30 Containment systems Documentation

This directory contains the USEPA Pesticide and Industrial Chemical Risk Analysis and Hazard Assessment system. Documentation for PIRANHA is contained in a MANUALS subdirectory enter PIRANHA C where C is a hard disk to receive the output files to run the sy stem. For efficient operation of PIRANHA, transfer the files from the CD-ROM to your hard disk, (it requires 28 MB). Data files are accessed from the CD-ROM when running PIRANHA. 

This brings to mind another common problem. SOPs must be readily available in areas where GLP work is conducted. Protocols also must be accessible. Even when these documents exist only in electronic form, they must still be available, especially in the laboratory and study rooms. This means that computer systems that contain these documents must be available in the laboratory and study rooms and that all personnel who conduct work according to these SOPs must have access. The same is true for protocols and protocol changes. In cases where a merged system exists, i.e., both paper and electronic media are simultaneously in use, it is perfectly acceptable that only the electronic form is available in the laboratory areas while electronic or paper documents are available in offices. The only caveat is that a process must be in place to ensure the equivalency of the electronic and paper media. 

This section provides a summary description of what this management system document contains. Some organizations choose to place their incident investigation policy statement here. 

Computer system documents contain the following elements. 

Regular, comprehensive inspections to ensure the safe condition of site equipment is another important consideration. There must be clear lines of responsibility for inspection and maintenance of crucial containment systems. A formal system must be in place for documenting recommendations and communicating them clearly and quickly to the appropriate managers in the organization. 

This document is a detailed presentation of the approach being undertaken on the system and describes the roles and responsibihties of people involved in the work, the systems, the data to migrate, the test scripts needed, and what each test script will contain to document the process. 

On completion of installation, all documentation associated with the installation, calibration, and testing of the field instrumentation, along with any associated computerized control system documentation, should be collated by the project manager/engineer ready for IQ. Most of this documentation will be in the pre- as-built condition at this stage of the project and will, therefore, contain site (red line) markups. 

There are no standard methods for verifying microbiological integrity of container-closure systems. Documents such as that published by the Parenteral Society in 1992 ° and the PDA in 1998 may be helpful in relating microbiological integrity to secondary physical tests, but they do not specify detailed microbiological test methods. 

Accordingly, in the most recent documents, the DID is based on four principal barriers against the external release of radioactive products (fuel matrix, fuel cladding, reactor cooling circuit pressure boundary, and containment system), and on five defence levels in order to best use these barriers (illustrated in Table 9-1). 

Due to the inherent inflexibility of traditional documentation systems, documentation may be inaccurate with different versions containing inconsistent plant details. As a result, operational staff may not be well-informed about the current plant status, and different individuals may have conflicting views of the pUmt This can lead to a lack (rf awareness of potentially hazwdous developments or actions, and the consequoit development of a hazardous situation that could have beenavmded. 

The MUSE system is composed of several hundred SPARC 5 workstations, two UNDC-based NFS file servers, a UNIX-based server for the ORACLE MUSE document database (containing both document and structure data), and a number of Postscript printers, all linked through a local area network. 

Having defined and gathered data adequate for an initial reserves estimation, the next step is to look at the various options to develop the field. The objective of the feasibility study is to document various technical options, of which at least one should be economically viable. The study will contain the subsurface development options, the process design, equipment sizes, the proposed locations (e.g. offshore platforms), and the crude evacuation and export system. The cases considered will be accompanied by a cost estimate and planning schedule. Such a document gives a complete overview of all the requirements, opportunities, risks and constraints. 

GORE. The CORE Electronic Chemistry Library is a joint project of Cornell University, OCLC (On-line Computer Library Center), Bell Communications Research (Bellcore), and the American Chemical Society. The CORE database will contain the full text of American Chemical Society Journals from 1980, associated information from Chemical Abstracts Service, and selected reference texts. It will provide machine-readable text that can be searched and displayed, graphical representations of equations and figures, and full-page document images. The project will examine the performance obtained by the use of a traditional printed index as compared with a hypertext system (SUPERBOOK) and a document retrieval system (Pixlook) (6,116). 

The modern usage of P2" go Asts for the treatment of asthma dates to 1903 when the effect of injected epinephrine [51-43-4] (adrenaline) C2H23NO2, (1 R = CH3) was investigated (see Epinephrine and norepinephrine) (33). As in some other modem treatments, eg, xanthines and anticholinergics, the roots of P2" go Ast therapy for asthma can be found in historical records which document the use of herbal extracts containing ephedrine [299-42-3] C qH NO, (2) as bronchodilators. Epinephrine and ephedrine are stmcturaHy related to the catecholamine norepinephrine [51-41-2] CgH NO, (1, R = H), a neurotransmitter of the adrenergic nervous system (see Neuroregulators). 

The following documents and records should be reviewed as appropriate, and observations noted. Some of these documents may not be available as they can contain proprietary information for other clients. Place emphasis on determining whether the toller has established procedures and a management system adequate to ensure ongoing compliance. 

Saponara, Anthony, and Randy A. Roig, Ph.D. ISO 14001 Environmental Management Systems A Complete Implementation Guide. Vancouver ERM-West, Inc. and STP Specialty Technical Publishers Inc., 1998. - A very extensive, two-volume ISO 14001 implementation manual containing dozens of checklists, prototype charts, templates, document examples, and other tools. Uses Green Acres Hotel and Resort as a case illustration for presenting implementation principles, techniques, and tools. 

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