plants (Anderson et al, 1966). 

At this point it is profitable to consider the hydrolysis or alcoholyses of the cyclic oxyphosphoranes themselves. The trimethoxyphospholene (37) undergoes a nearly instantaneous reaction with one molar equivalent of water in benzene solution at 0°C101. The products of this reaction are mainly dimethyl phosphoracetoin and the cyclic methyl phosphate of acetoinenediol, viz-... 

One embodiment of this general reaction led to a product which was commercially produced for several years by Stauffer as Fyrol 76 (9), a copolycondensation product of dimethyl methyl-phosphonate with bis(2-chloroethyl) vinylphosphonate. The features of Fyrol 76 were high phosphorus content (20%), water solubility, and ability to be polymerized by means of a radical initiator to a crosslinked polymer. A related polycondensation product was developed from tris(2-chloroethyl) phosphate and dimethyl methylphosphonate. By control of the reagents and procedure used for neutralization, these oligomeric products were produced with primary alcohol functional groups (7). 

Selective demethylotion. Alkyl methyl phosphates undergo demethylation when treated with dimethyl sulfide or ethanethiol and methanesulfonic acid (equation I). The products are isolated as the aniline salts. 

DIMETHYL METHOXYCARBONYLPROPENYL PHOSPHATE DIMETHYL (1-METHOXYCARBOXY-PROPEN-2-YL)PHOSPHATE 0,0-DIMETHYL 0-(l-METHYL-2-CARBOXYV1NYL) PHOSPHATE DURAPHOS ENT 22,374 FOSDRIN GESFID GESTID 3-HYDROXYCROTONIC ACID METHYL ESTER DIMETHYL PHOSPHATE MENIPHOS MENITE O (2-METHOXYCARBONYL-l-METHYL-VINYL)-DIMETHYL-FOSFAAT (DUTCH) (2-METHOXYCARBONYL-l-METHYL-VINYL)-DIMETHYL-PHOSPHAT (GERMAN) 2-METHOXYCARBONYL-l-METHYLVINYL DIMETHYLPHOSPHATE 1-METHOXYCARBONYL-1-PROPEN-2-YL DIMETHYL PHOSPHATE (l-METHOXYCARBOXYPROPEN-2-YL)PHOSPHORIC ACID, DIMETHYL ESTER METHYL-3-... 

O, 0-DIMETHYL-0-2-METH0XYCARB0NYL-1 -METHYL-VINYL-PHOSPHAT (GERMAN) see MQR750 DIMETHYL 2-METHOXYCARBONYL-l-METHYLVINYL PHOSPHATE see MQR750 DIMETHYL METHOXYCARBONYLPROPENYL PHOSPHATE see MQR750... 

Delpuech et al. (106) examined the tetrahedral solvates of the beryllium cation with trimethyl phosphate (TMPA), dimethyl methyl phosphonate (DMMP), N,iV-dimethylamido-0,0 -dimethyl phosphate (DMADM P), bis-A,iV-dimethylamido-0-methyl phosphate (TMDAMP), and hexamethylphosphorotriamide (HMPT) by NMR including that of Be. The kinetics of ligand exchange ... 

In humans and animals, the absorption, distribution, and excretion of trichlorfon is rapid. The biological half-life of trichlorfon in mammalian blood is estimated to be 30 min. It eliminates from the blood stream within a matter of 1.5 h, and only low levels are detected after 8-24 h. In mice, 70-80% of an oral dose of trichlorfon gets excreted within the first 12 h. Trichlorfon undergoes transformation via dehydrochlorination to form dichlorvos in all biological fluids and tissues. The major metabolites of trichlorfon found in vivo are demethyl trichlorfon, demethyl dichlorvos, dimethyl hydrogen phosphate, methyl hydrogen phosphate, phosphoric acid, and trichloroethanol. The excretion of trichlorfon and its metabolites occurs primarily via the urine. 

P-O bond fission is the usual mode of attack by nucleophiles on phosphodiesters, although there are exceptions. The labile diester methyl-2,4-dinitrophenyl phosphate shows significant amounts of attack at aromatic carbon (nucleophilic aromatic substitution, with loss of methyl phosphate) in competition with attack at phosphorus, most notably with hydroxide and with primary amines.46 Due to the small size of the methyl group it is sterically susceptible to nucleophilic attack in phosphate esters the hydrolysis of the dimethyl phosphate anion occurs almost exclusively by C-O bond fission.4 With larger or less labile leaving groups, even... 

The preparation of dimethyl (carbamoylmethyl) phosphate and bis (carbamoylmethyl) methyl phosphate from ammonia and the corresponding ester precursor are Illustrated in Eq. 3a and 3b of Fig. 11. Details of their preparation are described in reference... 

Stereospecific syntheses have been reported for ethyl isopropyl methyl phosphate, O-ethyl 0,S-dimethyl phosphorothioate, and ethyl methyl methyl-phosphonate,"" " and optically active alkyl S-methyl methyl phosphonothioates and dialkyl S-methyl methyl phosphorothioates have been prepared from ephedrine-RPSCU starting materials."" Finally, optically active phosphines can be obtained when a racemic phosphine oxide such as MePr"PhPO or (97) is reduced with a chiral, non-racemic aluminium hydride." "... 

A new method for the selective demethylation of alkyl methyl phosphates employs a mixture of dimethyl sulphide and methanesulphonic acid. Boron trifluoride etherate catalyses the regio- and stereo-specific alkenylation of phenolic ethers by diisopropyl prenyl or geranyl phosphates (84) in low to moderate yields. 2-(Diethoxyphosphinyl)-1,3-butadienes, e.g., (85), are cleaved by organocopper reagents in some cases this reaction is accompanied by alkylation and rearrangement to an allene structure. ... 

PhP = phenyl phosphate, p-Tyr = 0-phospho-L-tyrosine, MeP = methyl phosphate, diMeP = dimethyl phosphate, ATP = adenosine 5 -triphosphate, ADP = adenosine 5 -di-phosphate, AMP = adenosine 5 -monophosphate, cAMP = adenosine 3, 5 -cyclic monophosphate. 

Methyl-3-phenyl-5-(3-trifluoromethylphenyl)-4-pyridone. See l-Methyl-O-phenyl-S-fO-ltrifluoromethyl) phenyl]-4(1H)-pyridinone Methyl phosphate. See trimethyl phosphate Methyl phosphite. See Trimethyl phosphite Methyl phosphonate. See Dimethyl hydrogen phosphite... 

Siloxanes and silicones, dimethyl, 3-hydroxypropylmethyl, ethers with PEG dihydrogen phosphate, compds. with N-[3-(dimethylamino) propyl] tetradecanamide. See Myristamidopropyl dimethylamine dimethicone copolyol phosphate Siloxanes and silicones, dimethyl, 3-hydroxypropyl methyl, ethers with polyethylene glycol acetate. See Dimethyl, methyl (polyethylene oxide acetate-capped) siloxane... 

Dimethyl, methyl (polyethylene oxide acetate-capped) siloxane Disodium lauriminodipropionate Polysorbate 80 antistat, textile finishes Cetrimonium chloride Polyglyceryl-10 tetraoleate Stearyl hydroxyethyl imidazoline antistat, textile finishing Guanidine hydrochloride Quaternium-27 antistat, textile lubricants PEG-3 dioctoate PEG-2 oleate TEA-phosphate antistat, textile maintenance Quaternium-27 antistat, textile processing PEG castor oil antistat, textile scours Oleth-4 phosphate antistat, textile softeners Lauramine oxide antistat, textile spin finishes Alkyl trimethyl ammonium chloride Ceteareth Cetethyl morpholinium ethosulfate Cetoleth Cetrimonium bromide Lauramine oxide PEG cocamine PEG-2 oleamine PEG oleate PEG stearamine PEG stearate Polyethylene wax Polysorbate 60 Sodium cocoamphoacetate Trideceth phosphate... 

The hydrolysis of dimethyl acetoin phosphate at pH 7.7-8.2 is extremely fast (120), whereas the hydrolysis of methyl acetoin methylphosphonate (121) is 200 times slower. Empirically it can be assumed that the P(V) atom of phosphates is harder than the phosphonates and, accordingly, the phosphates react faster with hard bases. 

Organophosphorus reagents that inhibit hydrolases (serine hydrolases) diethyl p-nitrophenyl phosphate (paraoxon) diisopropyl phosphofluoridate (DFP) dimethyl(dichlorovinyl) phosphate (dichlovos) O -methylphosphoramidothioate 3-hydroxy-N-methyl-cis-crotonamide dimethylphosphate tetraethyl pyrophosphate (TEPP)... 

Synonyms Apavinphos 2-Butenoic acid 3-((dimethoxyphosphinyl)oxy)methyl ester 2-Carbomethoxy-l-methylvinyl dimethyl phosphate a-Carbomethoxy-l-methylvinyl dimethyl phosphate 2-Carbomethoxy-l-propen-2-yl dimethyl phosphate CMDP Compound 2046 3-((Dimethoxyphosphinyl)oxy)-2-butenoic acid methyl ester 0,0-Dimethyl-0-(2-carbomethoxy-1 -methylvinyl)phosphate Dimethyl-1 -carbomethoxy-1 -propen-2-yl phosphate (9,0-Dimethyl 1-carbomethoxy-l-propen-2-yl phosphate Dimethyl 2-methox-ycarbonyl-l-methylvinyl phosphate Dimethyl methoxycarbonylpropenyl phosphate Dimethyl (l-methoxycarboxypropen-2-yl)phosphate 0,0-Dimethyl 0-(l-methyl-2-carbox-yvinyl)phosphate Dimethyl phosphate of methyl-3-hydroxy-c/5 -crotonate Duraphos ENT 22324 Fosdrin Gesfid Gestid 3-Hydroxycrotonic acid methyl ester dimethyl phosphate Meniphos Menite 2-Methoxycarbonyl-l-methylvinyl dimethyl phosphate c/5 -2-Methoxycarbonyl-l-methylvinyl dimethyl phosphate l-Methoxycarbonyl-l-propen-2-yl dimethyl phosphate Methyl 3-(dimethoxyphosphinyloxy)crotonate NA 2783 OS 2046 PD 5 Phosdrin c/.s-Phosdrin Phosfene Phosphoric acid (l-methoxycarboxypropen-2-yl) dimethyl ester. 

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