1.2- dibutyl

In addition to dehydration with phenyl isocyanate, ethyl nitroacetate has been reported to behave on thermolysis (refluxing mesitylene) as a source of flilminic acid, trapped with -dec-5-ene to afford fra/w-4,5-dibutyl-2-isoxazoline [41]. 

The conversion of primary alcohols and aldehydes into carboxylic acids is generally possible with all strong oxidants. Silver(II) oxide in THF/water is particularly useful as a neutral oxidant (E.J. Corey, 1968 A). The direct conversion of primary alcohols into carboxylic esters is achieved with MnOj in the presence of hydrogen cyanide and alcohols (E.J. Corey, 1968 A,D). The remarkably smooth oxidation of ethers to esters by ruthenium tetroxide has been employed quite often (D.G. Lee, 1973). Dibutyl ether affords butyl butanoate, and tetra-hydrofuran yields butyrolactone almost quantitatively. More complex educts also give acceptable yields (M.E. Wolff, 1963). 

Because they are widely used as solvents many simple dialkyl ethers are commercially available Diethyl ether and dibutyl ether for example are prepared by acid catalyzed condensation of the corresponding alcohols as described earlier m Section 15 7... 

According to this disconnection the butyl group is derived from lithium dibutyl cuprate A suitable preparation is... 

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