Concanavalin

FIGURE 16.3 Glycodendrimer-mediated protein aggregation in solution, (a) Structures of the Man-coated PAMAM dendrimers with G values referring to various dendrimer generations, (b) Transformation of uncomplexed Con A to the cross-linked state in the presence of a glycodendrimer. 

FIGURE 16.4 (a) Glycodendrimer-coated gold nanoparticles used for protein detection 

FIGURE 16.5 A schematic representation of (a) SPR competitive and (b) direct binding assays of Con A-Man recognition, (c) The structure of clicked [G3]-Man glycodendrimer used for studying the glycoside cluster effect. 

FIGURE 16.6 Scanometric strategy for the in situ detection of Man groups on living cells. 

---

Purified by dissolving in Triton X-100 and deoxycholate, and by affinity chromatography on concanavalin A-Sepharose and AMP-Sepharose [Grondal and Zimmerman Biochem J 245 805 1987]. 

Figure 26.6 (a) The /3-pleated sheet secondary structure of proteins is stabilized by hydrogen bonds between parallel or antiparallel chains, (b) The structure of concanavalin A, a protein with extensive regions of antiparallel / sheets, shown as flat ribbons. 

Concanavalin A, secondary structure of. 1038-1039 Concerted reaction, 1178 Condensation reaction, 882 Condensed structure, 22 Cone cells, vision and, 504-505 Configuration. 297... 

CMETS 150 Coatings, fuzzy 151 Complement 171 Concanavalin A 145 Contact area, hydrophobic 159... 

Concanavalin A is a plant lectin from the jack bean (Canavalia ensiformis) which binds with high affinity to mannose residues of glycoproteins. Concanavalin A is known to stimulate the tyrosine kinase activity of the INSR (3-subunit with consecutive activation of kinases downstream the insulin receptor (IRS, PI 3-kinase). It is believed that Concanavalin A stimulates the activation and autophosphorylation of the INSR kinase through aggregation of the receptor, although the precise mechanism of action is unclear. 

Concanavalin, 2, 773 Concanavalin A, 6,572 manganese, 6,587 Concentration mineral processing flotation, 6,780 Concerted electron transfer oxidases, 6,683... 

FIG. 2 (a) Model of two concanavalin A molecules approaching each other in a staggered orienta-... 

Fig. 4. Molecular mass distribution of Fraction A purified on Concanavalin A -cellulose on Superose 12 column. Buffer - 0.05 M phosphate, pH 7.0, 0.15 M NaCl, fraction size 0.5 ml/min. Exopolygalacturonase activity determined with penta(D-galactosiduronic) acid pH 5.0 and pH 3.8 (0—0)-...

Con A Concanavalin A COPD Chronic obstructive pulmonary disease COS Fibroblast-like kidney cell line established from simian cells CoVF Cobra venom CP Creatine phosphate Cp Caeruloplasmin c.p.m. Counts per minute CPJ Cartilage/pannus junction Cr The chemical symbol fir chromium CR Complement receptor CRl, CR2 CR4 Complement receptor types 1, 2 and 4 CR3-a Complement receptor type 3-[Pg.281]

B28. Bladon, P. T., Rowlands, T. E., Whittaker, J. A., and Oakey, R. E., Serum cortisol binding capacity measured with concanavalin A-Sepharose in patients with a recent inflammatory response. Clin. Chim. Acta 253,9-20 (1996). 

Complement (protein in the blood /Lymph from guinea pig)[21] Concanavalin A[22]... 

Silica gel coated with dextran or agarose Protein A, concanavaline A [139]... 

---