Diabetes mellitus, type

QURESHI A A, SAEED A s, FAROOQ A K (2002) Effects of Stabilized rice bran, its soluble and fiber fractions on blood glucose levels and serum lipid parameters in humans with diabetes mellitus Types 1 2. J Nutri Biochem, 13 175-87. 

Mr Patel came to the UK from his native India in 1969 when he was 22 years old. For almost 30 years he has run, very successfully with the help of his family, a small business which now employs 30 people in the suburbs of Leicester. At the age of 38 years, Mr Patel was diagnosed with diabetes mellitus (Type 1 diabetes) and now has trouble controlling his weight and is on medication to regulate his plasma triglyceride and cholesterol concentrations. 

Diabetes mellitus (type 1) proteinuria ACE inhibitors Heart failure ACE inhibitors Diuretics... 

Julie Singer is a 55-year-old white woman who was admitted to the emergency department in acute distress. A previous physical examination showed hypertension and diabetes mellitus type 2. The patient s present medications include enalapril 40 mg, nifedipine 60 mg, and 100 U insulin. A physical examination revealed prominent ankle edema, a palpable spleen, and hepatomegaly. Chest radiography revealed diffuse cardiac enlargement and left ventricular hypertrophy. Based upon the history and clinical hndings, what is your diagnosis and what treatment do you recommend ... 

The other type of diabetes mellitus, type II, is far more common. In contrast, type II is not an autoimmune process and may or may not be insulin dependent that is, a diabetic state that is most effectively managed by insulin therapy. Frequently, NIDDM is used interchange-... 

Hypoglycaemic and hyperinsulinemic effects of some Egyptian herbs used for the treatment of diabetes mellitus (type II) in rats. Egypt J Pharm Sci 1995 36(1-6) 331-342. 

It is indicated in non-insulin dependent diabetes mellitus (type II, maturityonset diabetes) whenever treatment by diet alone proves to be inadequate. 

Adjunct to diet to lower blood glucose in patients with non-insulin-dependent diabetes mellitus (Type II) whose hyperglycemia cannot be controlled by diet alone... 

T Diabetes mellitus, caused by a deficiency in the secretion or action of insulin, is a relatively common disease nearly 6% of the United States population shows some degree of abnormality in glucose metabolism that is indicative of diabetes or a tendency toward the condition. There are two major clinical classes of diabetes mellitus type I diabetes, or insulin-dependent diabetes mellitus (IDDM), and type II diabetes, or non-insulin-dependent diabetes mellitus (NIDDM), also called insulin-resistant diabetes. 

There are two types of diabetes mellitus — type I, or insulin-dependent diabetes mellitus, and type II, or noninsulin-dependent diabetes mellitus. 

For the first time in history there was clear, unambiguous clinical evidence, in humans, that symptoms of diabetes mellitus could be controlled with the exogenous administration of the active factor of the pancreas—insulin. Thus, replacement therapy with the newly discovered hormone, insulin, had arrested what was clearly an otherwise fatal metabolic disorder. From that point forward, diabetes mellitus (type 1) became a manageable disease by pharmacological intervention. 

HLA (human leukocyte antigen) DR2 is strongly positively correlated with SLE and multiple sclerosis, and negatively correlated with diabetes mellitus type 1. HLA DR3 is correlated strongly with Sjogren s syndrome, myasthenia gravis, SLE and diabetes mellitus type 1. HLA DR4 is correlated with the genesis of rheumatoid arthritis and diabetes mellitus type 1. 

Rosiglitazone 9, an agonist of peroxisome proliferator activated receptor-y (PPARy), is a recently introduced antihyperglycemic thiazolidinedione effective in the treatment of noninsulin dependant diabetes mellitus (type II diabetes). A seven-step synthesis was developed (Scheme 3), which utilised supported reagents in combination with in-line SPE purifications. The introduction of the pyridine moiety provided a convenient molecular handle by which to purify the molecule throughout the synthesis. Notably, the overall yield (46%) for this synthesis was higher than the yield reported in the initial shorter solution-phase synthesis (31%). ... 

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