8- Amino-7-diethylamino

Brilliant cresyl Amino-diethylamino-methyl Red- Blue 0-0-10... 

However, prior protective acetylation of the amino group leads to a good yield of the 5-nitro compound [2-acetamido-4-methyl-5-nitroselenazole, m.p. 185 C (19)j. Similarly. 2-diethylamino-4-methy)-selenazole with nitric acid gives the. 5-nitro derivative [vellow needles, m.p. 93°C (26)],... 

Coumarin, 7-amino-7-(diethylamino)-, I, 333 Coumarin, 7-amino-4-methyl-fluorescence spectra, 3, 601 Coumarin, 7-amino-3-phenyl-brightening agents, I, 339 Coumarin, 4-aryl-occurrence, 3, 677 synthesis, 3, 810 Coumarin, 3-arylazo-4-hydroxy-structure, 3, 643 Coumarin, 3-bromo-reactions... 

The enamino ketone (49) was reported to give no identifiable products on reaction with N,N-dimethyl carbamoyl chloride 63). However, reaction of (49) with N,N-diethyl carbamoyl chloride in refluxing chlorobenzene gave the N-(3-diethyl-amino-5,5-dimethylcyclohex-2-en-1 -ylidene)pyrrolidinium salt, isolated as the perchlorate. The latter must have been formed as outlined in Scheme I, involving initial O carbamoylation followed by an addition-elimination reaction to give 138 cation which can react with diethylamino anion by a further addition-elimination displacement to give the product 46). 

The quaternization of pyrazine compounds has not been extensively studied, and, therefore, a detailed discussion of the effect of substituents is not possible. Recently Cheeseman has shown, from spectroscopic evidence, that 2-amino- and 2-diethylamino-pyrazine (50, Y = NH2 and NEt2) quatemize at N-4, although protonation occurs at position-1. Other substituted pyrazines from which quaternary salts of structure 51 are formed include 2-chloro- and 2-... 

Treatment of ethyl 4-chloro-7-diethylamino-6-nitro-l,8-naphthyridine 3-carboxylate (104) with the amines RH [R = N(CH2)s NH(CH2)N(C2Hs)2] gives the corresponding 4-amino derivatives [105, R = N(CH2)s, 74% and 105, R = NH(CH2)N(C2Hs)2, 50%]. With diethylamine the 7-chloro-6-nitro derivative of nalidixic acid (i.e., 106) yields the 7-diethylamino compound 107 (62%) (79YZ155). 

The 2-amino-selenazoles are crystalline compounds, and sometimes unstable, for example, the parent compound on heating in water undergoes complete decomposition. A few of these selenazoles which are substituted in the amino group are oily liquids. The basic character is more pronounced than in the alkyl- and aryl-selenazoles. The hydrochloride salts are, therefore, not so easily hydrolyzed in aqueous solution. 2-Amino- and 2-methylamino-4-methylselenazole have been considered to exist partly in the tautomeric selenazol-2-one imine form from comparison of their ultraviolet spectrum with that of 2-diethylamino-4-methylselenazole. ... 

Chamical Nama 4-[(7-Chloro-4-quinolinyl)amino] -2-[(diethylamino)-methyl] phenol Common Nama 4-(3 -diethylaminomethyl-4 -hydroxyanilino)-7[Pg.75]

Chemical Name 4-amino-3-butbxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride Common Name Oxybuprocaine... 

The addition of 2-propenyltris(diethylamino)titanium to 2-(dibenzylamino)alkanals, readily prepared from amino acids, yields the anti-amino alcohols with high stereoselectivity and free of racemization91. Allylsilanes, with Lewis acids under the conditions of chelation control, lead to the iyn-diastereomers91. 

CN a-[[2-(diethylamino)ethyl]amino]benzeneacetic acid 3-methylbutyl ester... 

RN 364-62-5 MF C,4H22C1N302 MW 299.80 EINECS 206-662-9 CN 4-amino-5-chloro-A-[2-(diethylamino)ethyl]-2-methoxybenzamide... 

CN 4-amino-2-propoxybenzoic acid 2-(diethylamino)ethyI ester monohydrochloride... 

RN 3686-58-6 MF C15H22N2O3 MW 278.35 EINECS 222-976-9 CN 2-[[(diethylamino)acetyl]amino]-3-methylbenzoic acid methyl ester... 

Some benzofluorans having two amino groups also develop blue color. These include 9 -ethylamino-4 -(methoxycarbonylmethylamino)benzo[a]-fluoran (38),32 9 -diethylamino-4 -a-naphthylmethylaminobenzo [ajfluoran... 

Introduction of an additional substituent such as alkyl, alkoxy, halogen, etc. at 3 -position has a large effect on color. That is, green color changes to red color when there is a tertiary amino group at 2 -position. Thus, 2 -dibenzylamino-6 -diethylamino-3 -methylfluoran (47 R1 = H, R2 = CH3 ),40 2 -dibenzylamino-6 -diethylamino-3 -ethylfluoran (47 R1 = H, R2 = C2H 5),34 3 -chloro-2 -dibenzylamino-6 -diethylaminofluoran (47 R1 = H, R2 = Cl),34 6 -((V-ethyl-4-methylanilino)-3 -methyl-2 -((V-methylanilino)flu-... 

Replacement of amino groups at 2 -position with azomethine groups gives brown color. These include 6 -diethylamino-2 -ethylidenamino-fluoran (49 R = CH3),42 2 -(2-butenylidenamino)-6 -diethylaminofluoran (49 R = CH3CH=CH),42 2 -benzylidenamino-6 -diethylaminofluoran (49 R = CsHs),42 and 2 -cinnamylidenamino-6 -diethylaminofluoran (49 R = C6H5CH=CH).42... 

Table 2 shows melting points of representative examples of the keto acids (66) having a tertiary amino group at 4-position. 2-(4-Diethylamino-2-hydroxybenzoyl)benzoic acid (66b) is the most popular among the keto acids. 

Preparation of 2 -Amino-6 -diethylaminofluoran (74a). A mixture of 2-(4-diethylamino-2-hydroxybenzoyl)benzoic acid (0.1 mol), p-anisidine (0.1 mol), and concentrated sulfuric acid (100 g) was stirred at 50 °C for 24 h. After being cooled, the mixture was poured into water (500 ml), and made alkaline by 20% aqueous sodium hydroxide. The precipitate was filtered off, washed with water, dried, and then recrystallized from toluene to give 2 -amino-6 -diethylaminofluoran in 90% yield as an off-white powder, mp 213-215 °C. 

Chloro-5,8-dimethoxy-3-methylquinoxaline (86) gave 2-[(4-diethylamino-l-methylbutyl)amino]-5,8-dimethoxy-3-methylquinoxaline (87) (H2NCHMeCH2 CH2CH2NEt2, K2C03, 98°C, 8 h 10%)690... 

C19H31N207+ C1- H20 2-(Diethylamino)ethyl 4-(/ -D-glucopyranosyl-amino)benzoate, monohydrate (N-/ -D-glucopyranosylprocaine, monohydrate) (PRCGLS)104... 

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