Dimethyl hydrogen phosphate

Slowly hydrolyzes in water and in acidic media but is more rapidly hydrolyzed under alkaline conditions to dimethyl hydrogen phosphate and dichloroacetaldehyde (Capel et al., 1988 Hartley and Kidd, 1987 Worthing and Hance, 1991). In the Rhine River (pH 7.4), the hydrolysis half-life of dichlorvos was 6 h (Capel et al, 1988). 

Dimethylethyl) -3- (methylthio) -1,2,4 -triazin-5 - (4 H) -one, see Metribuzin 7V,7V-Dimethylformamide, see Dimethylamine Dimethyl hydrogen phosphate, see Dichlorvos TV.O-Dimethylhydroxylamine, see Linuron 0,0-Dimethyl 5- (TV-hydroxymethylcarbamoyhnethyl) phosphorothioate, see Dimethoate 0,0-Dimethyl 5- (TV-hydroxymethylcarbamoyhnethyl) phosphorothiolate), see Dimethoate 0,0-Dimethyl 5- (A-methylcarbamoylmethyl) phosphorothiolate, see Dimethoate O, O-Dimethyl-0- (4- (methylthio) -m-tolyl) phosphate. 

In humans and animals, the absorption, distribution, and excretion of trichlorfon is rapid. The biological half-life of trichlorfon in mammalian blood is estimated to be 30 min. It eliminates from the blood stream within a matter of 1.5 h, and only low levels are detected after 8-24 h. In mice, 70-80% of an oral dose of trichlorfon gets excreted within the first 12 h. Trichlorfon undergoes transformation via dehydrochlorination to form dichlorvos in all biological fluids and tissues. The major metabolites of trichlorfon found in vivo are demethyl trichlorfon, demethyl dichlorvos, dimethyl hydrogen phosphate, methyl hydrogen phosphate, phosphoric acid, and trichloroethanol. The excretion of trichlorfon and its metabolites occurs primarily via the urine. 

FIGURE 6.1 Exposure-response of a sensor based on functional luminescent prepolymeric complexes to increasing concentrations of dimethyl hydrogen phosphate (DMHP), dichlor-vos, phosdrin, and dicrotophos, with best-6t curves shown. 

Dimethyl hydrogen phosphate Dimethyl hydrogen phosphite 1,2-Dimethyl-1 //-imidazole... 

Dimethyl hydrogen phosphate 0,0-Dimethyl hydrogen phosphate. See Dimethyl phosphate Dimethyl hydrogen phosphite CAS 868-85-9 EINECS/ELINCS 212-783-8 UN 1993... 

Dimethyl hydrogen phosphate Dimethyl phosphate CjHAP 813-78-5 126.048 174 dec 1.3225 1.408 vs H2O, ace, EtOH... 

Zakharkin, L. I. Guseva, V. V. Ol shevskaya, V. A. 2001. Synthesis of dimethyl (m-carboran-9-yl)phos-phonate and dimethyl (p-carboranyl)phosphonate by palladium-catalyzed cross-coupling of 9-I-m- and 2-I-p-carboranes with dimethyl hydrogen phosphate. Russ. J. Gen. Chem. 71 903-904. 

Further studies on 1,3-dipolar addition reactions of diazophosphonates have been recorded,122 and work on 2-diazo-l-hydroxyalkylphosphonates also continues.123 The ester (155 R = H) reacts with esters of acetylenedicarboxylic acid without liberation of nitrogen to give stereoisomeric C-phosphorylated pyrazolines, which can be decomposed with both phosphorus-carbon and carbon-carbon bond fission, affording mixtures containing dimethyl acetylphosphonate, dimethyl hydrogen phosphonate, and tri(alkoxycarbonyl)pyrazolines. In the reaction between the same diazophosphonate and diazomethane, the latter conceivably acts as a basic catalyst for proton transfer in a series of steps which includes phosphonate-phosphate isomerization. The importance of a labile proton is demonstrated by the fact that the ester (155 R = Me) does not react in the manner described above. 

When a solution of the ester (155 R = H) in dioxan is warmed at 80 °C, the phosphonate (156) is produced together with about 5% yields of each of dimethyl hydrogen phosphonate and diazoacetoacetic ester (Scheme 8) the enol phosphate (157) could not be detected. The explanation for this sequence of reactions also relies on proton mobility, and the reaction is known to be acid-catalysed.124... 

Problem 13.58 Inorganic acids such as HjSO , H,PO, and HOCI (hypochlorous acid) form esters. Write structural formulas for (a) dimethyl sulfate, (b) tribenzyl phosphate, (e) diphenyl hydrogen phosphate, (d) /-butyl nitrite, (e) lauryl hydrogen sulfate (lauryl alcohol is n-CuH jCH OH), (/) sodium lauryl sulfate. ... 

Octahedral and tetrahedral solvates (A1S )(C104)3 [n = 4,6 S = trimethyl phosphate (TMPA), hexamethylphosphorotriamide (HMPT), triethyl phosphate (TEPA), dimethyl methylphosphonate (DMMP), diethyl ethylphosphonate (DEEP), and dimethyl hydrogen phosphite (DMHP)] are shown by Al NMR to have tetrahedral and octahedral structures which are retained in nitromethane solution. 

When performed in ether at —70 °C containing HCl, the reaction between triethyl phosphite and either chloral or bromoacetone affords higher yields of the a-hydroxyphosphonates (34), relative to vinyl phosphate, than are normally obtained. The rate-determining step in the formation of the phosphonate (35) from chloroacetone and dimethyl hydrogen phosphonate appears to be the tautomerism of dialkyl phosphonate to phosphite. ... 

See Sodium phosphate dibasic dihydrate Aibrite DMHP. See Dimethyl hydrogen phosphite... 

Methyl-3-phenyl-5-(3-trifluoromethylphenyl)-4-pyridone. See l-Methyl-O-phenyl-S-fO-ltrifluoromethyl) phenyl]-4(1H)-pyridinone Methyl phosphate. See trimethyl phosphate Methyl phosphite. See Trimethyl phosphite Methyl phosphonate. See Dimethyl hydrogen phosphite... 

Synonyms Siloxanes and silicones, dimethyl-, 3-hydroxypropylmethyl, ethers with polyethylene glycol 3-[dimethyl [3-[(oxotetradecyl) amino] propyl] ammonio]-2-hydroxypropyl hydrogen phosphate, hydroxides, inner salts, chloride Classification Polymeric quaternary ammonium salt... 

---