Cetrimonium chloride

Cetrimonium chloride is used in hair conditioners, fabric softeners, and antistatic agents for hair and fibers. It makes fabrics and hair less prone to static electricity buildup by making them slightly conductive. 

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Quaternary ammonium compounds are cationic surfactants that bind well to anionic surfaces like the protein in hair. The ammonium end sticks to the hair, leaving the long fatty end of the molecule to act as a lubricant. They are slightly conductive, so they reduce the buildup of static electricity. Quats, as they are sometimes called, include compounds like stearalkonium chloride, disteardimonium chloride, quaternium-5, or quaternium-18, polyquaternium-10 and they are all similar in form and function to cetrimonium chloride. These compounds are also widely used as fabric softeners, for all of the same reasons they make good hair conditioners. They are also used to thicken the shampoo. 

This preservative has been used in a dry eye treatment and was shown in a clinical study to have the same biocompatibility as another marketed preparation [152]. Cetrimonium chloride (0.01%) produced the same corneal and conjunctival changes after one-month ocular administration in rats as the effective levels of other major preservatives [153],... 

CONDITIONER BASE (HAIR) - Water (Aqua), Cetrimonium chloride (palm oil based conditioning agent) Cetearyl alcohol (coconut based wax), Brassica napus Canola ... 

Examples of commonly used quats are stearalkonium chloride, cetrimonium chloride, and dicetyldimonium chloride ... 

CH3(CH2)l6CH2-N+(CH3)2(C6H5CH2)Cl-Stearalkonium chloride CH3(CH2)i4CH2-N+(CH3)3Cl-Cetrimonium chloride CH3(CH2)l4CH2]2-N+(CH3)2Cl-Dicetyldimonium chloride... 

Verboom el al. (Alberto-Culver) Cetrimonium chloride/stearalkonium chloride = 0.65-2.0 <1% total amount of cetrimonium chloride + stearalkonium chloride Synergistic effect rinse-off or leave-in conditioner provides silk wet feel and inhibits flyaway at 34% RH... 

KrimdOO. (Fabriquimica] Cetearyl alcohol, cetrimonium chloride. 

Creme rinses and most hair conditioners are basically compositions containing cationic surfactant in combination with long chain fatty alcohol or other lipid components. Distearyldimonium chloride, cetrimonium chloride, stearalkonium chloride, and behentrimonium methosulfate are typical cationic surfactants used in many of today s hair conditioning products. Amines like dimethyl stearamine or stearamidopropyl dimethylamine are other functional cationics used in these products. Cationic polymers such as Polyquaternium-10 (quaternized ceUulosic) and Polyquatemium-7 (copolymer of diallyl dimethyl ammonium chloride and acrylamide) are also used (more in shampoos than in hair conditioners) however, care must be taken to avoid buildup on hair when formulating with cationic polymers. See the section on Cationic Polymers and Their Interactions with Hair in Chapter 7. 

Neutral lipids are found in many different types of hair products including some conditioners, pomades, and men s hair dressings. Monofunctional cationic ingredients such as stearalkonium chloride and cetrimonium chloride are the primary active ingredients of creme rinses and other hairconditioning products, and the increased usage of these products, over the last decade, makes this soil type even more common. 

Robbins et al. [29] have shown that washing monofunctional cationic surfactants like cetrimonium chloride from hair with normal alkyl sulfates or alcohol ether sulfates does not remove all the cationic from the hair, and, in addition, the anionic detergent can build up with the cationic. Adsorption complexes formed in this manner adsorb to hair with the potential for building up. However, this type of buildup generally levels after five to six treatments. Shorter chain-length surfactants like deceth-2 or -3 ether sulfate do not build up in the same manner. In addition, hair matting has been reported in vivo and attributed to the adsorption of cetrimonium bromide on hair [42]. 

Creme rinses are analogous to conditioning shampoos in causing hair effects chiefly by the adsorption of ingredients to hair. The primary active ingredient of most creme rinses is a cationic surfactant such as stearalko-nium chloride or cetrimonium chloride. 

Figure 6-2. Illustration of ring dyeing. Cross sections of hair fibers treated with cetrimonium chloride for 1 h and then stained with Rubine dye after sectioning. The staining shows where the cationic surfactant had penetrated into the hair.

Temporary hair dye products frequently contain thickeners, a surfactant, sometimes a hair-setting polymer, and a buffer or acid such as tartaric, acetic, or citric to provide an acid medium for application of the dyes to the hair. To make the hair rinses described in Table 6-11, first hydrate the hydroxyethylcellulose (0.7 g) with 49 g of water by stirring, then add the neodol and the nonoxynol. Add the remaining water followed by the buffer, and then slowly dissolve the dyes in the product with stirring. Finally, add the cetrimonium chloride and stir until it is completely dissolved. 

Chem. Descrip. Amodimethicone, trideceth-12, and cetrimonium chloride... 

Cetyl trimethyl ammonium chloride. See Cetrimonium chloride... 

Hexadecyl palmitate. See Cetyl palmitate Hexadecyl sodium sulfate. See Sodium cetyl sulfate Hexadecyl trimethyl ammonium chloride. See Cetrimonium chloride Hexaetlr ene glycol. See PEG-6... 

Abiumine TMC. See Cetrimonium chloride Abiumine TMS. See Steartrimonium chloride Abiumoi BS. See Butyl stearate Abiumoi PSS. See Phenol, styrenated Abiumox C-7. See PEG-7 cocamine Abiumox CAPO. See Cocamidopropylamine oxide... 

See Cetrimonium chloride AMMONYX CO. See Palmitamine oxide AMMONYX D34 AMMONYX D34PPG. See Dicetyidimonium chloride AMMONYX DMCD-40. See Lauramine oxide AMMONYX DO. See Decylamine oxide AMMONYX GA-70PG, AMMONYX GA-90. See Dipalmitoylethyl hydroxyethylmonium methosulfate... 

Arquad 12-37W. See Laurtrimonium chloride Arquad 16-25LO, Arquad 16-25W, Arquad 16-29, Arquad 16-29W. See Cetrimonium chloride... 

Barquat BR CB-50, Barqual BR DM-50, Barquat CB-50, Barquat CB-80. See Benzalkonium chloride Barquat CME-35, Barqual CME-A. See Cetethyl morpholinium ethosulfate Barquat CT-29. See Cetrimonium chloride Barquat DM-50, Barquat DM-80, Barquat MB-50, Barquat MB-80. See Benzalkonium chloride... 

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