Diethylamino

DCIA is 7-diethylamino-3-[(4 -(iodoacetyl)amino)phenyl]-4-methylcoumarin, a derivative of the basic aminomethylcoumarin structure that contains a sulfhydryl-reactive iodoacetyl group and a diethyl substitution on its amine. This particular coumarin derivative is among the most fluorescent UV-excitable iodoacetamide probes available (Sippel, 1981) (Invitrogen). 

Carboxylic acids 7-(Diethylamino)-3-[4- ((iodoacetyl)amino)phenyl]-4-methylcoumarin 68... 

The comparison of three coumarin compounds, 4-(bromomethyl)-7-methoxy-coumarin (Br-MMC), 7-(diethylamino)coumarin-3-carbohydrazide (DCCH), and 7-(diethylamino)-3-[(4-(iodoacetyl)amino)phenyl]-4-methylcoumarin(DCIA) as potential chemiluminescence with HPLC was reported by Grayeshi and Vasto (35) (see Chemical Structure 2). 

The two reactnts initially in diethyl ether at ambient temp.during Ih followed by evapn. of solvent and reflusing of the residual material (6h) in aqueuous ethanol to give 7-diethylamino-3-cyanocoumarin. 

Sample Preparation. Photohardenable formulations based on TMPTA in combination with other reagents including photoinitiators (Quanticure ITX or 7-diethylamino-3-cinnamoyl coumarin, depending on the specific experiment) and colorless dye precursors developable upon contact with acidic resin coated paper were used as a test composition. 

Still another example is an initiating system composed of 7-diethylamino-3 -(2 -N-methyl-benzimidazolyl)-coumarin and diphenyliodonium hexafluorophosphate. This composition initiates the polymerization of methyl methacrylate in visible light. After the dye absorbs flic light energy, quick electron transfer takes place from the dye to the iodonium salt to produce free radicals. " The light induced reaction is claimed to occur mainly through the excited singlet state of the coumarin and results in low sensitive to O2. The fluorescence of the coumarin compound was reported to be quenched efficiently by the iodonium salt. " The reaction was observed to be in accord with the Stem-Volmer equation. The influence of the concentration of coumarin on the polymerization rate of methyl methacrylate led to the conclusion that the free radicals from coumarin act mainly as chain terminators. ... 

Fouaissier and Chesneau reported that an cosine dye and ketocoumarin in the presence of an amine, acetone and iodonium salts initiate photocuring with light greater in wave length that 400 nm., The ketocoumarin (7-diethylamino-3,3 -oxydo-2H-chromen-2-one) was found by them to be a very useful additive to photo curable formulations, either in free-radical or in ionic curing processes illustrated as follows... 

Raju, B. B. and Varadarajan, T. S. 1995. Photophysical properties and energy transfer dye laser characteristics of 7-diethylamino-3-heteroaryl coumarin in solution. Laser Ghent. 16(2) 109-120. 

Pre-column fluorimetric derivatization of adenosine and its cyclic monophosphate with chloroacetaldehyde, and pre-column chemiluminescence derivatization of 5-fluoropyrimidines with 7-diethylamino-3-(4-iodoacetamidophenyl)-4-methylcoumarin, have yielded derivatives suitable for reversed-phase h.p.I.c. analysis. 

Diethylamino)-3- 4-maleimidylpheny[)-4-methylcoumarin. -[4- 7-Diethylamino-4-methylcoumarin-3-yl)phenyl maleimide. CPM [76877-33-3]... 

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