Chromatograph-mass spectrometer

Liquid chromatograph/mass spectrometer (LC/MS) interface. An interface between a liquid chromatograph and a mass spectrometer that provides continuous introduction of the effluent from a liquid chromatograph to a mass spectrometer ion source. 

The high temperatures in the MHD combustion system mean that no complex organic compounds should be present in the combustion products. Gas chromatograph/mass spectrometer analysis of radiant furnace slag and ESP/baghouse composite, down to the part per biUion level, confirms this behef (53). With respect to inorganic priority pollutants, except for mercury, concentrations in MHD-derived fly-ash are expected to be lower than from conventional coal-fired plants. More complete discussion of this topic can be found in References 53 and 63. 

Method 1613 of US Environmental Protection Agency (US EPA) was used for the PCDD detection in the objects of environment (water, soil etc.). PCDD detection was done with the help of Polaris Q gas chromatograph/ mass spectrometer on mass-spectrum of electronic impact in the MS-MS mode. Division of isomer PCDD was carried out on a capillary column from the sintered quartz DB-5 MS (60 m x 0,25 mm, thickness of tape 0,25 p.m). The same device was used for detection of fungicides formulations active ingredients in soil. 

Some detectors can give additional information about the elutes (the eluted solutes). One example is the gas chromatograph—mass spectrometer (GC-MS), which produces a mass spectrum of each compound as well as its mass and location in the chromatogram. This powerful means of detection can be used when standard samples are not available to help determine the identities of the solutes. A beam of ions bombards each compound as it emerges from the chromatograph. The compound breaks up into ions of different masses, providing a spread of narrow peaks instead of one peak for each compound. The relative amount of each fragment is determined and used to help identify the compound. 

A chemist treats toluene (methylbenzene) with chlorine in the presence of a metal catalyst. A sample of the reaction mixture is injected into a GC-MS unit (gas chromatograph-mass spectrometer). One of the compounds that is separated... 

Glass screw-cap autosampler vial, 2-mL, with Teflon-lined septum Fisons MD-800 gas chromatograph/mass spectrometer or equivalent MassLynx Software, Version 2... 

Detector wavelength Injection volume Retention time for fenoxycarb Gas chromatograph/ mass spectrometer Column... 

Greaves et al. [74] used a selected ion-monitoring assay method for the determination of primaquine in plasma and urine using gas chromatography-mass spectrometric method and a deuterated internal standard. After freeze-drying and extraction with trichloroethylene, the sample plus internal standard was reacted with Tri Sil TBT (a 3 3 2 by volume mixture of trimethylsilylimidazole, A/O-bis-(trimethylsilylacetamide and trimethylchlorosilane) and an aliquot injected to the gas chromatograph-mass spectrometer. The gas chromatographic effluent was monitored at m/z 403, and m/z 406, the molecular ions of the bis-tetramethylsilane ethers of primaquine and 6-trideuteromethoxy primaquine. 

D. I. Carroll, I. Dzidic, R. N. Stillwell, K. D. Haegele and E. C. Homing, Atmospheric pressure ionization mass spectrometry. Corona discharge ion source for use in a liquid chromatograph mass spectrometer computer analytical system, Anal. Chem., 47, 2369 2373 (1975). 

Chian et al. [69] point out that the Bellar and Iichtenberg [65] procedure of gas stripping followed by adsorption onto a suitable medium and subsequent thermal desorption onto a gas chromatograph-mass spectrometer is not very successful for trace determinations of volatile polar organic compounds such as the low molecular weight alcohols, ketones, and aldehydes. To achieve their required sensitivity of parts per billion, Chian et al. [69] carried out a simple distillation of several hundred ml of sample to produce a few ml of distillate. This achieved a concentration factor of between 10 and 100. The headspace gas injection-gas chromatographic method was then applied to the concentrate obtained by distillation. 

The GAGI samplers, installed along traverses at both Honerat and Unknown, were left in place for 5 months before being retrieved. Retrieved samplers from both locations were sent to Gore Laboratories where they were heated, and compounds were thermally desorbed and analyzed with a gas chromatograph/mass spectrometer (GC/MS). 

Fig. 16.1 Gas-chromatograph mass spectrometer profile of scent from the anal scent gland of three adult female spotted hyenas from the same social group...

C.R. Blakley, J.C. Carmody and M.L. Vestal, Liquid chromatograph-mass spectrometer for analysis of nonvolatile samples, Anal. Chem., 52 (1980) 1636-1641. 

GCMS-QP 2000 gas chromatograph mass spectrometer, GCMS-Q 1000 and GC-QP 1000A gas chromatograph mass spectrometer Mispack 200 GCMS QP series MS data system... 

Mass-spectral (MS) Analysis. Mass spectral analyses were obtained using a computerized Finnigan Model 1015 gas chromatograph-mass spectrometer (GC-MS) operated at 70 eV. Samples were introduced via direct insertion probe or by utilizing the GC-MS combination, both operated over a programmed temperature range. 

CarroU, D.I. Dzidic, 1. StUlweU, R.N. Haegele, K.D. Homing, E.C. Atmospheric Pressure lonization-MS. Corona Discharge Ion Source for Use in a Liquid Chromatograph-Mass Spectrometer-Computer Analytical System. Anal. Chem. 1975,47, 2369-2373. 

Lao, R. C., R. S. Thomas, H. Oja, and L. Dubois. Application of a gas chromatograph-mass spectrometer-data processor combination to the analysis of the polycyclic aromatic hydrocarbon content of urbome pollutants. Anal. Chem. 45 908-915, 1973. 

Pereira, W.E., Short, D.E., Manigold, D.B., and Roscio, P.K. Isolation and characterization of TNT and its metabolites in groundwater by gas chromatograph-mass spectrometer-computer techniques, Bull. Environ. Contam. Toxicol., 21 (4/5) 554 -562, 1979. 

Subsequently, modified thermal decomposition systems were developed by the University of Dayton to investigate the destruction of complex hazardous waste mixtures ]). These systems utilized various combinations of gas chromatographs/mass spectrometers/computers which were incorporated into the vaporization and decomposition process. 

Analysis of the Mixture of Organic Compounds from the Soil. The crude fractions were analyzed using a LKB-2091 capillary gas chromatograph/mass spectrometer/data analysis system (CGC/MS/DA). The capillary column used was a J W DB-1, 60 m x 0.32 mm, connected directly to Ae ion source of the mass spectrometer. Up to 1.0 tfL of a solution of the sample in an appropriate solvent was injected directly onto the column at 40 °C, whereupon the column temperature was immediately raised to 100 for 4 min, and programmed to 310 °C at a rate of 10°/min. and held there for 30 min. 

Gas-chromatograph mass spectrometer operating in the negative chemical ionization mode. 

Gardner AM, Warren VL, Chen JT, et al. 1979. A metabolite of polybrominated biphenyls Its identification and decomposition to a brominated dibenzofiiran in the gas chromatograph-mass spectrometer. J Agric Food Chem 27(1) 116-119. 

Ryhage, R. 1967. Identification of fatty acids from butter fat using a combined gas chromatograph mass spectrometer. J. Dairy Res. 34, 115-121. 

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