Dermatosis

Haider RM, Grimes PE, McLauren C, Kress MA, Kenney JA Jr (1983) Incidence of common dermatoses in a predominantly black dermatologic practice. Cutis 32 388-390... 

Occupations associated with heavy sun exposure Inflammatory dermatoses in the area of the peels Eczema Urticaria... 

Medium-potency products are used in moderate inflammatory dermatoses. They may be used on the face and intertriginous areas for a limited time. 

Fluorouracil (5-FU) is an antineoplastic agent that usually arrests tumor cells at the Gl-S phase of the cell cycle and the choice in the treatment of carcinoma of colon or rectum it is also used in the treatment of precancerous dermatoses, especially actinic keratosis for which... 

Birmingham DJ. 1988. Contact dermatitis and related dermatoses associated with petroleum recovery and use. Occupational Medicine State of the Art Reviews 3(3) 511-523. 

Jee SH, Wang JD, Sun CC, et al. 1985. Prevalence of probable kerosene dermatoses among ball-bearing factory workers. Scand J Work Environ Health 12(l) 61-65. 

The stratum corneum plays a critical role in determining cutaneous permeability. Absorption is faster through skin that is abraded or inflamed. Chemicals that are not normally considered hazardous may be dangerous to individuals suffering from active inflammatory dermatoses. 

Worobeck SM, DiBeneditto JP Perspectives on occupational dermatoses. In Drill VA, Lazar P eds. Cutaneous Toxicity, pp 253. New York, Raven Press, 1984... 

Calcium gluconate - To decrease capillary permeability in allergic conditions, nonthrombocytopenic purpura and exudative dermatoses such as dermatitis herpetiformis for pruritus of eruptions caused by certain drugs in hyperkalemia, calcium gluconate may aid in antagonizing the cardiac toxicity, provided the patient is not receiving digitalis therapy. 

Nausea vomiting dry mouth nervousness vertigo headache drowsiness mental confusion (especially in the elderly patient) hyperpyrexia blurred vision increased ocular tension disturbance in eye accommodation urticaria and other dermatoses dysuria tachycardia palpitations eosinophilia leukopenia. 

Manifestations of chronic intoxication Severe dermatoses, marked insomnia, irritability, hyperactivity, and personality changes have occurred. Disorganization of thoughts, poor concentration, visual hallucinations, and compulsive behavior often occur. The most severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from paranoid schizophrenia. This is rare with oral amphetamines. 

Adverse reactions may include bone marrow depression with aplastic anemia agranulocytosis or thrombocytopenia (long-term therapy) peripheral neuritis purpura myopathy loss of hair reversible azoospermia dermatoses hypersensitivity vomiting diarrhea abdominal pain nausea elevated alkaline phosphatase and AST. 

Management of pruritus caused by allergic conditions such as chronic urticaria, atopic and contact dermatoses and in histamine-mediated pruritus. 

Concomitant conditions Use with caution in the following patients exposed to extreme heat or phosphorus insecticides atropine or related drugs because of additive anticholinergic effects those in a state of alcohol withdrawal those with dermatoses or other allergic reactions to phenothiazine derivatives because of the possibility of cross-sensitivity those who have exhibited idiosyncrasy to other centrally acting drugs. 

Pruritus Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses Contact dermatitis, atopic dermatitis, nummular eczema, stasis eczema, asteatotic eczema, lichen planus, lichen simplex chronicus, insect and arthropod bite reactions, first- and second-degree localized burns, and sunburns. 

Riboflavin (vitamin B2) is found in liver, milk, meat, green vegetables, cereals and mushrooms. It is active in the form of two coenzymes, flavin mononucleotide and flavin adenine dinucleotide. As a coenzyme for proton transfer in the respiratory chain it is indispensable for energy-release from carbohydrates, lipids and proteins. Riboflavin deficiency only occurs in combination with deficiencies of other members of the vitamin B family. The symptoms of such deficiency consist of angular stomatitis, lesions of the cornea, dermatoses and normochromic normocytic anaemia. 

Juhlin L, Johansson GO, Beimich H, et al. Immunoglobulin E in dermatoses. Arch Dermatol 100 12-16. 

Topical corticosteroids are most useful in inflammatory dermatoses, such as eczematous dermatitis and psoriasis they may also be helpful in other skin diseases that have a prominent inflammatory component, such as autoimmune blistering diseases (e.g., bullous pemphigoid and pemphigus vulgaris) and lupus erythematosus. 

Minocycline is frequently used in the treatment of chronic facial dermatoses. Increased usage has resulted in local skin pigmentation, particularly at sites of previous tissue trauma that is unrelated to the photosensitization phenomenon characteristic of this class of drug. This effect does not appear to be dose dependent and usually resolves in months to years following drug discontinuation. 

Relief of inflamed and pruritic dermatoses Topical 1 -3 times a day. Foam Apply twice a day. 

Dermatoses Topical (Cream) Apply sparingly 2-4 times/day. (Ointment) Apply sparingly 1- 3 times/day. 

Dermatoses, corticosteroid-unresponsive Topical Apply 1-2 times/day. Maximum 50gfor2wk,... 

Relief of inflammation or pruritus associated with corticoid-responsive dermatoses ... 

It is antihistaminic agent having antiemetic, sedative, anticholinergic and local anaesthetic property. Used in anxiety, pruritus and dermatoses as an adjunct therapy in acute/ chronic alcoholism. 

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