CORE study

Berner, W., Oeschger, H. and Stauffer, B. (1980). Information on the CO2 cycle from ice core studies. Radiocarbon 22,227-235. 

Other experiments are planned to study the location, distribution and resuscitation of ultramicrobacteria in large three-dimensional sandpacks. Such studies will allow a more realistic approximation of reservoir conditions than the unidirectional core studies. We do not consider that the ultramicrobacteria will reach or grow in areas where residual oil is located. Selective plugging involves blocking the high permeability zones already drained of oil. We consider that the injection of ultramicrobacteria will be carried, like waterflood operations, to the areas of the strata already drained of oil and permit them to disperse through pore spaces and resuscitate in these areas. 

Siris ES, Harris ST, Eastell R, Zanchetta J, Goemaere S, Diez-Perez A et al (2004) Effect of raloxifene on the risk of nonvertebral fractures after 8 years results from the Continuous Outcomes Relevant to Evista (CORE) study. J Bone Miner Res 19(Suppl 1) F428... 

The most commonly observed side effect in patients taking raloxifene or tamoxifen was hot flashes (Agnusdei 1999 Muchmore 2000 Miller 2002). In the study by Mounts et al. (2002) in breast cancer patients < 56 years of age, the most frequent complaints during tamoxifen treatment were hot flashes (85%) and disturbed sleep (55%), whereas in the CORE study (Martino et al. 2004) hot flashes were observed in 12.5% of the raloxifene group vs. 6.9% in the placebo group. 

Cachier H (1995) Combustion carbonaceous aerosols in the atmosphere implications for ice core studies. Ice Core Studies of Global Biogeochemical Cycles, NATO ASI Series, Springer, Berlin, pp 313-346... 

The Western Arctic Shelf-Basin Interactions (SBI) project, sponsored by the ARCSS Program and the U.S. Office of Naval Research, is investigating the Arctic marine ecosystem to improve our capacity to predict environmental change. The SBI Phase II Field Implementation Plan (2002-2006) (Grebmeier et al., 2001) focuses on three research topics in the core study area ... 

We will present the basic requirements for preparing a bimane derivatized sample for HPLC analysis ana the preparation or appropriate blanks. We will then discuss the specific methods used for the three studies presented in the results section i) phytoplankton studies ii) sediment core studies iii) sulfide metabolism studies in invertebrate-bacteria symbiosis. 

The quality of a submission depends not only on the content of the submission but the tools provided to facilitate the review process. Now more than ever, FDA reviewers are receptive to electronic review aids and the use of electronic files. Simple and relatively inexpensive approaches are available. Important issues to consider during planning include the need for electronic review aids. These are electronic tools requested by the reviewer outside the electronic submission policy. Examples of these include book-marked, searchable versions of the integrated summaries and final clinical study reports for the core studies on CD-ROM or Microsoft Word versions of summaries that reviewers can cut and paste for their reviews. Since the preparation of the review summary can often be the longest part of the review, providing these tools can be useful in significantly reducing the total review time. 

Jin, R., and Gouaux, E. (2003). Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal. Biochemistry 42, 5201-5213. 

Apparatus and Procedure. It was necessary to design more definitive tests to further evaluate the better candidate surfactants. This was accomplished by means of a multi-phase dynamic-fiow test that consists of a small packed bed through which surfactant solution can be passed followed by gas to produce in situ foam. The pressure drop through the column is measured as the fiuid is drawn through the column at a constant volumetric fiow rate. From the recorded data, relative mobilities of the liquid and gas phases may be calculated. The change in gas mobility due to the presence of the surfactant is very closely related to the effectiveness of that surfactant for mobility control in oil core studies. A schematic drawing of the apparatus is shown in Figure 2. 

Degradation rates for sediment and soil are based on inferences from sediment core studies [72],... 

Water Stable Isotopes Atmospheric Composition and Applications in Polar Ice Core Studies... 

Figure 12 Alkenone data acquired with planktonic foraminiferal can be used to remove the temperature effect from oxygen isotopic signals in order to assess global (ice volume) and regional (evaporation/precipitation balance) contributions to isotopic change. Data come from an equatorial Atlantic core studied by Schneider et al. (1996) the isotopic deconvolution was made by the present author. Note that the structure and amplitude of the temperature-corrected planktonic record are consistent with current thinking on the global ice volume signal for the late...

These relationships have been generally confirmed with down-core studies. These... 

Goto-Azuma K. and Koerner R. M. (2001) Ice core studies of anthropogenic sulfate and nitrate trends in the Arctic. J. Geophys. Res. Atmos. 106(D5), 4959-4969. 

The West-Central zone (Table 3), where the core studied by Stanton et al. (2001a) and Stanton et al. (2001b) was obtained is the only water-quality zone with a statistically significant correlation between As and pH at the 0.05 level and a Pearson correlation coefficient greater than 0.3. The correlation coefficient for the West-Central zone is 0.46, and a graph of As versus pH (Fig. 5) for the zone shows that nearly all samples with As... 

Adsorption/desorption processes also appear to affect As concentrations along flow paths in the West-Central zone of the northwest part of the basin, where the highest As concentrations typically occur for samples with pH values of 8.5 or higher. Increasing As concentrations at higher pH values is consistent with data from a core studied by Stanton et al. (2001a and b), which indicate that anion-exchangeable As is present on Fe oxides in the area. 

The atmospheric burden of anthropogenic CO2 is very well known because it has been measured since 1958 and recent ice core studies indicate how the atmospheric CO2 evolved between the pre-industrial period and 1958 (Fig. 11.3). Because industries and governments keep records of the amount of fossil fuel recovered, this number is also known. The amount of atmospheric CO2 increase over the period 1860-1989 is estimated to be only 40% of total emissions (Table 11.1). Where has the rest gone ... 

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